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The unprejudiced of this education is to gauge the ability of the retinoic acid to induce apoptotic cell death
in hematological tumors through caspase dependent or independent apoptotic pathway, The cytotoxicity
effects of retinoic acid of different concentrations (400,350,300,250,200,150,100,50,25,12.5 μg\ml) and
exposure for all hematological malignancy cell lines (Human non-Hodgkin lymphoma SR and human
multiple myeloma (COLO 677) and Human Monocytic Leukemia THP1 and Acute promyelocytic leukemia
NB4) have been determined using a microtetrazolium (MTT) assay. Propodeum iodide and alcidine orange
(AO/PI) paired discoloration was used to study the ability of retinoic acid to induce apoptosis in the infected
cells and examined under fluore
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