Cataract is an opacity in the normally transparent focusing lens of the eye which leads to blindness. The aim of current study is to investigate the possible protective and therapeutic effects of aqueous extract of Foeniculum vulgare seed eye drops (0.5%) against selenite induced cataract in rabbits. Aqueous extract of Foeniculum vulgare seed prepared then formulated as eye drops. Sodium selenite used to induce cataract in rabbits' right eye by single intravitreal injection. Thirty-six rabbits included in the study and divided into three equal groups (12 rabbits in each group): healthy control group, Cataract-Induced group and group treated by Foeniculum vulgare seed extract eye drops. Parameters include the score of lens opacity which was determined by using an ophthalmoscope, pupillary response to light, pupil diameter, Corneal sensation, Conjunctival redness, intraocular pressure (IOP) measurement, malondialdehyde (MDA) level in aqueous humor and scanning electron microscope (SEM) image of the eye lens. The results of this study revealed that eye drop of Foeniculum vulgare seed extract was highly significantly reduced the mean of lens opacity score in comparison with cataract-induced group after two weeks of cataract induction (p< 0.01). MDA level of the group treated with Foeniculum vulgare seed extract eye drops was highly significant less than the MDA level of cataract-induced group (p< 0.01). SEM image of rabbit's lens treated by Foeniculum vulgare seed extract eye drops shows normal appearances of the eye lens. in conclusion, eye drops prepared from aqueous extracts of Foeniculum Vulgare seed had protective and …
The effect of the aqueous extract of fenugreek seeds (Trigonella Foenum Graecum L.), Rhodium complex (?) with formula [RhL2CLH2O].1 1/2 ETOH and palladium (?) [pdl2].2ETOH,where L=2-hydroxy phenyl piperonalidine was studied on two cancer cell lines. The first cell line was intestine cancer of female albino mice (L20B), the second one was Rhabdomysarcomas (RD)cell line in human. The activity of the new complexes and the aqueous extract was compared to the well-known anticancer drug (cis-platin) by utilizing the in vitro system. The cell lines were treated with four concentrations of cis-platin 31.25,62.5,125 and 250 ?g/ml for 72 hour exposure time. The same concentrations were used with extract and the new complexes. This study showed that t
... Show MoreThis work was conducted to study the oxidation of phenol in aqueous solution using copper based catalyst with zinc as promoter and different carrier, i.e. γ-Alumina and silica. These catalysts were prepared by impregnation method.
The effect of catalyst composition, pH (5.6-9), phenol to catalyst concentration ratio (2-0.5), air feed rate (30-50) ml/s, stirring speed (400-800) rpm, and temperature (80-100) °C were examined in order to find the best conditions for phenol conversion.
The best operating conditions which lead to maximum phenol conversion (73.1%) are : 7.5 pH, 4/6 phenol to catalyst concentration, 40 ml/s air feed rate, 600 rpm stirring speed, and 100 °C reaction temperature. The reaction involved an induction period
In Iraq; there is a great demand for handling some epidemic diseases such as hyperglycemia and hyperlipidema through searching some medical plant extracts which the country is rich with and contains an important phytochemicals that may solve the incidence of such cases. Aloe vera that cultivated in Iraq, is known to be rich with biological active constituents. The aim of the present study; the plant gel extract was subjected to treat an induced diabetic lab mice through injecting streptozotocin dose with high fatty food to elevate lipid profile before induction of the gel oral treatment of the plant. In the study results: the oral administration of A.ver
... Show MoreThe crude aqueous extract of menthespicata , the objective of this study was to investigate the effects of this extraction , on the histological changes of the ovares and levels of sex hormone , ( FSH , LH , Estradiol ) in albino female mice . the extract was given orally for( 45 ) days . fourty mature female mice were used in this study , the animals divided into four major groups . each group was include ten mice . the first three groups was given different concentration )) (21 , 14 , 7 %) . While the fourth group considered as control group which had been administrated tab water . For ( 45 ) days each group had been killed for hormonal assay in blood
... Show MoreCancer stay to be one of the leading causes of death throughout the world due to a limited success to use treatments. The new synthesized metal complexes with formula: [Ni L2 (H2O)2]. 2.5 E t OH and [Cd L2]. ½ H2O Where L = Bis [ 5 – ( P – nitrophenyl ) - 4 – phenyl 1 , 2 , 4 – trazol – 3 – dithiocarbamato hydrazide ] and the aqueous extract of Teucrium polium L.(TP) plant (Ja,adahin Arabic) were examined against growth cells of hepatocellular Carcinoma cell Line ( HeP2 ). The cytotoxicity assay of cancer cell line was used for determination of inhibition rate with three concentrations; (62.5, 105 and 250 µg /200µl). The aqueous extract of TP plant induced death of cancer cells by significant elevation of the inhib
... Show MoreBackground: The rhizome of ginger is used in cooking and for medicinal purposes such as anti-bacterial, anti-fungal, anti-inflammatory and antioxidant. The aims of the study were to test the effect of ethanolic extract of ginger on growth, adherence and acidogenicity of mutans streptococci in comparison to chlorhexidine gluconate 0.2% and de-ionized water. Materials and methods: From saliva often volunteers (dental students 20-22 years); mutans streptococci was isolated, purified and diagnosed according to morphological characteristic and biochemical tests. Ginger was powdered and extracted, different concentrations of ginger extract were prepared. Chlorhexidine gluconate 0.2% used as a control positive; while de-ionized water was used as a
... Show MoreThe study conducted to investigate the association between Helicobacter pylori infection and eye diseases (Glaucoma, Cataract, CSR and Uveitis). One hundred and four patients with multiple eye disorders (10-80) years were observed from 10/9 to 18/11/2020 and compared to thirty-one healthy people (19 female and 12 male). Both participants were tested for anti-H. pylori IgA, and IgG antibodies using ELISA. There were non –significant differences (P≥0.05) in the concentration of anti-H. pylori IgA Abs in sera of patients with Glaucoma, CSR, and Uveitis compared to the control group, but there was a significant difference (P≤0.05) in the concentration of H. pylori IgA Abs in sera of patients with Cataract compared to the control group and
... Show MoreThe present study is undertaken to evaluate the effects of hypothyroidism induced by carbimazol in male rat reproductive system. Rats were treated with carbimazol (80 and 160 mg/kg body weight) daily for two, four, six, and eight weeks, while control rats were given distilled water orally. The results of these experiments are: 1-Treatment with carbimazol produced increase in body weight of treated animals. This increase was not statistically significant even at high concentrations. 2-Decrease in testicular weight was observed during all administration points. This decrease was aggravated proportional to duration and dose (p≤0.001). 3-Results of most intervals showed significant decrease in epididymal-head weight, while no sig
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