Rheumatoid arthritis is an autoimmune diseasecharacterized by chronic inflammationthat affects joints and cartilage. Bone complications such asRA-relatedosteoporosis are one of the most extra-articular manifestations. Many inflammatory mediators are released during RA disease pathophysiology; these mediators stimulate osteoclast genesis of bone by direct effects on RANKL and OPG. The study aimedto measure RANKL, OPG in RA patients treated with Etanercept only and other groups treated with Methotrexate onlyat baseline and after three months to evaluate bone state. An observational case-control prospective study was done on 30 RA patients who received MTX, 30 RA patients who received ETN, and 30 healthy,age-matched control groups. The level of RANKL and OPG was measured at baseline and after three months of therapy by immunoenzymatically assay (ELISA). The results were tabulated and statistically analyzed usingthe statistical package for social science. The result demonstrated that RANKL level had a positive correlation with age and disease duration in contrast to OPG level showed a negative correlation with age and duration of disease. In the patients group treated with MTX at baseline, the RANKL level was significantly higher (181.336±65.583) than post-therapy (166.097±69.229), while the OPG level at baseline significantly lower (594.398±133.238) than post therapy (614.499±150.879). In ETN treated patients, the level of RANKL in baseline was significantly higher than (231.247±73.134) RANKL level post-therapy (200.363±76.807), while OPG level in baseline waslower (463.263±96.392) than post therapy (503.608±107.692). The study demonstrated in baseline RANKL/OPG ratio significant higher (0.4340±0.234) than post therapy (0.3690±0.222). All RA patients had or were at high risk for osteoporosis.Both Etanarcept and methotrexate produce insignificant differences on OPG and RANKL levels, in the same time this biomarkers are not good indicators for bone state.
For aspirin estimated, a molecularly imprinted polymer MIP-ASP electrodes were generated by electro-polymerization process, the electrodes were prepared by combining the template (aspirin) with (vinyl acetate (VA), 1-vinylimidizole (VIZ) as a functional monomer and N, N-methylene bisacrylamide (MBAA) as crosslinkers using benzoyl peroxide (BPO) as an initiator. The efficiency of the membrane electrodes was analyzed by differential pulse voltammetry (DPV). Four electrodes were synthesized using two different plasticizers, di-butyl sebacate (DBS), di-octyl phthalate (DOP) in PVC matrix. Scanning electron microscopy (SEM) was used to describe the generated MIP, studying the electrodes properties, the slope, detection limit, and life
... Show MoreThe importance of topology as a tool in preference theory is what motivates this study in which we characterize topologies generating by digraphs. In this paper, we generalized the notions of rough set concepts using two topological structures generated by out (resp. in)-degree sets of vertices on general digraph. New types of topological rough sets are initiated and studied using new types of topological sets. Some properties of topological rough approximations are studied by many propositions.
The research is concerned with the problems of knowledge purification of kindergarten children by verifying its aims, identifying of knowledge purification among the first level of kindergarten children and the second level of kindergarten children, and the differences between the males and females in the variable of knowledge purification. The research community included the children in the state and private kindergartens in Baghdad governorate, on its two sides, Karkh and Rusafa, for the six districts for the academic year 2022-2023. After making the knowledge purification test according to the scientific steps of test constructions, the test has been presented to a group of experts specialized in the field of kindergarten to ascertain
... Show MoreThe researcher found that neglecting our Arab Islamic heritage and bragging about what the West came in the field of education and psychology is common in our curriculum
So the researcher found it necessary to identify the thought of our media Arab Muslims like Ibn Al-Jawzi being a remarkable figure in the world of human thought therefore, the researcher in this research decided to identify his educational and psychological ideas and psychological emotions in his mind and methods of control and characteristics of the human soul and methods of development of the Muslim character by following the descriptive analytical approach.
Shoot tip of Actinidia chinensis plant were excised and sterilized with mercuric chloride (Hgcl2) at concentration 0.1% for 5 min, then cultured on MS medium supplemented with benzeladinine BA at concentration (0.0,0.5,1.0,2.0,2.5) mg/l in multiplication stage Moreover, indole butyric acid IBA at concentration (0.0, 0.5,1.0,2.0,4.0) mg/l and (0.0,0.5,1.0,2.0) mg/l on solid and liquid solution media respectively in rooting stage were studied. All experiments have done under controlled conditions (25 ±2) Cº and 1000Lux light intensity for 16 hrs / day. Results revealed that supplementing the media with BA at concentrations 2.0 and2.5 mg/l was superior to give highest rate of shoot and number of leaves reached 5.8 /explant and 6.0 l
... Show MoreA mathematical model and associated computer program were developed to simulate the steady state operation of wiped film evaporators for the concentration of glycerol-water solution. In this model, various assumptions were made to facilitate the mathematical model of the wiped film evaporator. The fundamental phenomena described were: sensible heating of the solution and vaporization of water. Physical property data were coded into the computer program, which performs the calculations of this model. Randomly selected experiments were carried out in a small scale wiped film evaporator from ALVAL COMPANY, using different concentrations of the glycerol solution (10, 30 and 50 Wt. %) for different feed rates (30, 50, 80, 100 and 120 l/h) and
... Show MoreThe aims of this thesis are to study the topological space; we introduce a new kind of perfect mappings, namely j-perfect mappings and j-ω-perfect mappings. Furthermore, we devoted to study the relationship between j-perfect mappings and j-ω-perfect mappings. Finally, certain theorems and characterization concerning these concepts are studied. On the other hand, we studied weakly/ strongly forms of ω-perfect mappings, namely -ω-perfect mappings, weakly -ω-perfect mappings and strongly-ω-perfect mappings; also, we investigate their fundamental properties. We devoted to study the relationship between weakly -ω-perfect mappings and strongly -ω-perfect mappings. As well as, some new generalizations of some definitions wh
... Show MoreFor the generality of fuzzy ideals in TM-algebra, a cubic ideal in this algebra has been studied, such as cubic ideals and cubic T-ideals. Some properties of these ideals are investigated. Also, we show that the cubic T-ideal is a cubic ideal, but the converse is not generally valid. In addition, a cubic sub-algebra is defined, and new relations between the level subset and a cubic sub-algebra are discussed. After that, cubic ideals and cubic T-ideals under homomorphism are studied, and the image (pre-image) of cubic T-ideals is discussed. Finally, the Cartesian product of cubic ideals in Cartesian product TM-algebras is given. We proved that the product of two cubic ideals of the Cartesian product of two TM-algebras is also a cubic ideal.
