It is becoming a public health issue to predict which expectant women will develop gestational diabetes mellitus (GDM). The goal of this case control research is to investigate the role of maternal oxidative stress levels in the first, second, and third trimesters, as well as other factors, in the development of gestational diabetes mellitus (GDM).
Methods
Between October and December 2021, 142 women participated in this research. The 101 GDM patients were split into three groups based on their gestation (T1, T2, and T3), and 41 healthy pregnant women were chosen as the comparison group. TAS and TOS levels of oxidative stress and XO were calculated using a Spectrophotometer for colorimetric techniques; fasting and random sugar levels, as well as HbA1c, were evaluated.
Results
Afamin levels were significantly greater in women with GDM in all trimester (T1=51.63 ± 3.86, T2=57.39 ± 3.17, T3=64.22 ± 3.67 ng/mL) in comparison with control (45.93 ± 2.26) with statistical significance (P ≤ 0.01). Afamin levels were higher significantly in T3>T2>T1.The levels of oxidative stress were higher significantly in women with GDM in all trimester (T1=73.79 ± 18.43, T2=81.28 ± 18.06, T3=96.70 ± 20.69) in comparison with control (37.28 ± 18.95) with statistical significance (P = 0.000). Oxidative stress levels were higher significantly in T3>T2>T1. The measured TOS and XO levels were  higher in all GDM groups compared with control (p=0.000) and high significant between patient groups (T3>T2>T1), while high significant of TAS in GDM than control but (T3
Background Over the past decade there has been a growing awareness of, and interest in, the trace element concentration differences between normal and diseased tissues. Significant changes in tissue concentrations of Zinc (Zn) and Copper (Cu) have been previously reported in inflammation and cancer of certain human tissues.
Aim:(1)To correlate between Zn and Cu concentrations and the histological picture of normal and certain inflamed human tissues, namely the gall bladder (GB) the vermiform appendix (VA), visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT). (2) to detect whether there is a difference in the above-mentioned parameters between VAT and SAT. (3) to obtain recordings for trace element levels in human tissu
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