Rheumatoid arthritis (RA) is an inflammatory condition causing joint pain and stiffness, with often debilitating and life-limiting consequences. Recently, a new B-cell secreted cytokine, IL-39, was identified in mice. The most up-to-date research indicates that although IL-39 is expressed in murine models of lupus and has a role in mediating the inflammatory response in this context, there is no solid, replicated evidence of the existence of IL-39 in humans. This study aimed to clarify the existence and role of IL-39 in the human body and to elucidate whether it plays a role in rheumatoid arthritis. Accordingly, serum samples were collected from 66 patients with rheumatoid arthritis who were under therapy and from 66 healthy c

Objective Thalassemic patients present with multiple immune abnormalities that may predispose them to oral Candida, however this has not been investigated. The aim of this study was to assess oral candidal colonization in a group of patients with β-thalassemia major both qualitatively and quantitatively. Study design The oral mycologic flora of 50 β-thalassemia major patients and 50 age- and sex-matched control subjects was assessed using the concentrated oral rinse technique. Candida species were identified using the germ tube test and the Vitek yeast identification system. Results Oral Candida was isolated from 37 patients (74%) and 28 healthy subjects (56%; P = .04). The mean candidal count was significantly higher in thalassemic patie

The sustainable development according to the United Nation, listed firms throughout globally now routinely provide sustainability data. However, there is not enough information on Sustainability Performance Quality (SPQ) in the majority of emerging economies, including Malaysia. This study looks at how the SPQ of the top 100 Malaysian-listed businesses is affected by factors as connected with corporate governance (e.g., board meeting, board size, and board ethnic diversity). Utilizing 500 firm-year data, a longitudinal sample of 500 nonfinancial firms on the Bursa Malaysia for 2015-2019 is employed in this study. The findings from the analysis using the panel regression demonstrated that: ethnic diversity and board siz

Missing data is one of the problems that may occur in regression models. This problem is usually handled by deletion mechanism available in statistical software. This method reduces statistical inference values because deletion affects sample size. In this paper, Expectation Maximization algorithm (EM), Multicycle-Expectation-Conditional Maximization algorithm (MC-ECM), Expectation-Conditional Maximization Either (ECME), and Recurrent Neural Networks (RNN) are used to estimate multiple regression models when explanatory variables have some missing values. Experimental dataset were generated using Visual Basic programming language with missing values of explanatory variables according to a missing mechanism at random general pattern and s

Background Subtraction (BGS) is one of the main techniques used for moving object detection which further utilized in video analysis, especially in video surveillance systems. Practically, acquiring a robust background (reference) image is a real challenge due to the dynamic change in the scene. Hence, a key point to BGS is background modeling, in which a model is built and repeatedly used to reconstruct the background image.

From N frames the proposed method store N pixels at location(x,y) in a buffer, then it classify pixel intensity values at that buffer using a proposed online clustering model based on the idea of relative  run length, the cluster center with the highest frequency will be adopted as the background pixel