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The role of Tumour Necrosis Factor Alpha (TNF-ALPHA) serum level and genetic polymorphisms with cutaneous leishmania infections
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Objective: To assess the role of tumour necrosis factor alpha level and genotyping in susceptibility to leishmaniasis.Method: The case-control study was conducted from March to July 2021 at Baqubah Teaching Hospital, Diyala, Iraq,and comprised patients of cutaneous leishmaniasis in group A and healthy controls in group B. The serum level andsingle nucleotide polymorphisms of tumour necrosis factor-alpha rs41297589 and rs1800629 were compared betweenthe groups. Data was analysed using SPSS 28.Results: Of the 150 subjects, there were 75(50%) in group A; 39(52%) males and 36(48%) females with mean age23.91±13.14 years. The remaining 75(50%) subjects were in group B; 38(50.7%) males and 37(49.3%) females withmean age 22.84±4.35 years. Tumour necrosis factor-alpha level in group A was 55.81±39.64 compared to 7.51±3.61in group B (p<0.05). Single nucleotide polymorphism rs41297589 showed that TT genotype and T allele weresignificantly increased in group A compared to group B (p<0.05), while rs1800629 showed that GA genotype and Aallele were significantly increased in group A compared to group B (p<0.05). The serum level of tumour necrosis factoralphain group A was increased in TT genotype compared to other genotypes at rs41297589, and in GA genotypecompared to other genotypes at rs1800629 (p<0.05).Conclusions: There was a significant association between tumour necrosis factor-alpha serum level and geneticpolymorphisms rs41297589 and rs1800629 among cutaneous leishmaniasis patients.Keywords: Polymorphism, Nucleotide, Alleles, Psychodidae, Leishmania, Parasites, Cutaneous, Nucleotides.

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Publication Date
Thu Jul 01 2021
Journal Name
Journal Of Physics: Conference Series
Compatibility and Edge Spaces in Alpha - Topological Spaces
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Abstract<p>This research presents the concepts of compatibility and edge spaces in <italic>α</italic>-topological spaces, and introduces the <italic>α</italic>-topology combinatorially induced by the <italic>α</italic>-topology. Furthermore, studies the relationship between the <italic>α</italic>-topology on <italic>V</italic> ∪ <italic>E</italic> and the relative <italic>α</italic>-topology on <italic>V</italic>.</p>
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Publication Date
Thu Sep 30 2021
Journal Name
Iraqi Journal Of Science
CutPoints and Separations in Alpha- Connected Topological Spaces
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     This paper introduces cutpoints and separations in -connected topological spaces, which are constructed by using the union of vertices set and edges set for a connected graph, and studies the relationships between them. Furthermore, it generalizes some new concepts.

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Publication Date
Tue Sep 01 2020
Journal Name
Asian Journal Of Pharmacy And Pharmacology
Genetic polymorphisms associated with diabetic foot ulcer: A review article
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Publication Date
Tue Sep 01 2020
Journal Name
Asian Journal Of Pharmacy And Pharmacology
Genetic polymorphisms associated with diabetic foot ulcer: A review article
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Diabetic foot ulcer (DFU) or Lower limb ulcers are one of the major complications caused by diabetes mellitus especially when patients fail to maintain tight glycemic control. DFU is linked to multiple risk factors along with the genetic factors and ethnicity which play a significant role in the development of DFUs through their effects on multiple aspects of the pathophysiological process. This narrative review aimed to summarize all the previous studies within the last ten years associating gene polymorphism and DFU. Polymorphism associated with vascular endothelial growth factor (rs699947), the G894T polymorphism of the endothelial nitric oxide synthase gene, interleukin-6–174 G>C gene polymorphism, heat shock protein 70 gene polymorph

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Publication Date
Wed Mar 18 2020
Journal Name
Baghdad Science Journal
Incidence of Toxoplasmosis in Psoriasis Patients and Possible Correlation with Tumor Necrosis Factor-α
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            Toxoplasma gondii is an opportunistic parasite in immune-compromised persons. The prevalence of toxoplasmosis in psoriasis patients is investigated. In addition, the treatment effect on psoriasis patients infected with toxoplasmosis through evaluating Tumor Necrosis Factor-α (TNF-α) cytokine levels is studied. Blood samples were collected from 130 individuals who involved 60 control samples and 70 samples with psoriasis. They attended Medical City Hospital in Baghdad province from October 2017 - February 2018. Then, the anti- T. gondii antibodies (IgM and IgG) and TNF- α in the sera were determined via the enzyme linked immune-sorbent assay. The highe

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Publication Date
Mon Nov 01 2021
Journal Name
University Of Baghdad, College Of Education For Pure Sciences \ Ibn Al-haitham, Department Of Mathematics
SOME ALPHA-TOPOLOGICAL CONCEPTS USING GRAPH THEORY
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This dissertation depends on study of the topological structure in graph theory as well as introduce some concerning concepts, and generalization them into new topological spaces constructed using elements of graph. Thus, it is required presenting some theorems, propositions, and corollaries that are available in resources and proof which are not available. Moreover, studying some relationships between many concepts and examining their equivalence property like locally connectedness, convexity, intervals, and compactness. In addition, introducing the concepts of weaker separation axioms in α-topological spaces than the standard once like, α-feebly Hausdorff, α-feebly regular, and α-feebly normal and studying their properties. Furthermor

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Publication Date
Sat Jun 30 2007
Journal Name
Iraqi Journal Of Chemical And Petroleum Engineering
Alpha-Alumina Extraction from Al-Ga'ara Bauxite
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The bauxite produced from Al-Ga 'ara area in Al-Enbar containing 50.4 wt. percentages Al2O3 was used for a- alumina production.                                                                                                

For α-alumina pro

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Publication Date
Fri Jan 01 2021
Journal Name
Aip Conference Proceedings
Study of rheological and mechanical properties of bitumen blended with two alpha phases of polyamide
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Publication Date
Fri Jan 01 2021
Journal Name
Aip Conference Proceedings
Study of rheological and mechanical properties of bitumen blended with two alpha phases of polyamide
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The effect of D phase polyamide (PA6)on the rheological properties, Young Modulus and the thermal expansion coefficient of two blends groups (bitumen-polyamide) were tested. The first group was for bitumen-PA6 blends and the second group for bitumen blended with polymer resulted from the crystallization of PA6-formic acid solution in water(PAFW).The obtained results proved that adding both types of polyamide has led to a rise in toughness and softening point temperature while the penetration Index approached -3 after adding the polyamide. So, all these changes make bitumen-polyamide blends more suitable for use in hot climate regions. The blends properties were explained according to the reaction that takes place between the polyamide and

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Publication Date
Thu Jan 02 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Effect of alpha-1antitrypsin,adiponectine,leptein in obesity
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Background:- Obesity is associated to significant disturbances in endocrine function. Hyper insulinemia and insulin resistance are the best known changes in obesity, but their mechanisms and clinical significance are not clearly established.

Objectives:- to investigate the relationship between alph-1 antitrypsin,leptein,adiponectein in  serum of an obese population to find new markers for treating obesity and related disease.

Patients and methods:-This study had included thirty patients with obese (12 male and 18 female) with age ranged between 30-45 years and thirty apparently subjects matched for age and weight have been studied, attending the out patients consulta

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