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The Correlation of P53 and MSI Immune Markers in Gastric Adenocarcinoma
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العلاقة بين تعبير المعلمات المناعية ل (P53) وعدم استقرار الساتل الميكروي  (MSI) مع العوامل السريرية المرضية لسرطان المعدة الغدي باستخدام الكيمياء النسيجية المناعية. الخلاصة الخلفية: يحدث سرطان المعدة الغدي بسبب عدم استقرار الكروموسومات، وطفرات TP53، واختلال الصيغة الصبغية، والانتقالات، والجينات الورمية الأولية، والتغيرات الجينية المثبطة للورم.عدم استقرار الساتل الميكروي(MSI)  يسبب فشل إصلاح عدم تطابق الحمض النووي، مما يؤثر على دقة تكرار الحمض النووي. يم الكشف عن أخطاء النسخ المتماثل المبكرة بواسطة مجمع البروتين المتغاير  (hMSH2/hMSH6) ، الذي يقوم بتفعيل hMLH1) و(hPMS2  لإعادة تكوين الحمض النووي. يحدث عدم استقرار الساتل الميكروي في حالات سرطان المعدة المتفرق ومتلازمة لينش. الهدف من الدراسة: دراسة العلاقة بين تعبيرالمعلم P53 وتعبير المعلمات المناعية لـعدم استقرار الساتل الميكروي (MSI) مع العوامل السريرية المرضية لسرطان المعدة الغدي باستخدام الكيمياء النسيجية المناعية. المواد والطرق: تم فحص 40 كتلة من نسيج سرطان المعدة الغدي المثبت بالفورمالين والمطمور بالشمع في بغداد، العراق. تناولت الدراسة حالات سرطان المعدة الأولية، مع البيانات السريرية المرضية المتاحة، والأنسجة الجراحية. التعبير المناعي الكيميائي الذي تم تقييمه بواسطة نظام تسجيل النقاط. تم استخدام برنامج SPSS لتحليل البيانات، كما تم استخدام اختبارات Chi-square واختبارات Fisher الدقيقة لتقييم الارتباطات. تم اعتبار مستوى الثقة 95٪ والقيمة الاحتمالية P 0.05 أو أقل مهمًا. النتائج : كان التصبيغ المناعي النسيجي الكيميائي لـ P53 إيجابيًا في 65٪ من الحالات، بينما كانت نتائج MSI إيجابية في 97.5٪ من الحالات. حصل الزوجان المتغايران MLH1/PMS2 على نتائج إيجابية بنسبة 32.5% ونتائج سلبية 67.5%، في حين حصل الزوجان المتغايران MSH2/MSH6 على نتائج إيجابية بنسبة 87.5% ونتائج سلبية 12.5%. ارتبطت صبغة P53 بشكل كبير بانتشار العقدة الليمفاوية  ودرجة الورم ، ولكن لم يكن هنالك ارتباط مع العوامل الأخرى. لم يتم العثور على ارتباط كبير بين معلمات MSI والعوامل المدروسة,لم يكن هناك ارتباط كبير بين معلمات MSI غير المتجانسة (MLH1 / PMS2) والمعلمات المرضية السريرية، ولكن كان هناك ارتباط كبير بين علامات MSI الزوجين غير المتجانسة (MSH2 / MSH6) والنقائل فقط . الاستنتاج: : يعد P53 معلما حيويا مهما لتقييم انتشار العقدة الليمفاوية  وعدوانيتها في التصنيف النسيجي، مما يشير إلى التشخيص، وتحديد مرضى السرطان الأكثر عرضة لخطر الإصابة بالورم النقيلي. على الرغم من أن MSH2/MSH6  اظهر ارتباطا مهمًا مع النقائل الورمية ، إلا أن معلمات MSI كان لها أقل قيمة إنذارية في دراستنا. هناك حاجة إلى مزيد من البحث لإثبات فعاليتها في علاج سرطان المعدة.

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Publication Date
Sat Sep 30 2023
Journal Name
Lark
ADJECTIVES WITH THE SUFFIX -OVATE - / - EVAT IN MODREN RUSSIAN LANGUAGE
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يكشف هذا المقال عن مشكلة الصفات ذات المكون الكمي والتي تعتبر واحدة من اقوى الموارد المكونة للكلمات التعبيرية والتقويمية و يتم تحليل التركيبات الدلالية ذات الاوجه المتعددة التي تنشا من عملية توظيف الصفات المشتقة بمساعدة اللواحق والتي تدل على الاتجاه العام للغات السلافية وذلك لتطوير الدلالات العاطفية والتقييمية في الكلمات ذات معنى الميزة او الخاصية يتم تقديم تعريف انماط تكوين المعاني الضمنية في دلالات

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Publication Date
Tue Mar 15 2022
Journal Name
Al-academy
The Graphic privacy in vector graphics design for children's publications
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         The graphic privacy feature is one of the most important specifications for the existence of any type of design achievements alike, which is one of the graphic products with its multiple data, and from here the current research investigates the graphic privacy of vector graphics design with all its technical descriptions and concepts associated with it and the possibility of achieving it to the best that it should be from Where its formal structure in children's publications, where the structural structure of the current research came from the first chapter, which contained the research problem, which came according to the following question: What is the graphic privacy in the design of vector graphics in children's publ

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Publication Date
Sat Sep 01 2018
Journal Name
Indonesian Journal Of Electrical Engineering And Computer Science
The Factors Affecting on Managing Sensitive Data in Cloud Computing
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Cloud computing represents the most important shift in computing and information technology (IT). However, security and privacy remain the main obstacles to its widespread adoption. In this research we will review the security and privacy challenges that affect critical data in cloud computing and identify solutions that are used to address these challenges. Some questions that need answers are: (a) User access management, (b) Protect privacy of sensitive data, (c) Identity anonymity to protect the Identity of user and data file. To answer these questions, a systematic literature review was conducted and structured interview with several security experts working on cloud computing security to investigate the main objectives of propo

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Publication Date
Wed Jan 01 2020
Journal Name
Akkadica
Some Ur III Texts from Irisagrig in the Iraq Museum
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This article publishes seven cuneiform tablets in the collection of the Iraq Museum Baghdad. Six of the tablets have an Irisagrig/Al Sarraki provenance, the seventh is of uncertain origin. They are dated to the reigns of Amar-Suen (AS) and Ibbi-Suen (IS) of the Ur III Dynasty. The texts represent administrative texts of the governing institutions and account for economic activities including the assignment of female workers for wool plucking, the remuneration of canal work with barley and the selection of wool for textiles. Three tablets record offerings in respect of cultic observances, two of which describe the disbursement of foodstuffs for the king's monthly 83-63 offerings to the new moon.

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Publication Date
Tue Sep 19 2017
Journal Name
Al-academy
Aesthetics configuration in the Assyrian winged bull )An analytical study(
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Subjected Find winged bull Assyrian monetary analysis in order to identify the formative relations in terms of percentages, movement and public swab for being aesthetic values ​​upon which the mechanisms of artistic composition, which did not give researchers artistic interest that affects the status of these sculptures and the like of the achievements of the Iraqi civilization in Assyria.

Resulting analysis to a number of the most important results, the percentages approved in the calculation of the parts to do with all when viewed status horizontal with a realistic formulas while in the case of considering frontally clear for Ras stylized proportions and head size larger in length, a ratio confirmed by previous studies, and

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Publication Date
Wed Aug 01 2018
Journal Name
Journal Of Economics And Administrative Sciences
The Economic Analysis for Construction in Ibn Khalduon s’ Muqaddimah
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The specialist researcher  fined the relations between economic ideas with economic facts in his theory which called humanity building it is appeared clearly ( in Ibn Khalduons’ Muqaddimah) in a clothe of economic  social  phenomenon's as a systematical analysis in all fifty chapters of al Muqaddimah ,therefore this paper deal with  Ibn Khalduon economic thoughts as important says which describe the society building in its economic subjective  and  examine the relationship between The dissert and the city within economic says which are cover  the social analysis ,and determinate   the analysis objects  which clearly in this dualism  model ,between the state and economic bas

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Publication Date
Fri Dec 01 2023
Journal Name
Political Sciences Journal
Class consciousness in the contemporary Marxist political thought (selected models)
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Class consciousness represents its highest stage in the contemporary Marxist thought of Rosa Luxemburg and Antonio Gramsci, not just a reflection of reality, but rather a dialectical form through the reflection of consciousness on reality and its reproduction. The superiority over the infrastructure (historical materialism) promised the revolutionary class consciousness to be achieved spontaneously, and the seeds of a breakthrough are mass strikes, denying the role of the party to organize this awareness, limiting its role to the interconnection between classes, emphasizing the role of socialist democracy as a conscious vanguard for organizing spontaneity, struggle, and developing awareness during the revolutionary process and the leader

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Publication Date
Mon Jan 01 2018
Journal Name
Al–bahith Al–a'alami
The Communicative Integration in New Media: Building a Communicative Model
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The internet, unlike other traditional means of communication, has a flexibility to stimulate the user and allows him to develop it. Perhaps, the reason for the superiority of the internet over other traditional means of communication is the possibility of change and transmission from one stage to another in a short period. This means that the internet is able to move from the use to the development of the use and then the development of means and innovation as the innovation of the internet is a logical product of the interaction of the user with the network. The internet invests all the proposals and ideas and does not ignore any even if it is simple. This is represented in social networking sites which in fact reflects personal emotio

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Publication Date
Fri Sep 15 2023
Journal Name
Al-academy
Employing digital marketing through communication in promoting the commercial product
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In recent years, the means of communication have achieved a great generality that made them occupy, in a short time, the first ranks among the most widely used social networks in the world, due to the many services and advantages offered by this network to its users. It has led to a leap in the field of visual communication, especially since it relies mainly on the image Its dimensions make it a means of communication and transfer of ideas and meanings between the peoples of the world, and it also allows the inclusion of digital advertising content using multimedia with a degree of professionalism in other social networks, which allowed the various segments of society the opportunity to invest this network in their businesses of differen

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Publication Date
Sat Jan 12 2019
Journal Name
Journal Of The College Of Education For Women
Volunteer Work in the Community Culture (Concepts - Forms - Controls - Goals)
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Perhaps one of the most pillars in building communities, and to achieve consistency between its members, is the volunteer work, he is a humanitarian exercise been closely associated with all the meanings of goodness and righteousness since ancient times, but it differs in size and shape and motivations and trends from one community to another, and from time to time; while at least in the stages of calm and stability, it increases in disasters and calamities and wars times, and perhaps (the popular crowd) is the best proof of that, they answered a call reference, and volunteered to defend their land and their holy places. In terms of form it may be donating money or effort or profession or otherwise, either in terms of the trend may be di

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