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Assessment <b></b>of Serum P53 Protein Level in Adult Patients with Acute Myeloid Leukemia in Correlation with Response to Treatment

Background: Acute myeloid leukemia (AML) is an adult leukemia characterized by rapid proliferation of undifferentiated myeloid precursors, leading to bone marrow (BM) failure and impaired erythropoiesis. The p53 tumor suppressor protein regulates cell division and inhibits tumor development by preventing cell proliferation of altered or damaged DNA. It orchestrates various cellular reactions, including cell cycle arrest, DNA repair, and antioxidant properties. Objectives: To investigate the relationship of P53 serum level with hematological findings, remission, and survival status in de novo AML patients. Methods: This is a cross-sectional study that enrolled 63 newly diagnosed de novo AML patients, and 15 sex- and age-matched healthy persons as a control group. Serum P53 levels were assessed using the enzyme-linked immunosorbent assay (ELISA) technique before initiating induction chemotherapy. The study was performed between November 2022 and May 2023 at the Hematology and Bone Marrow Transplant Center of the Medical City Complex in Baghdad. Results: There were significantly lower P53 serum levels in AML patients before starting chemotherapy compared to the control group. However, no substantial difference in P53 levels was identified between AML patients achieving complete remission and those exhibiting no response, nor between alive and deceased individuals. Furthermore, there was a positive yet statistically non-significant correlation between serum P53 levels and age, and no significant relationship between P53 levels and sex or various hematological parameters. Conclusion: P53 levels are low in AML patients. They are not associated with remission status or survival after six months and are not correlated with hematological values.

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Publication Date
Thu Aug 18 2022
Journal Name
Physica Scripta
NORM and hazard indices in soil and dates of palms groves in Baghdad Governorate, Iraq
Abstract<p>Date palm (Phoenix dactylifera) is one of the world’s oldest cultivated fruit crops and belongs to the Arecaceae family. It originated in Mesopotamia (Iraq) in 4000 BC. Large areas of palm groves in Iraq produce various types of dates for internal consumption and export. Their cultivation has spread and has become a significant crop in the Arabian Peninsula, North Africa, and the Middle East. Date fruits are widely consumed in Iraq, and radiological monitoring of this crop is necessary as activity concentrations of <sup>238</sup>U, <sup>232</sup>Th, <sup>40</sup>K, and <sup>137</sup>Cs were measured in 12 soil samples and 12 date samples from </p> ... Show More
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Publication Date
Tue Feb 28 2023
Journal Name
Iraqi Journal Of Science
Petrophysical Properties of Mauddud Formation in Selected Wells in Al-Ahdab Oil Field, Middle Iraq

       This paper aims to calculate the petrophysical properties in the Al-Ahdab field in the middle of Iraq within the Mauddud Formation. This study was based on the information available from well logs. The interactive petrophysical software IP (V4.5)  was used to calculate the porosity, hydrocarbon saturation and shale volume, divide the formation into reservoir units and buffer units, and evaluate these units in each well. The Mauddud was divided into five units, two of them were considered good reservoirs having good petrophysical properties (high porosity, Low water saturation, and low shale volume). The other three are not reservoirs because of poor petrophysical properties.

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Publication Date
Wed Aug 01 2018
Journal Name
Parasitology International
Genetic polymorphism of Baylisascaris procyonis in host infrapopulations and component populations in the Central USA

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Publication Date
Wed Dec 01 2021
Journal Name
Journal Of Arts Faculty Of Baghdad University
The Discourse of Christian Minority in Saad Hana's Novel "Abducted in Iraq": A Critical Perspective.

Publication Date
Fri Jun 01 2018
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
The role of Islamic banks in facing the financial crisis in Iraq from 2012-2014

The purpose of the research is to identify the role of Islamic banks in facing the financial crisis in Iraq for the period 2012-2014, and highlight the various factors that contributed to the emergence of the financial crisis, as well as to identify the problems and challenges facing the Islamic banking business in Iraq and identify the reasons and find appropriate solutions, And the development of treatments to avoid the occurrence of such problems and overcome them. The main findings of the research are as follows,Islamic banks (the sample of the study) were affected by the global financial crisis indirectly, as the financial crisis turned into an economic crisis affecting the real economy, because the activity of Islamic banks is more

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Publication Date
Thu Jun 15 2023
Journal Name
Journal Of Legal Sciences
Administrative Corruption in Contemporary Systems and the Role of Islamic Administrative Organization in Combating It

Administrative corruption is a concept that includes the abuse of entrusted power for personal benefit. It has become a prominent contemporary problem affecting all government systems around the world. It involves widespread harm and negative impact on progress and development, and is considered a threat at the international level because it impedes development programs and undermines the interests of the public. Administrative corruption threatens modern governments, distorts public policies, causes weaknesses in the oversight system, and affects the distribution of resources.

Islamic law is considered a pioneer in diagnosing this type of problem, as it provides clear solutions to eliminate administrative corruption, as Islamic

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Publication Date
Sun Sep 07 2014
Journal Name
Baghdad Science Journal
Determination of Copper and Lead and Study their Poisonous Effects in Drinking Water in Baghdad

The objective of this study is to determine the concentration of copper and lead (mg/L) in drinking water by using absorption spectrophotometic and Atomic Absorption spectrophotometric method from different area in Baghdad and with different intervals , The results show that the concentration of copper and Lead ( mgL) in tap water which remains motionless in plumbing system for following periods one hours, 3 hours, 6 hours, 12 hours, 24 hours, 7 days and 14 days are (1 , 2.2 , 4 , 5.3 , 7.5 , 10 and 16 mgL copper ) & ( 0.3, 0.5 , 0.8 , 1 , 2.5 , 3 , 3.8 mg /L lead ) respectively .from these results its clear that high levels of copper & Lead occur if tap water comes in contact with copper - lead plumbing and copper lead -containing fix

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Publication Date
Mon Apr 01 2019
Journal Name
Journal Of Legal Sciences
Criminal policy in the domain of freezing terrorist funds and its role in addressing crime

It emerged as the issue of counter - terrorism recently on international levels and internal as a result of the increase in terrorist acts and committed in various countries، resulting in loss of lives and money so concerned with countries in this issue and the need to combat and eliminate the negative destructive effects that have become affect the prestige and integrity of States and stability.

 As a result followed criminal legislation at the international and domestic incriminatory policy may be varied somewhat in order to confront terrorist crimes by criminalizing certain acts that constitute the crime of terrorist At the international level ، several global and regional international conventions held to combat this p

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Publication Date
Fri Dec 01 2023
Journal Name
Political Sciences Journal
¬The Role of the European Union in Conflicts Resolution in the Eastern Neighborhood: Selected Models

The launch of the EU’s Eastern Partnership in 2009 intended to signal a new, elevated level of EU engagement with its Eastern neighborhood. Yet there remain several long-simmering and potentially destabilizing conflicts in the region, with which EU engagement thus far has been sporadic at best. The Union’s use of its Common Security and Defense Policy (CSDP) in the region and to help solve these disputes has been particularly ad hoc and inconsistent, wracked by inter-institutional incoherence and undermined by Member States’ inability to agree on a broad strategic vision for engagement with the area.

The three CSDP missions deployed to the region thus far have all suffered from this incoherence to various extents. In particu

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Publication Date
Sun Oct 02 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Evaluation of Ionizing Radiation Protection among Radiation Workers in X-ray departments in Erbil City

Background: Ionizing radiations are hazardous agents in the workplace, since all forms of ionizing radiation produce some type of injury that is incurable. Therefore, protection against ionizing radiation exposure can play an important role in the health of workers.
Objectives: is to evaluate the application of radiation protection among radiation workers at X-ray department in Erbil hospitals.
Patients and methods: Six hospitals (General and Private) were visited. Samples of 110 were randomly selected among 135 radiation workers, 47 (42.3%) female and 63 (57.3%) male Data was collected through structured questionnaires. The surveyed data was coded and analyzed by using MS Excel software, and SPSS 18 f

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