BSTRACT: BACKGROUND: Acne vulgaris(AV)is chronic inflammatory disease of pilosebaceous unit of young people. Patients with acne with or with out scarring might differ in regard to their immunological background from those free from acne. OBJECTIVES: To evaluate the problem of facial AV especially patients with scarring and to determine the frequency of associated skin diseases and to be compared with acne free control. METHODS: A cross sectional randomized controlled epidemiological study was conducted from Oct.2005-Oct. 2006.Three hundred students from Basra University; 132 (44%) males and 168 (56%) females were enrolled, their ages ranged from 18-25 (20.9±1.8) years. They were divided into: Group A those free from acne (98 individuals),Group B with non scarring facial AV (96 patients), and Group C with scarring facial AV (106 patients). History and examination were done for their acne, scarring acne and associated skin diseases. Allen and Smith grading system for AV were used, and a new invented multiparametric scoring system for scarring acne was applied. RESULTS: AV was in 98(73.24%) males and 104 (61.9%) females. Scarring was 54 (50.95%) males and 52 (49.05%) females. Greasy skin was the most common type among Group B 67 (69.8%) versus 39 (39.8%) among Group A(P=0.000029) and was more common among Group C 84(79.2%) (P=0.00000001).Family history of AV was nearly similar in A and B Groups 55(57.29%) and 56 (52.83%) respectively, while in Group A was 39 (39.79%). Family history of scarring acne was in 35(33.02 %) of Group C, 16 (16.66 %) of Group B, and 3 (3.1%) in Group A; (P=0.00000017). The age of onset was similar in A and B Groups between 15-16 years. Majority of patients in Group B had non inflammatory type or mild inflammatory (papular) 65 (67.8%) patients, most of case were mild and moderate 86 (89.58%) patients, while high percent in Group C had inflammatory type 95 (89.62%), and more than half of them had severe and very severe types upon grading 56 (52.8%). The aggravating factors were similar in A and B Groups with stress and hot weather being the leading aggravating factors. Squeezing and digging habit was in 53 (50%) in Group C versus 23 (23.95%) in Group B (P=0.00024). In most cases of scarring acne, scarring was mild and moderate 85 (80.19%), and the most common type scars was the flat hyperpigmented [50 (47.17%) and 66 (62.26%) respectively].The most common effect of scarring acne on psyche was mild discomfort and mild dysmorphophobia 75 (70.75%).Associated skin diseases were more common among Group A 31 (31. 63%) than among Group B 22 (22.91%) and least common among Group C 14 (13.20%) (P=0.0067) and they were mainly dermatitis and skin infections. CONCLUSION: AV might reflect the immunological status especially among patients with scarring. The frequency of skin diseases was much less among patients with scarring acne
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This comprehensive review examines the efficacy and safety of tumor necrosis factor-alpha (TNF-α) inhibitors in treating various autoimmune diseases, and focuses on their application in Iraqi patients. Elevated TNF-α levels are linked to autoimmune disorders, leading to the development of anti-TNF-α therapies such as infliximab, etanercept, adalimumab, certolizumab pegol, and golimumab, which have gained FDA approval for conditions like psoriasis, in¬flammatory bowel disease, ankylosing spondylitis, and rheumatoid arthritis. While these therapies demonstrate sig¬nificant therapeutic benefits, including improved quality of life and disease management, they also carry risks, such as increased susceptibility to infections and pote
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This study was conducted with the aim to extract and purify a polyphenolic compound “ Resveratrol†from the skin of black grapes Vitis vinifera cultivated in Iraq. The purified resveratrol is obtained after ethanolic extraction with 80% v/v solution for fresh grape skin, followed by acid hydrolysis with 10% HCl solution then the aglycon moiety was taken with organic solvent
( chloroform). Using silica gel G60 packed glass column chromatography with mobile phase benzene: methanol: acetic acid 20:4:1 a
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Airlift reactors are widely used in the chemical and biochemical applications as effective contactors for mass and heat transfer. The main advantages of airlift contactor compared with simple bubble column are ease of construction, low shear rate, high capacity, good mixing and liquid circulation without mechanical agitators and circulating pumps.
In this work, growth characteristics of Chlorella vulgaris microalgae were studied in an internal loop airlift photobioreactor for biomass production. The bioreactor operated under batch and semi-continuous culture mode using commercially available 20:20:20+TE NPK fertilizer as nutrients. The experiments were conducted to evaluate the growth rate and biomass productivity of
... Show MoreIn this review of literature, the light will be concentrated on the local drugs delivery systems for treating the periodontal diseases. Principles, types, advantages and indications of each type will be discussed in this paper.
The relationship between the clinical singes and some of the hematological and biochemical values in 126 cases of local breed and Shammi breed goats (from both sexes) diagnosed as cases of malnutrition from 230 goats examined .The clinical examination include (beside the general inspection and case history) body temperature, respiratory and pulse rates, mucus membranes skin and coat. Examination of the blood samples included RBCs count, Hb concentration, PCV % and values of cupper, magnesium, phosphorus, and potassium. The results showed that the mean body temperature of these goats was lower than in normal goats, while the respiratory and pulse rates were higher .Examination of blood revealed decrease in the means of RBCs counts ,Hb con
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