Background: Hepatic ischemia-reperfusion (I/R) injury may occur in a variety of clinical set­tings and this remains a significant problem. Oxygen free radi­cals, produced on reperfusion have been shown to play a major role in hepatic I/R injury. Various therapeutic effects have been described for Zingiber officinale. Additionally, it has been presented that Zingiber officinale has protective effect against ischemia reperfusion injury to various organs. Therefore, it seems possible that the administration of Zingiber officinale might protect the liver against the ischemia reperfusion  injury.

Objectives : To determine whether Zingiber officinale prevents hepatic ischemia-reperfusion injury to the liver.

This study sheds light on various drugs of plant origin which have shown action on thyroid and its functioning as well as on the various factors associated with thyroid dysfunction. Therefore, the aim of this study is to determine the activity of the aqueous extracts of Fucus vesiculosus, Coleus forskohlii, Curcuma longa L., Rosmarinus officinalis L., Camellia sinensis L. and Melissa officinalis L. in regulation of thyroid hormones in serum taken from rats. Fifty-seven female albino rats were divided into 19 groups, each group with 3 rats, and treated orally with an aqueous plant extract in three different doses, except the control group which was treated with normal saline only. Also, a histological s

Many researches focused on laser therapy of wound healing in different animal models due to the lack of a standard protocol in the application of such phototherapy. Objective:  To study the effects of 810nm laser at a constant irradiance of 41.63 mw/cm² and exposure (illumination) time of 5,15  minutes on wounds created on Albino mice (BALB/c).

     Skin wound with elliptic shape and full thickness was created on the dorsal side of  â€˜45 mature male albino mice. Irradiated animals were divided into two main groups based on irradiation time, the first was irradiated for 5 min and the second for 15 min, each was subdivided into three subgroups (n=5) according to number of treatment

Background: As acetaminophen (APAP) toxicity has become more common in many countries, related cases of poisoning, whether deliberate or unintentional, have been identified as a key contributor to acute liver failure. Aime: To discover if omega-369 fatty acids could protect the liver of male mice from the effects of acetamiophen. Methods: Thirty-five albino male mice were allocated to one of five groups at random. Group 1 served as the "negative control" and received a single intraperitoneal injection (10 ml/kg) of normal saline on the eleventh day of the test following ten days of receiving liquid paraffin orally at a dose of 10 ml/kg. The liquid paraffin was given to group 2 "positive control". Group 3 received Omega 369 (50 mg/kg

5-fluorouracil (5-FU) is a is Pyrimidine analogue widely used in the treatment of various malignancies It belongs to  the antimetabolites family that acts during the S-phase of the cell cycle thus it prevents DNA synthesis.N-acetylcysteine is nutritional complement acts as antioxidant.The purpose  of the current study is to investigate whether there is a protective  role  of N-acetylcystein against intestinal toxicity induced by 5-fluorouracil in albino rats.18 healthy adult rats were distributed into 3 groups of 6 rats for each. Group A as a control group.Group B injected with 5-FU (20 mgs dissolved in 2ml normal saline per kilogram body weight intraperitoneally for 7 successive days while Group C received N-acetylcy

     In this study, the potential combined effects of silver (AgNPs) and silicon dioxide nanoparticles (SiO₂NPs) on male albino mice which were exposed intraperitoneally to the 50 mg/kg and 100 mg/kg and mixed concentrations of nanoparticles (NPs) for periods of 2 and 4 weeks, were evaluated. The evaluation was performed by examining the haematological and biochemical parameters, in addition to the bioaccumulation of NPs in the liver and kidney. The results showed that the platelets count significantly increased in all exposed groups, while red blood cell count (RBCs) decreased in most exposed groups. White blood cells (WBCs) and haemoglobin (Hb) showed different levels in the exposed groups. Serum aspartate aminotransfera

Asthma is a chronic respiratory disorder in which immunological and structural cells play a role. The limits of conventional medicines necessitate the development of innovative therapeutic techniques for asthma. In the present study, we investigated the possible protective effect of cinnamic acid (CA) on ovalbumin-induced asthma in a mouse model. Sixty albino male mice BALB/c type weighing (20-30) grams were chosen at random and divided into five groups each one contains 12 animal: Group I: PBS/liquid paraffin control. Group II: asthma model group. Group III: cinnamic acid control group; mice received cinnamic acid (50 mg/kg) in liquid paraffin orally by gavage. Group IV: asthma model / group of (25 mg / kg) cinnamic acid; mice received

Strong evidence showed that many medicinal plants have the potential to reduce hyperlipidemia disease. The aim of this study was to determine the hypolipidemic activity of aqueous extracts of Fucus vesiculosus, Coleus forskohlii, Curcuma longa L., Rosmarinus officinalis L., Camellia sinensis L. and Melissa officinalis L. on lipid profile in serum taken from the blood of rats. Fifty-seven female albino rats were divided into 19 groups, each with three rats, that were treated orally with an aqueous plant extract in three different doses, except the control group which was treated with normal saline only. The chemical compositions of these extracts were analyzed using High Performance Liquid Chromatograph