Background: Simvastatin (SIM) is a lipid-lowering agent to prevent disorders caused by clogged blood vessels. Because of its low solubility, it has low bioavailability. The adsorption technique is effective in improving drug solubility and dissolution rate. Objective: To use magnesium aluminum silicate (MAS) as an adsorbent in combination with Soluplus® as a hydrophilic polymer to formulate SIM as immediate-release tablets (IRTs). Methods: We used the solvent evaporation method to make MAS-loaded SIM in the presence of Soluplus®, making sure that the ratio of SIM to MAS to SOLU was 1:6:3. We then used this mixture to make IRTs. Using the direct compression method, we made all of the SIM-IRT formulas. We used diluents like Avicel

       This study introduces a series of single and pile group model tests subjected to lateral loads in . multilayered sand from Karbala, Iraq. The aim of this study is to investigate: the performance of the pile groups subjected to lateral loads; in which the pile batter inclination angle is changed; the effect of pile spacing (s/d) ratio, the influence of using different number of piles and pile group configuration. Results revealed that the performance of single negative (Reverse) Battered piles with inclination of 10° and 20° show a gain of 32% and 76 % in the ultimate lateral capacity over the regular ones. For pile groups, the use of a combination of regular, negative and positive battered piles in

The spectrum known represented as a relationship that’s plotted between the magnitudes or energy for a specific parameter vs. its frequency, the wind spectrum is presented as the sum of wind speed created by events divided either in space, in time, or both. This paper presents a wind speed spectrum demonstration in
Ali Al-Gharbi location in Iraq. The aim of the present paper is to analysis the wind speed and direction by employing the FFT (Fast Fourier Transform) therefore field measurement of wind speed and direction were collected for one year from Dec 2014 to Dec 2015 in the time interval of 10 minutes at heights of 10, 30 and 50
meters. From the performance of the FFT it was found that the v

This research explores the preparation of polypyrrole (PPy) using chemical oxidation and its enhancement with graphene oxide (GO) for optical sensor applications. PPy was synthesized by polymerizing pyrrole monomers with ferric chloride (Fe2Cl3) as the oxidant. The resulting PPy was then combined with GO to form a composite material, aiming to improve its electrical and optical properties. Polypyrrole nanofibers were obtained and after adding graphene oxide, the sensitivity increased. Characterization techniques including UV-Vis spectroscopy, DC conductivity measurements, Field Emission Scanning Electron Microscopy (FESEM) and response of photocurrent analysis were employed. The incorporation of GO into PPy resulted in a significant reducti

Darifenacin hydrobromide is a selective ?₃ receptor antimuscarinic drug and it is used in the management of urinary frequency, urgency, and incontinence in detrusor instability. It slightly soluble in water, undergoes extensive hepatic first-pass metabolism and has short elimination half-life (3–4 hours). Therefore, It has low bioavailability (15.4 % - 18.6 %). Darifenacin hydrobromide loaded NLCs were formulated by emulsification sonication using different ratios of solid lipid to liquid lipid, different types of surfactants, and different concentration of surfactants. Formula sixteen was considered as an optimized formula based on its particle size, PDI, zeta potential and entrapment efficiency. Formula sixteen subjected t

What is meant by objectives: the purpose, secrets, judgment, and interests that the legislator set for each of its rulings is a doctrine and a law.

Faith is belief with certainty in God Almighty, and what is required of him in his divinity, lordship, names and attributes, belief in his angels, books, messengers, the Last Day and destiny, both good and bad.

And the purposes of faith are the wisdom and secrets contained in the Islamic faith and which achieve human well-being and happiness in the immediate and the future. And that the purposes of belief and faith are the essence of religion, rather it constitutes a basic pillar on which the basis of the intentional consideration as a whole, because the structure of worship i

     The aims of visible watermarking are to prevent the illegal copying of videos and images and to avoid the theft and unauthorized advertisement of the legitimate owners' content. The visible watermark is distinguishable with the naked eye. This makes it easily removed by an attacker. This paper proposes an anti-removable visible logo by double embedding using the discrete wavelet transform (DWT) and a chaotic map. The main purpose of this method is to prevent the removal attack and restore the original video without information loss after the logo is legally removed. DWT is used for both the cover area and the logo to embed sub-bands of information from the cover area into sub-bands of the logo. The main idea of using a chaotic m

In this work, polyvinylpyrrolidone (PVP), multi-walled carbon nanotubes (MWCNTs) nanocomposite was prepared and hybridized with Graphene (Gr) by the solution casting method.  The morphological and electrical properties were investigated by field effect scanning electron microscopy (FESEM) images, portraying a uniform dispersion of graphene within the PVP-MWCNT nanocomposite. The AC conductivity increased from (1.45552) to (2.34812) (Ω cm)^-1 with the use of nanocomposite. The increasing continues for the AC conductivity after hybridized with graphene up to (7.20641) (Ω cm)^-1. In addition, the performances of the prepared samples for gas sensor application have been investigated.

This study was carried out to evaluate parasitological and immunological of the effect of chitosan and chitosannanoparticles loaded with spiramycin on toxoplasmosis infected mice. After injection intra peritoneal with 103viable tachyzoites for acute infection, treatments given for seven days. Peritoneal fluid examination revealed a significant decrease in the number of Toxoplasmagondiitachyzoites in all treated infected mice compared with infected non-treated. The combined therapy gave better results than single. The best effect was observed in group of mice treated with spiramycin combined with chitosan nanoparticles. Also immunoglobulin Ig Manti body and gamma Interferon (INFγ), Tumor Necrosis Factor alpha (TNF-α) cytokines responses ag