Reducing the negative effects of non-compliance and unethical behaviour by adopting the risk approach to human resources management
(6)
Publication Date
Tue May 20 2025
Journal Name
Vrsacin Deae-cellulose Linezolid Neutrophils Inflammation
Antibacterial and therapeutic effects of vancomycin-resistant
Staphylococcus aureus bacteriocin (VRSAcin) in the treatment of VRSA skin infection in mice
VRSAcin
DEAE-Cellulose
Linezolid
Neutrophils
Inflammation
Vancomycin Staphylococcus aureus (VRSA) is a strain of S. aureus that is considered the main cause of bacterial skin and soft tissue infections. It has acquired resistance to vancomycin and represents a therapeutic challenge. The current study aimed to compare the possible therapeutic effects of VRSA bacteriocin (VRSAcin) on the treatment of skin infection in mice with those of an antibiotic (linezolid). The results showed that of the fifty swabs obtained from human skin wounds. One isolate was selected for VRSAcin extraction depending on its antibiotic resistance using an antibiotic susceptibility test.An agar well diffusion test was used to determine bacteriocin’s antibacterial activity, as well as its a minimum inhibitory concentration
... Show MorePublication Date
Fri Aug 01 2025
Journal Name
Microbial Pathogenesis
Antibacterial and therapeutic effects of vancomycin-resistant Staphylococcus aureus bacteriocin (VRSAcin) in the treatment of VRSA skin infection in mice
Vancomycin Staphylococcus aureus (VRSA) is a strain of S. aureus that is considered the main cause of bacterial
skin and soft tissue infections. It has acquired resistance to vancomycin and represents a therapeutic challenge.
The current study aimed to compare the possible therapeutic effects of VRSA bacteriocin (VRSAcin) on the
treatment of skin infection in mice with those of an antibiotic (linezolid). The results showed that of the fifty
swabs obtained from human skin wounds. One isolate was selected for VRSAcin extraction depending on its
antibiotic resistance using an antibiotic susceptibility test.An agar well diffusion test was used to determine
bacteriocin’s antibacterial activity
as well as its a minimum inhibitory concentration
minimum bactericidal
concentration
and antibiofilm efficiency against gram-positive and gram-negative bacteria that were resistant to
many medicines. The freshly developed antibacterial substance VRSAcin shows promise. Bacteriocin from VRSA
was extracted and studied the optimal conditions for the Production following Purification of bacteriocin by
ammonium sulfate precipitation followed by cation-exchange chromatography. The molecular weight of
bacteriocin about (29 kDa) were determined by Sodium Dodecyl Sulfate-polyacrylamide gel electrophoresis
(SDS-PAGE). The typical conditions for the production of VRSAcin include a pH of 7 and a temperature of 37 ◦C
for 48 h. In mice
VRSA-contaminated wounds revealed severe tissue distraction and inflammation that extended
to the hypodermis
while VRSA-treated skin showed mild changes and localized lesions to the epidermis and
upper dermis. The skin of linezolid ointment-treated mice showed moderate to severe changes. In conclusion
VRSA strain infections in human burned skin were more common than expected. In vivo studies in mice indicated
that wounded skin infected with VRSA can be treated with VRSAcin as an antibacterial agent that promotes
healing processes with obvious superiority to linezolid ointment. As a result
the VRSA develops bacteriocins that
are appropriate for regulating AMR
Gram-positive and Gram-negative bacteria
and may be useful in wound
dressings.
(5)
(4)
Publication Date
Wed Mar 28 2018
Journal Name
Indian Journal Of Natural Sciences
Publication Date
Sun Jun 21 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Evaluation the Incidence of Genotoxic Effects of Artificial Food Favoring Additives in Bone Marrow Cells and Spleen Cells in Mice
Artificial food flavoring additive
bone marrow cells
spleen cells
genotoxicity
chromosome
Genetic material is the most important component of cells because it contains the genetic information; hence any disruption to the structure chromosome of cells could lead to very bad results. Genotoxicity use to evaluate the safety of any chemical compounds on genetic materials. Artificial food flavoring additive are chemical substances to produce specific placebo effects added to foods but impart specific flavor to it.
The present study evaluates the genotoxic effect of artificial food flavoring additive on structure of chromosomes at three different concentrations (50%, 100%and 150%) on both bone marrow cells and spleen cells in mice for fourteen successive days. It was found that artificial food flavoring addit
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(1)
Publication Date
Tue Jan 01 2019
Journal Name
Indian Journal Of Public Health Research & Development
Effects of Artificial Aging on Some Properties of Room-Temperature-Vulcanized Maxillofacial Silicone Elastomer Modified by Yttrium Oxide Nanoparticles
maxillofacial silicone
Y2O3
nanoparticles
fllers
artificial aging.
Abstract Background: The daily usage of maxillofacial prostheses causes them to mechanically deteriorate with time. This study was aimed to evaluate the reinforcement of VST50F maxillofacial silicone by using yttrium oxide (Y2O3) nanoparticles (NPs) to resist aging and mechanical deterioration. Materials and Method: Y2O3 NPs (30–45nm) were loaded into VST50F maxillofacial silicone in two weight percentages (1 and 1.5 wt%), which were predetermined in a pilot study as the best rates for improving tear strength with minimum increase in hardness values. A total of 120 specimens were prepared and divided into the control and experimental groups (with 1 and 1.5 wt% Y2O3 addition). Each group included 40 specimens, 10 specimens for each paramet
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(4)
(4)
Publication Date
Fri Nov 01 2019
Journal Name
Iop Conference Series: Earth And Environmental Science
The Role of Sewage Irrigation Management in Water Productivity, Growth and Yield Parameters of Broccoli in Al-Sulaimani government/Kurdistan region
Abstract<p>The objective of the present work was to estimate water requirements and water use efficiency for Broccoli under normal irrigation conditions and sewage irrigation. Field experiment was carried out during the season 2018 at station/Sulaimni agricultural station/Bakrajo –College of Agricultural Sciences. The experiment included three treatments: River water irrigation in all season growth (I<sub>1</sub>), Sewage water irrigation in all season growth (I<sub>2</sub>), Alternate irrigation (one river irrigation followed by two sewage water irrigation) in all season growth (I<sub>3</sub>). The experimental Design was Randomized Complete Block Design (RCBD) w</p>
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(1)
Publication Date
Sun Jun 06 2010
Journal Name
Baghdad Science Journal
Preparation of Media for Growth and Isolation of Lactic Acid Bacteria by Using the Starch-Industry by- Products
By- products of corn starch industry were used to prepare media for propagation the lactic acid bacteria as a natural auxotroph. The by- products used were the corn steep water (S) and gluten extract (G) after a proper treatment to get them ready for media preparation. The results showed that it was possible to replace the peptone and meat extract by gluten extract in MRS medium. The growth was approximately similar to that obtained in standard MRS media. Corn steep water (S) was used as well and the growth enhanced by including Tween – 80 at 1% level. The later media named MZ, which was superior for growing standard and local strains and starters. The MZ medium modified by adding acetate and glacial acetic acid similarly to
... Show More
Publication Date
Thu Apr 01 2021
Journal Name
Iop Conference Series: Earth And Environmental Science
A Vision to Develop the Effectiveness of the Dissemination of Innovations to Rationalize the Use of Irrigation Water in Iraqi Agriculture
Abstract<p>Iraqi agriculture faces a major water problem, affecting cultivated areas, agricultural production, farmers’ incomes and food security. However, the results achieved in rationalizing the use of irrigation water are still limited and do not match what they should be in order to meet this serious challenge. The study aimed to provide a vision for the development of the effectiveness of the dissemination of innovations to rationalize the use of irrigation water in Iraqi agriculture. In light of the framework of the dissemination of agricultural innovations, factors related to their effectiveness, and the summary of the Iraqi experience in the field of dissemination of modern irrigation</p>
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Vision
Development
Effectiveness
Dissemination
Innovations
Rationalize
Irrigation water
(4)
Publication Date
Tue Jan 01 2019
Journal Name
Izvestiya Of Saratov University. New Series. Series: Philology. Journalism
Publication Date
Wed Feb 02 2022
Journal Name
Elementary Education Online
the power of the federal supreme court to stop the implementation of the law
constituition - endowment - federal court - iraq - law
the power of the federal supreme court to stop the implementation of the law