Professor Husam Salman Jasim, a graduate of the University of Baghdad, College of Education for Pure Sciences, Ibn Al-Haitham, Department of Chemistry, holds a master’s degree from the above college, specializing in biochemistry, and is now in the research phase to complete his doctoral studies.
Conducting clinical research on diseases affecting the body and holding seminars and workshops related to the field of chemistry
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Member of the Chemists Syndicate Member of the International Ared Platform
Conducting research in the fields of biochemistry and organic chemistry
biochemistry and organic chemistry
Organic Chemistry Lab / Second Stage Biochemistry Lab / Fourth Stage Organic Diagnostic Lab / Fourth Stage Specialized Theory (Food Chemistry) / Third Stage General Chemistry Lab for Biomedical Students / Second Stage
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Many previous investigations have found quercetin to be a powerful antioxidant and antitumor flavonoid, but its poor bioavailability has limited its use. This current study investigated the effects of two newly synthesized Quercetin Schiff bases containing 2-amino thiadiazole-5-thiol (Q1), and its benzyl derivatives (Q2) on MCF-7 human breast cancer cells. Cell viability and apoptosis were assessed to determine the toxic effects of Q1 and Q2. Cytotoxicity valuation showed that both compounds inhibited MCF-7 cell growth, and lactate dehydrogenase (LDH) activity increased in a dose-dependent aspect compared to the control group. Comet assay results observed that Q1 and Q2 induce more serious DNA damage than the control (untreated cell
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