Preferred Language
Articles
/
0uYGrZwBmraWrQ4dZE3t
Evaluation of SOD and MDA levels with the Cytotoxicity of some Plant Extracts Toward Human Rhabdomyosarcoma Cell Lines
...Show More Authors

حظيت السمية الخلوية للمستخلصات النباتية باهتمام كبير في السنوات الأخيرة لتقييم نشاطها ضد الأورام. تركز الوقاية الكيميائية من السرطان على السمية الخلوية للمستخلصات النباتية لتكون سامة تجاه خطوط الخلايا السرطانية دون أن تؤثر على الخلايا الطبيعية. الهدف من هذه الدراسة هو تقييم السمية الخلوية لمستخلصي الزنجبيل و أوراق الزيتون ومزيجهما بنسبة 1: 1 تجاه خطوط خلايا RD وتقدير فعالية هذه المسخلصات ضد الاجهاد التاكسدي  بدلالة SOD و MDA. تم الحصول على المستخلصات الكحولية لكل من الزنجبيل وأوراق الزيتون بطريقة السوكسيلت. وحضر المستخلص الثالث بخلط كميات متساوية من مستخلص أوراق الزيتون والزنجبيل بنسبة 1: 1. تم تحضير اطباق من خطوط الخلايا RD وخطوط الخلايا الاعتيادية وتم اختبار تراكيز مختلفة من المستخلصات المحضرة (12.5 - 800 ميكروغرام / مل) لتسجيل فعالياتهم تجاه كل من RD وخطوط الخلايا الطبيعية. . كذلك ، تم تقدير  مستوى انزيم  SOD و MDA اعتمادًا على طرائق العمل الخاصة بهما. اظهرت النتائج  وجود فرق معنوي بين السمية الخلوية للتراكيز المدروسة لكل مستخلص تجاه خطوط الخلايا RD، اذ انخفضت قابلية بقاء خطوط الخلايا RD مع زيادة تراكيز المستخلصات ، وفي نفس الوقت لم تؤثر تلك  المستخلصات على خطوط الخلايا الطبيعية. كذلك بينت النتائج ازدياد مستويات SOD مع زيادة تركيز المستخلص على عكس مستويات MDA التي انخفضت مع زيادة تراكيز المستخلص. يمكن الاستنتاج بان نشاط المستخلصات المحضرة تجاه خطوط الخلايا RD دون التأثير على خطوط الخلايا الطبيعية يعزز مبادئ المنع الكيميائي للسرطان ، إلى جانب الخصائص المضادة للأكسدة التي يمكن أن تقلل من الإجهاد التأكسدي الذي يصاحب الخلايا السرطانية  وتنشيط العوامل الطبيعية المضادة للاكسدة في جسم الانسان.   

Scopus Crossref
View Publication
Publication Date
Fri Jan 01 2021
Journal Name
Materials Today: Proceedings
Influence of design anode and cathode channel on (PEMFC) fuel cell performance
...Show More Authors

View Publication
Scopus (17)
Crossref (13)
Scopus Clarivate Crossref
Publication Date
Thu Aug 01 2024
Journal Name
Journal Of Engineering Research
Design, analysis and development of a proton exchange membrane in fuel cell
...Show More Authors

View Publication
Scopus (5)
Crossref (3)
Scopus Clarivate Crossref
Publication Date
Wed Sep 20 2023
Journal Name
Ankara Universitesi Eczacilik Fakultesi Dergisi
ANTIANGIOGENIC ACTIVITY AND ROS-MEDIATED LUNG CANCER CELL LINE INJURY OF ZERUMBONE
...Show More Authors

Objective: Zerumbone (ZER) is a well-known natural compound that has been reported to have anti-cancer effect. Thus, this study investigated the ZER potential to inhibit Thymidine Phosphorylase (TP) and the ability to trigger Reactive oxygen species (ROS)-mediated cytotoxicity in non-small cell lung cancer, NCI-H460, cell line. Material and Method: The antiangiogenic activity for ZER was evaluated by using the thymidine phosphorylase inhibitory test. Reactive oxygen species (ROS) production was determined via DCFDA dye by using flow cytometry. Result and Discussion: ZER was found to be potent TP inhibitory with the IC50 value of 50.3± 0.31 μg/ml or 230±1.42 µM. NCI-H460 cells upon treatment with ZER produced sign

... Show More
View Publication
Scopus (5)
Crossref (2)
Scopus Crossref
Publication Date
Tue Jul 04 2023
Journal Name
Ankara Universitesi Eczacilik Fakultesi Dergisi
ANTIANGIOGENIC ACTIVITY AND ROS-MEDIATED LUNG CANCER CELL LINE INJURY OF ZERUMBONE
...Show More Authors

Objective: Zerumbone (ZER) is a well-known natural compound that has been reported to have anti-cancer effect. Thus, this study investigated the ZER potential to inhibit Thymidine Phosphorylase (TP) and the ability to trigger Reactive oxygen species (ROS)-mediated cytotoxicity in non-small cell lung cancer, NCI-H460, cell line. Material and Method: The antiangiogenic activity for ZER was evaluated by using the thymidine phosphorylase inhibitory test. Reactive oxygen species (ROS) production was determined via DCFDA dye by using flow cytometry. Result and Discussion: ZER was found to be potent TP inhibitory with the IC50 value of 50.3± 0.31 μg/ml or 230±1.42 µM. NCI-H460 cells upon treatment with ZER produced sign

... Show More
Scopus (5)
Crossref (2)
Scopus Crossref
Publication Date
Sun Jun 01 2014
Journal Name
Baghdad Science Journal
Evaluation of the Organic-Pollution Based on the Determination of some Polycyclic Aromatic Hydrocarbons(PAHs) in Tigris River Water in 2012 at Baghdad City , Iraq
...Show More Authors

This study aims to predict the organic pollution produced from the presence of some polycyclic aromatic hydrocarbons (PAHs) and determination it's concentrations (µg/L , ppb) in Tigris river water by a collection twenty-seven water samples from a selected three stations with nine sampling sites and three depths of water (5 cm , 2 m and 4 m) each site for 4.6 km distance of a geographic studied area which is located between the ( Al-Senak and AL-Sarrafiah bridges ) at Baghdad city – Iraq on May, 2012. The geographic location was determined with a Global Positioning System (GPS) and Geographic Information System (GIS) software program. The concentrations of fourteen components (PAHs) were performed using the reverse phase

... Show More
View Publication Preview PDF
Crossref (1)
Crossref
Publication Date
Sun Jan 01 2023
Journal Name
International Journal Of Work Innovation
Reducing the negative effects of non-compliance and unethical behaviour by adopting the risk approach to human resources management
...Show More Authors

View Publication
Scopus (6)
Scopus Crossref
Publication Date
Tue Jan 01 2019
Journal Name
Journal Of Global Pharma Technology
Serum levels of cross-linked n-telopeptide of Type i collagen before and after non-surgical periodontal therapy in type 2 diabetic patients with chronic periodontitis
...Show More Authors

Background: Diabetes mellitus is a major risk factor for chronic periodontitis (CP) and hyperglycemia has an important role in the enhancement of the severity of the periodontitis. It has been reported that the progression of CP causes shifting of the balance between bone formation and resorption toward osteoclastic resorption, and this will lead to the release of collagenous bone breakdown products into the local tissues and the systemic circulation. Cross-linked N-telopeptide of type I collagen (NTx) is the amino-terminal peptides of type I collagen which is released during the process of bone resorption. This study was conducted to determine the effects of nonsurgical periodontal therapy on serum level of NTx in type 2 diabetic patients

... Show More
Publication Date
Wed Jun 17 2026
Journal Name
Journal Of Baghdad College Of Dentistry
Evaluation of the effectiveness of coenzyme Q10 gel in management of patients with chronic periodontitis (I intra group comparison)
...Show More Authors

Background: Periodontal pathogens can induce free radicals over-formation and thus may cause collagen and periodontal destruction. Anti-oxidants are used as supplements to counteract the over production of free radicals in periodontal disease, that can reduce of collagen destruction. Coenzyme Q10 serves as an endogenous antioxidant, regenerates other antioxidants, stimulates cell growth, and inhibits cell death. Because it is an antioxidant, coenzyme Q10 has received much research attention associated with periodontal diseases. Perio Q gel may possibly be effective as a topical agent and as an adjunct to scaling& root planing in treatment of gingivitis and chronic periodontitis. Aim of study:Determine the periodontal health status in a foll

... Show More
View Publication Preview PDF
Publication Date
Thu Sep 05 2019
Journal Name
Journal Of Engineering / University Of Baghdad
Subsurface Water Retention a Technology for Increasing the Field Use Efficiency and Water Saving Values of Cucumber Plant
...Show More Authors

The technology of subsurface soil water retention (SWRT) uses a polyethylene trough that is fixed under the root zone of the plant. It is a modern technology to increase the values of water use efficiency, plant productivity and saving irrigation water by applying as little irrigation water as possible. This study work aims at improving the crop yield and water use efficiency of a cucumber plant with less applied irrigation water by installing membrane trough below the soil surface. The field experiment was conducted in the Hawr Rajab District of Baghdad Governorate in Winter 2018 for testing various trickle irrigation systems. Two agricultural treatment plots were utilized in a greenhouse for the comparison. Plot T1 has used a subsurface t

... Show More
View Publication
Crossref (1)
Crossref
Publication Date
Wed Aug 28 2019
Journal Name
Journal Of Engineering
Subsurface Water Retention a Technology for Increasing the Field Use Efficiency and Water Saving Values of Cucumber Plant
...Show More Authors

The technology of subsurface soil water retention (SWRT) uses a polyethylene ‎trough that is fixed under the root zone of the plant. It is a modern technology to increase the values of water ‎use efficiency, plant productivity and saving irrigation water by applying as little irrigation water ‎as possible. This study work aims at improving the crop yield and water use efficiency of a cucumber plant with less applied irrigation water by installing membrane trough below the soil surface. The field experiment was conducted in the Hawr Rajab District of ‎Baghdad Governorate in Winter 2018 for testing various trickle irrigation ‎systems. Two agricultural ‎treatment plots were utilized in a greenhouse for the compa

... Show More
View Publication Preview PDF
Crossref (1)
Crossref