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Circulating miR-126-3p and miR-423-5p Expression in de novo Adult Acute Myeloid Leukemia: Correlations with Response to Induction Therapy and the 2-Year Overall Survival

The study aimed to compare the expression of miR-126-3p and miR-423-5p in patients and normal subjects, and correlate their expression with response to induction therapy. Circulating miR-126-3p and miR-423-5p were measured in the plasma of 43 adult AML patients and 35 age- and sex-matched controls by real time PCR. The foldchange in differential expression for each gene was calculated using the comparative cycle threshold (CT) method (also known as the 2−CT method). For statistical purposes, the fold change was calculated using DDCT (or 2–∆∆Ct) method to find the relative expression of miRNAs. The expression fold change of miR-126-3p was 1.73-fold increase in patients than controls (p= 0.010). The expression fold change of miR-423-5p was a 2.13-fold increase in patients than controls (p=0.003). No significant correlation was found between the expression of miR-126-3p and miR-423-5p in the studied AML patients, (r=0.094, p=0.22). Furthermore, no relationship was found between the expression of the studied miRNAs and response to induction therapy. Conclusions Although a significant increase in the levels of circulating miR126-3p and miR-423-5p expressions was found in AML patients but this was not correlated with induction remission status.

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Publication Date
Fri Sep 15 2023
Journal Name
Al-academy
Drawing inspiration from organic natural forms in stereoscopic sculptures (A survey according to Evo-devo science)

By reading the book (Endless Forms Most Beautiful: The New Science of Evo Devo) by Sean B. Carroll, new horizons opened up about the nature of the formation of the living organism. Although he presented the idea that the artist was influenced by the material assets of nature in his holographic art formations, the new science of Evo-Devo (Evolutionary Developmental Science) provided models worth standing on when comparing the similarity of the formation of living organisms on the one hand, and the formation of works of art with holographic organic bodies on the other. But the excitement lies in the fact that the formation of living natural organisms is often driven by subtle intelligent mechanisms that are different from the mechanisms us

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Publication Date
Wed May 25 2022
Journal Name
Iraqi Journal Of Science
Developing a Heuristic Algorithm to Solve Uncertainty Problem of Resource Allocation in a Software Project Scheduling

     In project management process, the objective is to define and develop a model for planning, scheduling, controlling, and monitoring different activities of a particular project. Time scheduling plays an important role in successful implementation of various activities and general outcome of project. In practice, various factors cause projects to suffer from time delay in accomplishing the activities. One important reason is imprecise knowledge about time duration of activities. This study addresses the problem of project scheduling in uncertain resource environments, which are defined by uncertain activity durations.  The study presents a solution of the levelling and allocation problems for projects that have some uncertain ac

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Publication Date
Fri Jun 24 2022
Journal Name
Iraqi Journal Of Science
Using Computer Processing Interpretation (CPI) Technique to Evaluate Mishrif Formation in Garraf Oil Field, Southern Iraq

The aim of this study is to determine and evaluate the units and subunits of Mishrif Formation in Garraf oil field 85 km north of Nasiriyah city depending mainly on the geophysical well logging data and other amiable geological information. The sets of the geophysical well logs data acquired from GA-4, GA- AIP, GA- B8P, GA-3 and GA-5 wells of Garraf oil field are used to determine the petrophysical and lithological properties for each zone in Mishrif Formation to locate, define and evaluate hydrocarbon production from each zone in the reservoir which is also known as formation evaluation. The digitization was done by using Didger software and the interpretations were made using Interactive Petrophysics Program v 3.5 and Petrel software.

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Publication Date
Thu Aug 31 2023
Journal Name
Journal Of Legal Sciences
Rules for Sustainable Development to Protect Working Women in Iraqi Labor Law No. 37 of 2015

Our research dealt with the issue of sustainable development related to the legal rules of the labor law in force to achieve the necessary protection for the rights of working women. The Iraqi labor law in force set several rules inspired by the texts of international conventions to protect working women at work. These rules were summarized in our research to the rules of protection from sexual harassment. At work, and the basis for obtaining decent work for women at work, Iraq was one of the countries organizing the Convention (CEDAW) that combats sexual harassment and gender discrimination, and which called for the importance of the presence of women in developing society and achieving the global goals of sustainable development. Devel

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Publication Date
Tue Nov 26 2024
Journal Name
Journal Of Baghdad College Of Dentistry
Oral health status in relation to selected salivary elements among a group of gasoline stations workers

Background: Gasoline constituents and its derivatives had many hazardous effects on the general health of humans. Thus, gasoline stations workers may be affected by different types of related diseases.This study was conducted to assess selected salivary elements and their relation with dental caries, oral hygiene status and periodontal diseases among gasoline stations workers in comparison with individuals have no regular exposure to gasoline. Materials and methods: The study group consists of thirty male subjects with an age range (33-39) years who worked in different gasoline stations in different areas of Baghdad city and thirty persons that matching in age and gender and not exposed to gasoline were selected as a control group. Dental c

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Publication Date
Tue Nov 26 2024
Journal Name
Journal Of Baghdad College Of Dentistry
Salivary antioxidants in relation to dental caries among a group of lead-acid batteries factory workers

Background: Lead-acid battery workers are at higher risk for systemic diseases as well as oral diseases like dental caries. The aim of this study was to assess selected salivary antioxidants and their relation with dental caries among lead acid battery factory workers in comparison with non-exposed group. Materials and methods: The sample consisted of 35 subjects aged 35-45 year-old who worked in Babylon lead acid battery factory in Baghdad city and matching group that not exposed to lead were selected as a control. Dental caries severity was recorded by using DMFS index, stimulated salivary samples were collected and analyzed for the measurement of salivary antioxidants (uric acid, total protein, catalase and glutathione peroxidase enzymes

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Publication Date
Sun Jul 31 2022
Journal Name
Iraqi Journal Of Science
Implementation of Seismic Inversion to Determine Porosity Distribution of Maysan in Amara Oil Field, Southern Iraq

The current research deals with studying the petrophysical properties represented by the porosity and its distribution on the level of all units of the top and bottom of the Kirkuk Formation Group. The study area is located in Maysan province in the south-eastern part of Iraq in the Amara field. The Kirkuk Group was deposited in the Tertiary Age. The post-stack method using seismic inversion and creating a relationship between seismic data was accomplished using Hampson-Russel software at well Am-1 and Seismic lines Ama 20 and 30. The research results indicate high porosity values on top of the formation with a decrease in acoustic impedance (Z) and, therefore, a reduction in the density. At the same time, low porosity values were indica

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Publication Date
Thu Feb 01 2018
Journal Name
Journal Of Engineering
Aspects of General & Secondary Indicators that form a Local System to assist Sustainability Verification in Buildings

The research focuses on how to reach a mechanism that assists experts, engineers, and others in the architectural & engineering project to verify the co-existence of values and sustainability constituents in it. Research problem shows a clear lack, locally, in the interest to establish a value system and a list that cares about comprehending building components whether considering sustainable building criteria. Hypothesis shows that in order to head towards the applicable sustainable approach of buildings, then a local assessment system should be established to evaluate buildings during its life cycle, and from which buildings would be categorized as sustainable or not. Research aims at establishing main and general

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Publication Date
Tue Dec 01 2020
Journal Name
Journal Of Economics And Administrative Sciences
Assessing liquidity to improve bank’s profitability : An applied research - in a number of – Iraqi private banks

The current research aims to evaluate liquidity (as an independent variable) to improve the bank’s profitability (as a dependent variable ), by the bank’s ability to maximize its profits from its business results without excessive bank’s  liquidity, so that may affect negatively affects the bank’s reputation and it’s dealers confidence in facing their financial obligations. and this may lead trying to come out among other recommendations including contributing to obtain, the bank’s ability to achieve liquidity balance to maximize its profits. This research has been applied to the sample induced intentionally by choosing three Iraqi private banks. The researcher used financial indicators to assess the bank’s liq

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Publication Date
Tue Nov 26 2024
Journal Name
Journal Of Physical Education
The Effect of Special Exercises Using Rubber Ropes on The Development of Some Physical Abilities and Achievement in F56 Female Discuses Thrower Class

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