يعد تحليل العلاقات الكمية بين البنية والممتلكات/النشاط (QSPR/QSAR) أمرًا بالغ الأهمية لفهم خصائص المركبات المرتبطة بالمخدرات، خاصة في علاج مرض الزهايمر. في هذه الدراسة، هدفنا هو استخدام أساليب مبتكرة بما في ذلك استخدام المؤشرات الطوبولوجية -درجة و- درجة ، المستمدة من نظرية الرسم البياني، لتقييم الخصائص والخصائص الفيزيائية والكيميائية لخمسة أدوية لمرض الزهايمر: تاكرين، دونيبيزيل، ريفيستيجمين، جالانتامين و والهوبرزين أ . تقدم هذه المؤشرات الطوبولوجية طريقة جديدة لالتقاط المعلومات الهيكلية الجزيئية الأساسية، مما يقلل من عدد الواصفات مع تعزيز ارتباطها بالخصائص الجزيئية المتنوعة. ومن خلال الحسابات الشاملة لهذه المؤشرات، هدفنا هو توضيح الخصائص الجزيئية المعقدة لأدوية مرض الزهايمر. علاوة على ذلك، أجرينا تحليلات QSPR وQSAR لربط المؤشرات الطوبولوجية المحسوبة بالخصائص الفيزيائية والكيميائية المختلفة للأدوية. في حين أن الأساليب المبتكرة المستخدمة في دراستنا توفر رؤى قيمة. لا تساهم النتائج التي توصلنا إليها في تعزيز فهمنا لخصائص أدوية مرض الزهايمر فحسب، بل تحمل أيضًا آثارًا على تطوير الأدوية وتحسينها في إدارة مرض الزهايمر. ومن خلال تعزيز معرفتنا بخصائص هذه المركبات، فإن هدفنا هو معالجة الطبيعة المتعددة العوامل لمرض الزهايمر وتحسين التدخلات العلاجية.
Objectives: To assess nurses-midwives' knowledge about pain management during labor before and after implementation of educational program and to determine the effectiveness of educational program on nurses-midwives' knowledge about pain management during labor in Baghdad Maternity Hospitals.
Methodology: A quasi-experimental design has been conducted during the period of (February 27th 2019 through 2nd June 2019) on non-probability sample (purposive) consists of (44 Nurses/midwives') who are work in delivery room, the sample was exposed to pretest, educational program, posttest. The study was conducted in three Directories, (Baghdad Teaching Hospital) at medical city health
... Show Moreنحو تعزيز المشاركة السياسية للطالبات الجامعيات الفلسطينيات
In this work pyrazolin derivatives were prepared from the diazonium chloride salt of 4-aminobenzoic acid. Azo compounds were prepared from the reaction of an ethanolic solution of sodium acetate and calculated amount of active methylene compound namely, acetyl acetone to obtain the corresponding hydrazono derivative (1). Cyclocondensation reaction of compounds (1) with hydrazine hydrate and phenyl hydrazine in boiling ethanol affording the corresponding pyrazoline-5-one derivatives of 4-aminobenzoic acid (2,3). Then compound (3) was reacted with thionyl chloride to give the corresponding acid chloride derivative(4), followed by conversion into the corresponding acid hydrazide derivative (5) carboxylic acid thiosemicarbazide (11), esters
... Show MoreThe paper presents the design of a system consisting of a solar panel with Single Input/Multiple Outputs (DC-DC) Buck Converter by using Simulink dialogue box tools in MATLAB software package for simulation the system. Maximum Power Point Tracking (MPPT) technique depending on Perturb and Observe (P&O) algorithm is used to control the output power of the converter and increase the efficiency of the system. The characteristics of the MSX-60 PV module is chosen in design of the system, whereas the electrical characteristics (P-V, I-V and P-I curves) for the module are achieved, that is affected by the solar radiation and temperature variations. The proposed design module has been found to be stable for any change in atmospheric tempera
... Show MoreThis research is carried out to investigate the behavior of self-compacting concrete (SCC) two-way slabs with central square opening under uniformly distributed loads. The experimental part of this research is based on casting and testing six SCC simply supported square slabs having the same dimentions and reinforcement. One of these slabs was cast without opening as a control slab. While, the other five slabs having opening ratios (OR) of 2.78%, 6.25%, 11.11%, 17.36% and 25.00%. From the experimental results it is found that the maximum percentage decrease in cracking and ultimate uniform loads were 31.82% and 12.17% compared to control slab for opening ratios (OR
... Show MoreHeart failure (HF) is characterized by family history and clinical examination combined with diagnostic tools such as electrocardiogram, chest x-ray and an assessment of left ventricular function by echocardiography. An early diagnosis of heart failure is still based on symptoms of dyspnea, fatigue and signs of fluid overload. Serum N-terminal pro-B-type natriuretic peptide (NT-pro BNP) is cardiac biomarker has emerged as potential predictor of heart failure. It is used as a sensitive biomarker in diagnosis and assessment severity of heart failure. This study assed the diagnostic value of (NT-pro BNP), in Iraqi children patients with heart failure and its correlation with LVEF% especially in emergency rooms of hospitals.Ninety (90) consecut
... Show MoreBackground: Tooth wear is one of the most common problems in the older dentate population which results from the interaction of three processes (attrition, abrasion and erosion) and it affects all societies, different age groups, and all cultures. This study was achieved to evaluate the prevalence and distribution of tooth wear among institutionalized residents in Baghdad city\ Iraq. Subjects and Methods: This survey was accomplished on four private and one governmental institution in Baghdad city. One-hundred twenty three (61 males, 62 females) aged 50-89 years were participated in this study. The diagnosis and recording of tooth wear were according to criteria of Smith and Knight. Results: The prevalence of tooth wear was 100% with a mean
... Show MoreObjective: The study aimed to identify the adolescents' family meal eating patterns, and find out the relationship between adolescents' family meal eating patterns and their weight control behaviors. Methodology: A descriptive study was conducted on impact of adolescents' family meal eating patterns upon their weight control behaviors in secondary schools at Baghdad city, starting from 20th of April 2013 to the end of October 2014. Non- probability (purposive) sample of 1254 adolescents were chosen from secondary schools of both sides of Al-Karkh and Al-Russafa sectors. Data was collected through a specially