وصف حالة لسرطان غدة الكظر( ACC) العاملة الغير المتفاقمة في صبي عمره 8 سنوات الذي قدم لنا تاريخ من سن البلوغ المبكر لوحظ من قبل والديه منذ ثلاثة أشهر.

وأظهرت الموجات فوق الصوتية للبطن كتلة كبيرة واضحة المعالم فوق الكلية اليمنى (منطقة الغدة الكظرية) مع تكلس وتنخر, وأظهرت نتائج الرنين المغناطيسي  ((MRI  هذه الكتلة أن تكون قليلة الكثافة ( hypojntense) إلى الكبد في T1 وفرط في الكثافة (hyperinte

مقدمة:الكسر الخلعي عند المفصل بين الفقرات الصدريه مع الفقرات القطنية الناتج عن شدة خارجية ذات طاقة شديدة مباشرة أو غير مباشرة  عادة يتم علاجها بتثبيت يصل الى ثلاث فقرات. تثبيت الفقرات باستعمال جزء صغير من العمود الفقري لديه فوائد عديدة منها قصر وقت العملية اضافة لتقليل العوامل النفسية والوظيفية التي تسبب عوق مابعد العملية مع المضاعفات في موقع العمليه في الجسم نفسه.

الهدف من ألبحث ت

خلفية الموضوع: العلاقة بين التغير الوراثي رقم 308 لعامل تنخر الخلايا السرطانية نوع الفا ومرض السكري النوع الثاني يبقى مصدر جدل واختلاف في الاصول وانماط الحياة التي تلعب دور مهم في هذا التضارب.

الهدف :لبحث دور التغير الوراثي رقم 308 في عامل تنخر الخلايا السرطانية نوع الفا مع مرض السكري النوع الثاني ومعيار كتلة الجسم في هؤلاء المرضى.

طرائق العمل: الدراسة الحالية تضمنت خمسون مر

خلفية البحث:  إن جراحة تثبيت العمود الفقري باستخدام مسمار قدم الفقرات أصبحت من الوسائل الشائعة في جراحه العمود الفقري. رغم التطور الذي في تقنيات و تصاميم وسائل هذه ألجراحه و استخدام التصوير ألشعاعي إثناء هذه ألجراحه لازالت هنالك احتماليه وضع هذا المسمار في غير موضعه الصحيح محدثا ثقوبا في قشره قدم الفقرات مهددا أصابه الأحشاء العصبية و الوعائية ما حول الفقرات.

ال

Background: A comparism study for management of deep seated small brain tumors less than 4 cm in the 3 diameters between cases managed by Brain lab navigator and those without it.
Patients and methods: We took 20 patients from the retrospecture data before the use of Navigator in our country compared with the 20 patients managed after the use of navigator in our hospital (specialized surgical hospital) in the neuro-surgical. Unit since 2002 till now. From 1/8/2002 till 31/12/2007 the study included the type of tumor & surgery & the result of surgery & time & complications ((morbidity & mortality)).
Results: There was a significant increase of the safety of surgery by using the navigator

Background: Preeclampsia, the de novo occurrence of hypertension and proteinuria after the 20th week of gestation, continues to exert an inordinate toll on mothers and children alike.
The idea that asymmetric dimethylarginine (ADMA) accumulation may be a cardiovascular risk factor in patients with preeclampsia was advanced in 2003. Furthermore, High ADMA levels have been associated with alterations in the regulation of cerebral blood flow and neural function, with insulin resistance, thyroid dysfunction, and alterations in bone homeostasis, fertility, and erectile function.
Subject and methods: the present study is a cross-sectional case-control study includes measurement of s.ADMA in 60 patients with

Background: This study is concerned with the effects of preeclampsia on the availability of the important enzymes in the full term placenta.For this purpose 2 groups of placentae were taken from the full term pregnant women immediately after labour, each group consists of 10 placentae, the first group are those placentae obtained from pregnant women having uneventful pregnancy with no history of any disease or complication (as a control group) while the second group includes those pregnant women having a history of preeclampsia, the results showed significant histochemical changes in the placentae of the second group when compared with the first group, such changes result from syncytial damage and destr

Background: Polycystic ovarian syndrome (PCOS) is one of the most common cause of anovulation during reproductive life.Resistin can increase ovarian androgen production by directly stimulating ovarian theca cell or indirectly by augmenting pancreatic – B cell production of insulin.
Patients and Methods: Sixty patients with PCOS who were non diabetic and not taking any medicine for the last three months were involved in the study .Thirty normal fertile female serves as control group. Fasting blood samples were aspirated from all individuals from 3rd - 6th day of the menstrual cycle to measure resistin, insulin, glucose, LH, FSH, TT3, TT4, Prolactin , Total Testosterone and lipid profile, by ELISA and rou

Background: Cholecystectomy in cirrhotic patients is commonly followed by high morbidity and mortality, the incidence of hepatic cirrhosis has increased since last decade as well as the occurrence of complication such as liver failure, portal hypertension, and biliary disorders.
Patients and methods: laparoscopic Cholecystectomy was performed in 24 cirrhotic patients (18 child A and 6 child B) in an effort to obtain lower complications and mortality rates. The mean age of the group was 51.8 years, ten of the 24 patients were men and 14 female.
Results: intraoperative complications such as bleeding, dense adhesion and long operative time were recorded.
Conclusion: laparoscopic Cholecystectomy was safe and

Background: Hydrocephalus is an imbalance of cerebro-spinal fluid (CSF) formation & absorption of sufficient magnitude to produce a net accumulation of fluid within to cerebral ventricles.
Aim of study: the main objective of this study is to compare frontal with post parietal shunt regarding the surgery complications , end results & then to compare it with other studies abroad.
Patient & Methods: this study included 920 patients admitted to the Neurosurgical department in the Hospital of surgical specialty,Medical city. The patients had full radiological study including MRI and CT . All patients were surgically managed & followed up for at least one year.
Results: results were & compared regarding the type of

Background: Alcohol remains the single most significant Cause of liver disease throughout the Western World, responsible for between 40 and 80% of cases of cirrhosis in different countries. Many of the factors underlying the development of alcoholic liver injwy remain unknown, and significant questions remain about the value of even very basic therapeutic strategies.
Patients and Methods: A total number of 113 patients with ALD attending the Gastroenterology and Hepatology teaching hospital between December 2001 and December 2003 were studied for the gastrointestinal, esophagogastroduodenoscopic manifestation of alcoholic liver disease.
Results.'The most common presenting symptom was jaundice (62.8%), anorexia, weight loss (39.8-54

Background: Venous leg ulcers (VLUs) affect 1-3% of the population and impose substantial pain-related morbidity, yet vascular pain remains underrecognized in clinical practice and research.

Objectives: This narrative review synthesizes current evidence on the pathophysiology, clinical manifestations, and management strategies for VLU-associated pain.

Methods: A comprehensive literature search was conducted across PubMed/MEDLINE, Scopus, Embase, and Web of Science (January 2015-July 2025) following SANRA guidelines. Search terms included "vascular pain", "venous leg ulcer", "chronic venous disease" and related terminology. Studies addressing pathophysiology, clinical charac

Background: Gallstone disease is a major global health problem, the prevalence of which depends on metabolic, genetic, and infectious factors. Recent reports point out that Gram-positive bacteria, mainly Staphylococcus aureus and Enterococcus species, are also involved in the development of gallstones via enzyme action and biofilm formation.

Objectives: To characterize Gram-positive bacteria within gallstones from Iraqi patients, evaluate their biofilm-forming capacity, and analyze the relationship between bacterial colonization, gallstone type, as well as cholesterol levels.

Methods: A total of 100 gallstones were obtained from 100 patients undergoing

Background: Burn injuries disrupt skin barriers and weaken immune defenses, predisposing patients to opportunistic, drug-resistant Gram-negative infections. These findings highlight the urgent need for targeted prevention and treatment strategies in burn care settings.
Objective: To evaluate the prevalence, pattern as well as clinical significance of Pseudomonas aeruginosa and Acinetobacter baumannii in patients with burns.
Method: A prospective observational study was conducted from April 2024 to April 2025. One hundred and fifty clinical samples from burn patients were collected and processed using standard microbiological methods. Identification of

Background: Diabetic nephropathy (DN) is a significant contributor to end-stage renal failure in individuals with type 2 diabetes mellitus (T2DM). Diabetic nephropathy is characterized by tubular atrophy, glomerular dilation, glomerulosclerosis, interstitial fibrosis, and proteinuria, resulting in deterioration of kidney function. DN, primarily caused by hyperglycemia, accounts for millions of deaths globally and is the leading cause of end-stage renal disease. Matrix metalloproteinase 10 is an enzyme essential for the breakdown of extracellular matrix constituents. Fetuin-A forms soluble complexes with calcium and phosphate to prevent soft tissue mineralization

Objectives: To determine the levels

Background: Multiple sclerosis (MS) is an autoimmune illness that can be triggered by both hereditary and environmental factors. There are crucial roles for the neuroendocrine system in initiating autoreactive immunity at this stage. Copeptin is a promising inflammatory marker that has the potential to be employed as a prognostic factor in several disorders, particularly those affecting the central nervous system. Objectives: In this research we attempt to evaluate the relation of serum copeptin concentrations with weight increment in Iraqi patients with multiple sclerosis. Methods: A cohort of Sixty Iraqi patients with multiple sclerosis took part in this study and classified equally into three groups; obese group, overweight group, and

Background: Acne vulgaris (AV) is a skin disorder affecting both sexes, starting at adolescence, and might continue into late adulthood. It is represented by a flare-up of nodular and postural lesions. Acne vulgaris patients with severe presentation suffer the consequences of skin scarring and disfigurement. Both Interleukin 1 beta (IL-1β) and Interleukin 8 (IL-8) are pro-inflammatory cytokines that play a significant role in acne pathogenesis and disease progression.  
Objectives: To assess the serum level of interleukin 1 beta and interleukin 8 in acne patients and see how it correlates with the severity of the disease.
Methods: It was a case–control study conducted from

Background: Multiple myeloma (MM) is characterized by clonal proliferation of malignant plasma cells within the bone marrow. In most patients, monoclonal immunoglobulin heavy chains or light chains are produced and are associated with organ dysfunction. The growth factor B-cell activating factor (BAFF) plays an important role in the pathogenesis of multiple myeloma due to its ability to promote B-cell survival, expansion, and differentiation.

Objective:  to measure the circulatory level of B-cell activating factor in multiple myeloma patients in relapsed and remission states and explore its possible correlations with the clinical staging, β2-microglobulin, and interleukin-6.

Metho

Background: Prostate cancer (PCa) is the most prevalent non-cutaneous malignancy and the second-leading cause of cancer-relatedmortality among males. Cancer is just one of the several disorders that may be linked to variations in trace element concentrations.
Objective: To evaluate serum arrestin β-2 as a prostate cancer tumor marker and its association with trace elements.
Methods: This case- control study was carried out at the Department of Biochemistry, College of Medicine, University of Baghdad and at the Urology department, Ghazi Al-Hariri Hospital for Surgical Specialities during the period from March 2022 to May 2023. In this case-control study 120 males were enrolled:

Background: Many characteristics between benign and malignant prostatic tumor which considered similar that make the diagnosis defaults in spacemen of the tumor. The immunohistochemical procedure can improves conventional tumor morphology by identifying lineage- and tumor-associated proteins or markers, facilitating confirmation of prostate origin and distinguish between benign and malignancy tumors.
Objectives: This review highlights the pivotal role of immunohistochemistry in differentiating Prostate cancer from benign prostatic hyperplasia by evaluating both positive and negative tissue markers.
Methods: A narrative review was conducted using methodological features to evalu

both strongly associated with vascular and metabolic complications. Endothelin-1 is a potent vasoconstrictor that plays a key role in vascular tone regulation and endothelial function.

Objective: To evaluate serum Endothelin-1 levels, lipid profile parameters (total cholesterol, LDL-C, VLDL-C, HDL-C, triglycerides), and HbA1c in patients with type 2 diabetes and essential hypertension compared with healthy controls, in order to assess their association with vascular injury and metabolic risk.

Methods: A case-control study was conducted in the Department of Biochemistry, College of Medicine, University of Baghdad. Between November 2024 and February 2025, a sample of patients were recruited f