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Small-molecule anticancer agents kill cancer cells by harnessing reactive oxygen species in an iron-dependent manner

In the course of generating a library of open-chain epothilones, we discovered a new class of small molecule anticancer agents that has no effect on tubulin but instead kills selected cancer cell lines by harnessing reactive oxygen species in an iron-dependent manner.

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Publication Date
Mon Mar 01 2021
Journal Name
Journal Of Physics: Conference Series
On Quasi-Small Prime Modules
Abstract<p>Let R be a commutative ring with identity, and W be a unital (left) R-module. In this paper we introduce and study the concept of a quasi-small prime modules as generalization of small prime modules.</p>
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Publication Date
Sun Mar 04 2018
Journal Name
Iraqi Journal Of Science
Fully Small Dual Stable Modules

New types of modules named Fully Small Dual Stable Modules and Principally Small Dual Stable are studied and investigated. Both concepts are generalizations of Fully Dual Stable Modules and Principally Dual Stable Modules respectively. Our new concepts coincide when the module is Small Quasi-Projective, and by considering other kind of conditions. Characterizations and relations of these concepts and the concept of Small Duo Modules are investigated, where every fully small dual stable R-module M is small duo and the same for principally small dual stable.

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Publication Date
Thu Jul 01 2021
Journal Name
Journal Of Physics: Conference Series
T-Small Quasi-Dedekind modules
Abstract<p>Let Q be a left Module over a ring with identity ℝ. In this paper, we introduced the concept of T-small Quasi-Dedekind Modules as follows, An R-module Q is T-small quasi-Dedekind Module if, <inline-formula> <tex-math><?CDATA $\forall \,w\,\in En{d}_{R}(Q),\,w\ne 0$?></tex-math> <math xmlns:mml="http://www.w3.org/1998/Math/MathML" overflow="scroll"> <mrow> <mo>∀</mo> <mspace width="0.25em"></mspace> <mi>w</mi> <mspace width="0.25em"></mspace> <mo></mo></mrow></math></inline-formula></p> ... Show More
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Publication Date
Wed Feb 22 2023
Journal Name
Iraqi Journal Of Science
Small Pointwise M-Projective Modules

Let R be a ring and let M be a left R-module. In this paper introduce a small pointwise M-projective module as generalization of small M- projective module, also introduce the notation of small pointwise projective cover and study their basic properties.
.

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Publication Date
Tue Feb 13 2024
Journal Name
Iraqi Journal Of Science
On δ-Small Projective Modules

Let be a commutative ring with unity and let be a non-zero unitary module. In
this work we present a -small projective module concept as a generalization of small
projective. Also we generalize some properties of small epimorphism to δ-small
epimorphism. We also introduce the notation of δ-small hereditary modules and δ-small
projective covers.

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Publication Date
Sat Apr 30 2022
Journal Name
Iraqi Journal Of Science
On Quasi-Small Prime Submodules

     Let  be a commutative  ring with identity , and  be a unitary (left) R-module. A proper submodule  of  is said to be quasi- small prime submodule  , if whenever   with  and , then either or . In this paper ,we give a comprehensive study of quasi- small prime submodules.

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Publication Date
Sun Mar 04 2018
Journal Name
Iraqi Journal Of Science
Essential-Small M-Projective Modules

In this paper, we introduce the concept of e-small M-Projective modules as a generalization of M-Projective modules.

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Publication Date
Fri Jul 19 2019
Journal Name
Iraqi Journal Of Science
On Jacobson – Small Submodules

Let R be an associative ring with identity and let M be a unitary left R–module. As a generalization of small submodule , we introduce Jacobson–small submodule (briefly J–small submodule ) . We state the main properties of J–small submodules and supplying examples and remarks for this concept . Several properties of these submodules are given . Also we introduce Jacobson–hollow modules ( briefly J–hollow ) . We give a characterization of J–hollow modules and gives conditions under which the direct sum of J–hollow modules is J–hollow . We define J–supplemented modules and some types of modules that are related to J–supplemented modules and int

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Publication Date
Sat Apr 15 2023
Journal Name
Iraqi Journal Of Science
Best Way to Detect Breast Cancer by UsingMachine Learning Algorithms

Breast cancer is the second deadliest disease infected women worldwide. For this
reason the early detection is one of the most essential stop to overcomeit dependingon
automatic devices like artificial intelligent. Medical applications of machine learning
algorithmsare mostly based on their ability to handle classification problems,
including classifications of illnesses or to estimate prognosis. Before machine
learningis applied for diagnosis, it must be trained first. The research methodology
which isdetermines differentofmachine learning algorithms,such as Random tree,
ID3, CART, SMO, C4.5 and Naive Bayesto finds the best training algorithm result.
The contribution of this research is test the data set with mis

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Publication Date
Mon Jan 01 2018
Journal Name
Blood Research
Relationship between liver iron concentration determined by R2-MRI, serum ferritin, and liver enzymes in patients with thalassemia intermedia

4 Blood Res 2018;53:314-319. Received on August 11, 2018 Revised on August 30, 2018 Accepted on August 30, 2018 Background Iron overload is a risk factor affecting all patients with thalassemia intermedia (TI). We aimed to determine whether there is a relationship of serum ferritin (SF) and alanine ami- notransferase (ALT) with liver iron concentration (LIC) determined by R2 magnetic reso- nance imaging (R2-MRI), to estimate the most relevant degree of iron overload and best time to chelate in patients with TI. Methods In this cross-sectional study, 119 patients with TI (mean age years) were randomly se- lected and compared with 120 patients who had a diagnosis of thalassemia major (TM). Correlations of LIC, as determined by R2-MRI, with SF

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