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Effect of Foeniculum vulgare seed aqueous extract eye drops on selenite induced cataract in rabbits

Cataract is an opacity in the normally transparent focusing lens of the eye which leads to blindness. The aim of current study is to investigate the possible protective and therapeutic effects of aqueous extract of Foeniculum vulgare seed eye drops (0.5%) against selenite induced cataract in rabbits. Aqueous extract of Foeniculum vulgare seed prepared then formulated as eye drops. Sodium selenite used to induce cataract in rabbits' right eye by single intravitreal injection. Thirty-six rabbits included in the study and divided into three equal groups (12 rabbits in each group): healthy control group, Cataract-Induced group and group treated by Foeniculum vulgare seed extract eye drops. Parameters include the score of lens opacity which was determined by using an ophthalmoscope, pupillary response to light, pupil diameter, Corneal sensation, Conjunctival redness, intraocular pressure (IOP) measurement, malondialdehyde (MDA) level in aqueous humor and scanning electron microscope (SEM) image of the eye lens. The results of this study revealed that eye drop of Foeniculum vulgare seed extract was highly significantly reduced the mean of lens opacity score in comparison with cataract-induced group after two weeks of cataract induction (p< 0.01). MDA level of the group treated with Foeniculum vulgare seed extract eye drops was highly significant less than the MDA level of cataract-induced group (p< 0.01). SEM image of rabbit's lens treated by Foeniculum vulgare seed extract eye drops shows normal appearances of the eye lens. in conclusion, eye drops prepared from aqueous extracts of Foeniculum Vulgare seed had protective and …

Publication Date
Sun Sep 07 2008
Journal Name
Baghdad Science Journal
Effect of sulphur on soil pH, growth and productivity of rape seed plant

A field trial was conducted in Experimental Station of The Field Crops Department – College Of Agriculture In Abu Ghraib, University of Baghdad to assess the effect of sulphur applications and the time after application on pH and EC of soil sample solutions ,and on the growth and yield of rape seed (Brassica napus L.)A split plot design was used with four replications , The main plot included four sulphur applications levels (0,2000,3000,4000Kg S/ha) the sub plot were the time after application (0,1,2,and 3 moths) .Sulphur application significantly decreased soil pH value ,although that decrease reached minimum parameter after two months from application date .Rather increment of sulphur application level significantly raised soil EC val

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Publication Date
Wed Jan 01 2014
Journal Name
Int. J. Adv. Res
Antibacterial activity of parsley and celery aqueous extract on the isolated bacteria from children UTI in Erbil city‏

Publication Date
Thu Jun 23 2022
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Effect of Curcumin at Various Doses on the Pharmacokinetic Profile of Tacrolimus in Healthy Rabbits

The purpose of present study is to evaluate the effect of co-administration of curcumin (CUR) at various doses on the pharmacokinetic (PK) profile of tacrolimus (TAC), a CYP 3A4 substrate in healthy male rabbits. Healthy male rabbits (n=18) were employed in an in vivo, parallel-randomized study. Three groups of rabbits were selected and separated: The rabbits in the first group (control group) received 1 mg/kg TAC orally. Blood samples (1.5-2 mL) were drawn from rabbits' ear marginal veins at the following time frames:  15.0, 30.0, 45.0, 60.0, 90.0, 120.0, 150.0, 180.0 and 300 minutes after TAC administration post dosing and analyzed by using a TAC chemiluminescent enzyme immunoassay (CLIA) detection kit. In the second and third gro

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Publication Date
Sun Jul 04 2010
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The Effect of Exposure to Formaldehyde Vapor on the Structure of Testes in the Rabbits.

Background: This study has been performed to detect any structural changes in the testes of rabbits that have been exposed to formaldehyde vapor.
Materials and Methods: Eighteen male rabbits has been used in this study, 12 of them were exposed to formalin vapor for 2 month, while the other 6 were exposed to the vapor of distilled water for 2 month too. All animals were killed at the end of experiments, and then pieces of testes were prepared for light microscopic examination. Sections were collected from the paraffin wax blocks and stained by H & E and finally examined by Olympus light microscope.
Results: Most of the seminiferous tubules from the formaldehyde exposed group were atrophied with no e

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Publication Date
Sat May 01 2021
Journal Name
Journal Of Physics: Conference Series
Effect of ginger alcoholic extract on the ovary tissue in quail

This research was carried out in quail in the laboratory of histopathology diseases during four months. The objectives of this study was to detecting the effects of the addition of the alcohol extract of ginger to ovary tissue of quail. The two groups of birds were in almost similar weights and were placed in cages. Each group consisted of 8 quails. The first group (control group) fed on regular feeding without adding alcoholic extract of ginger. The second group (treated group) fed on the same normal food after adding the alcohol extract of ginger at a concentration of 300 mg / kg. The results indicated that ginger have positive effects on folliculogenesis.

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Publication Date
Wed Apr 04 2012
Journal Name
The Iraqi Journal Of Veterinary Medicine
Toxicopathological study of aqueous extract of beetle cocoon Larinus maculatus F. on some internal organs in male albino mice

The present study was carried out to investigate the effect of oral administration of hot aqueous extract of beetle cocoon Larinus maculatus Faldermann, in a two doses 50 and100mg/Kg/Bw for 25 and 45days respect- tively on some organs such as liver, lung, kidney, intestine, heart, spleen, and brain in male mice Mus musculus. The results indicated that there were toxicopathological changes in many tissues of experimental animals. Histo -pathological changes was dose and period dependent . It was found that the aqueous extract of beetle cocoon has undesirable effect at the administered doses, since the raw extract of this cocoon is currently being used in Folk medicine as treatment for cough, bronchitis in Iraq. This study revealed that the l

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Publication Date
Thu Nov 30 2023
Journal Name
Iraqi Journal Of Science
The Effect of Sildenafil on Adenine-Induced Chronic Kidney Disease in Mice

     This study was done to find the potential renal protective effects of sildenafil and its underlying mechanisms in mice with adenine-induced CKD. For the experiment, 40 male mice were split into four groups. The control group (A) received the same food without medication until the research ends, while the other three collections (B, C, and D) were given adenine (0.25% w/w in feed daily for 8 weeks), groups (C and D) were given sildenafil (0.5 and 2.5 mg/kg) respectively orally every day for 30 days, and then blood samples were taken to assess the function of the kidneys (Urea, total protein, and creatinine), total antioxidant capacity (TAC), superoxide dismutase (SOD), and catalase (CAT) in addition to kidney histopathology, as w

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Publication Date
Mon Jun 19 2023
Journal Name
Journal Of Engineering
The Effect of Dynamic Loading on Stresses Induced in Charnley Hip Prosthesis

This study produces an image of theoretical and experimental case of high loading stumbling condition for hip prosthesis. Model had been studied namely Charnley. This model was modeled with finite element method by using ANSYS software, the effect of changing the design parameters (head diameter, neck length, neck ratio, stem length) on Charnley design, for stumbling case as impact load where the load reach to (8.7* body weight) for impact duration of 0.005sec.An experimental rig had been constructed to test the hip model, this rig consist of a wood box with a smooth sliding shaft where a load of 1 pound is dropped from three heights.
The strain produced by this impact is measured by using rosette strain gauge connected to Wheatstone

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Publication Date
Sun Sep 29 2019
Journal Name
Iraqi Journal Of Science
Effect of Cold Plasma on Histological Compositions of the Rabbits Fracture Bone Tissue

    In this research, the rabbits' bones have been fractured, the rabbits were exposed to the cold plasma for five minute times two weeks. The microwave plasma voltage which was used in the search was "175v" and the gas flow was" 2 L" at the room temperature.  A Biologic parameters such as alkaline phosphates (ALP), osteocalcin, vitamin D (Vit. D) and calcium (Ca), Triglycerides (TG), Cholesterol (T.chol.), Estradiol and Glucose have studied in its serum. Physiological parameters were measured to prove the effects of plasma on the fracture bone tissue and show the amount of damage and the effect of plasma therapy before and after exposure to plasma.

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Publication Date
Sun Sep 01 2019
Journal Name
Journal Of Physics: Conference Series
Seed weight effect on germination properties and seedling growth of some cultivars of lupine

A laboratory experiment was carried out and repeated at field of College of Agricultural Engineering Sciences, University of Baghdad in 2017. First factor was three cultivars of lupine 'Giza-1', 'Giza-2' and 'Hamburg'. Second factor was three seed weights (lower weight, medium weight and higher weight) which was following the cultivars factor. Nested design was used. Results showed supremacy of 'Giza-1' cultivar significantly and gave higher germination ratio, radical length, seedling dry weight, seedling vigour index, field emergence ratio, plant height and number of leaves per plant. The treatment ('Giza-1'×higher seed weight) was supremacy significantly and gave higher germination ratio, radical length, plumule length, and seedling vigo

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