Coumarins have been recognized as anticancer competitors. HDACis are one of the interesting issues in the field of antitumor research. In order to achieve an increased anticancer efficacy, a series of hybrid compounds bearing coumarin scaffolds have been designed and synthesized as novel HDACis, In this review we present a series of novel HDAC inhibitors comprising coumarin as a core e of cap group of HDAC inhibitors that have been designed, synthesized and assessed for their enzyme inhibitory activity as well as antiproliferative activity. Most of them exhibited potent HDAC inhibitory activity and significant cytotoxicity
The lossy-FDNR based aclive fil ter has an important property among many design realizations. 'This includes a significant reduction in component count particularly in the number of OP-AMP which consumes power. However the· problem of this type is the large component spreads which affect the fdter performance.
In this paper Genetic Algorithm is applied to minimize the component spread (capacitance and resistance p,read). The minimization of these spreads allow the fil
... Show MoreFuzzy Based Clustering for Grayscale Image Steganalysis
Image retrieval is an active research area in image processing, pattern recognition, and
computer vision. In this proposed method, there are two techniques to extract the feature
vector, the first one is applying the transformed algorithm on the whole image and the second
is to divide the image into four blocks and then applying the transform algorithm on each part
of the image. In each technique there are three transform algorithm that have been applied
(DCT, Walsh Transform, and Kekre’s Wavelet Transform) then finding the similarity and
indexing the images, useing the correlation between feature vector of the query image and
images in database. The retrieved method depends on higher indexing number. <
Skull image separation is one of the initial procedures used to detect brain abnormalities. In an MRI image of the brain, this process involves distinguishing the tissue that makes up the brain from the tissue that does not make up the brain. Even for experienced radiologists, separating the brain from the skull is a difficult task, and the accuracy of the results can vary quite a little from one individual to the next. Therefore, skull stripping in brain magnetic resonance volume has become increasingly popular due to the requirement for a dependable, accurate, and thorough method for processing brain datasets. Furthermore, skull stripping must be performed accurately for neuroimaging diagnostic systems since neither no
... Show MoreIn this paper an algorithm for Steganography using DCT for cover image and DWT for hidden image with an embedding order key is proposed. For more security and complexity the cover image convert from RGB to YIQ, Y plane is used and divided into four equally parts and then converted to DCT domain. The four coefficient of the DWT of the hidden image are embedded into each part of cover DCT, the embedding order based on the order key of which is stored with cover in a database table in both the sender and receiver sender. Experimental results show that the proposed algorithm gets successful hiding information into the cover image. We use Microsoft Office Access 2003 database as DBMS, the hiding, extracting algo
... Show MoreThe feature extraction step plays major role for proper object classification and recognition, this step depends mainly on correct object detection in the given scene, the object detection algorithms may result with some noises that affect the final object shape, a novel approach is introduced in this paper for filling the holes in that object for better object detection and for correct feature extraction, this method is based on the hole definition which is the black pixel surrounded by a connected boundary region, and hence trying to find a connected contour region that surrounds the background pixel using roadmap racing algorithm, the method shows a good results in 2D space objects.
Keywords: object filling, object detection, objec
Detection moving car in front view is difficult operation because of the dynamic background due to the movement of moving car and the complex environment that surround the car, to solve that, this paper proposed new method based on linear equation to determine the region of interest by building more effective background model to deal with dynamic background scenes. This method exploited the permitted region between cars according to traffic law to determine the region (road) that in front the moving car which the moving cars move on. The experimental results show that the proposed method can define the region that represents the lane in front of moving car successfully with precision over 94%and detection rate 86
... Show MoreEmotion recognition has important applications in human-computer interaction. Various sources such as facial expressions and speech have been considered for interpreting human emotions. The aim of this paper is to develop an emotion recognition system from facial expressions and speech using a hybrid of machine-learning algorithms in order to enhance the overall performance of human computer communication. For facial emotion recognition, a deep convolutional neural network is used for feature extraction and classification, whereas for speech emotion recognition, the zero-crossing rate, mean, standard deviation and mel frequency cepstral coefficient features are extracted. The extracted features are then fed to a random forest classifier. In
... Show MoreClustering algorithms have recently gained attention in the related literature since
they can help current intrusion detection systems in several aspects. This paper
proposes genetic algorithm (GA) based clustering, serving to distinguish patterns
incoming from network traffic packets into normal and attack. Two GA based
clustering models for solving intrusion detection problem are introduced. The first
model coined as handles numeric features of the network packet, whereas
the second one coined as concerns all features of the network packet.
Moreover, a new mutation operator directed for binary and symbolic features is
proposed. The basic concept of proposed mutation operator depends on the most
frequent value
Classification of network traffic is an important topic for network management, traffic routing, safe traffic discrimination, and better service delivery. Traffic examination is the entire process of examining traffic data, from intercepting traffic data to discovering patterns, relationships, misconfigurations, and anomalies in a network. Between them, traffic classification is a sub-domain of this field, the purpose of which is to classify network traffic into predefined classes such as usual or abnormal traffic and application type. Most Internet applications encrypt data during traffic, and classifying encrypted data during traffic is not possible with traditional methods. Statistical and intelligence methods can find and model traff
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