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Given the increasing global use of antibiotics, it has become necessary to examine
and recognize their significance. An antibiotic formulation may contain one or more
active components, depending on the antibiotic’s type and formulation. Antibiotics
act exclusively against bacterial diseases and are ineffective against viral infections
such as the common cold and influenza. The purpose of this review is to analyze the
existing literature on the determination of antibiotics and to present the methods used for
estimating specific antibiotics, including cephalexin, cloxacillin, piperacillin, nafcillin,
and cefamandole, in medicinal preparations and biological fluids, such as blood and
urine, from humans and animals. Verifying the quality of
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