Plasma-assisted desorption ionization-mass spectrometry
optimization
ibuprofen
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In medical practice, nonsteroidal anti-inflammatory drugs (NSAIDs) are often used to treat
osteoarthritis and rheumatoid arthritis. Ibuprofen is a well-known NSAID, analgesic, and
antipyretic medication. This chemical is an active ingredient of several oral medications that
are offered in tablet, gel pellet, and syrup forms and has higher efficacy, tolerance, and side effect rates than other compounds, including pyrazolone derivatives. We present a unique plasma-assisted desorption/ionization mass spectrometry (PADI-MS) approach for improving pharmaceutically important solids using an ibuprofen tablet as a model solid sample. The goal of
the study is to create an innovative mass spectrometric method that could be used for quick
and accur
...
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