Background: Urany1 acetate (UA) mostly a kidney poison or chemical toxic and not nearly so much radiological also is not accumulative toxic, so it is not concentrated in the food chain nor would it cause pathological condition due to increase levels from expomers. Therefore, the study aimed to detect the target organ as most of the lethal dose (LD50) male rats died within 24 hours.
Methods: Study was done on (120) male rats of 2 months old, at varying dosage level of uranyl acetate ranging from LD 50 of 2.5 and 1.5gm/kg and varying dosage level, by oral intubation. There were (40) rats for LD 50 were given single oral dose from 2.5 to 1.5 gm /kg every day. Eighty rats for the main study, (20) rats each gr
Background: Polycythemia (or polycythaemia or erythrocytosis) is a condition in which there is a net increase in the total number of blood cells, primarily red blood cells, in the body. The overproduction of red blood cells may be due to a primary process in the bone marrow (a so-called myeloproliferative syndrome), or it may be a reaction to chronically low oxygen levels or, rarely, a malignancy. Minerals are the building blocks of our bodies. They are required for body structure, fluid balance, protein structures and to produce hormones. They are the key for the health of every body system and function. They act as co-factors, catalysts or inhibitors of all enzymes in the body .
Patients and Methods: B
خلفية الموضوع: المالاسيزيا خميرة أحادية القطب تتعايش على الجلد وقد تكون ممرضة تحت بعض الظروف البيئية. خميرة المالاسيزيا معروفة كنبيت طبيعي للفقريات ذوات الدم الدافئ. الصدفية هو مرض جلدي غير معروف المسبب، يُعتقد بأن الفطريات قد تثير الأمراضية.
الأهداف: على الرغم من أن دور المالاسيزيا ما زال غير مفهومة تماما في أمرضية الصدفية ، ويعتقد أن هذه الخمائر محبة للدهو
... Show Moreالخلاصة
المقدمة: يعتبر تساقط الشعر حالة جلدية شائعة جدًا عادة ما يكون مصحوبا بأثار نفسية كبيره على المرضى,تساقط الشعر الكربي من الاسباب الأكثر شيوعًا لتساقط الشعر وبما أن الاضطرابات الغذائية هي أحد العوامل المحفزة له من ضمنها فيتامين دال حيث انه أحد الفيتامينات المهمة.فيتامين دال فد يكون مفيدًا في علاج تساقط الشعر الكربي ونظرًا للعدد المحدود من الدراسات وقلة
... Show Moreالمقدمة: تعد التهابات الجهاز التنفسي السفلي الحادة أحد الأسباب الرئيسية للمراضة والوفيات ، خاصة في البلدان النامية. هناك اختلافات عالمية كبيرة من ناحية اعداد الاصابات والمعالجات السريرية والنتائج ، بما في ذلك الوفيات.
هدف الدراسة: وصف السمات الديموغرافية ، محافظة الإقامة ، المهنة ونتائج السريرية لمرضى التهابات الجهاز التنفسي الحادة.
المرضى والطرق: تناولت دراسة بأثر رجعي 1009 مريض ، 406 مريضا كانوا مص
... Show More(2000) Summary:
(2001) Background: infertility is defined as the inability of a couple to conceive after one year of a regular unprotected intercourse with the same partner. Many factors seem to play a role in male infertility.
(2002) Aim: to evaluate the role of some seminal plasma biochemical components in male infertility.
(2003) Methods: seminal plasma of 100 infertile men & 25 fertile men were chosen as a subject of this study.
(2004) Different biochemical parameters that are related to oxidative stress were measured. These included Glutathione Peroxidase (GSHPX),superoxide dismutase (SOD),cerulopasmin (CP) scavenging activity, albumin & total sulfhydral (T-SH) & its individual parts (protein & non protei
Background:
Background:
Summary:
Background: the immune system differentiates between the endogenous and exogenous bodies that inter the body. The break-down of blood-testis barrier results in the production of antisperm antibodies. This may occur in the case of an infection to the prostate, seminal vesicle and epididymes. Antisperm antibodies (ASA) cause sperm agglutination and affect sperm motility, viability and sperm migration in the female reproductive tract. ASA also impair fertilization process. The objective of the present work was to study the effect of prednisolone on sperm motility index (SMI), viability and sperm penetration assay (SPA) in immunologically infertile men.
Materials and methods: The semen and serum samples of 140 infertile men we
Background:
Malignant renal neoplasm: Because benign tumors of kidney are rare, so it is a good rule that all neoplasm of kidney which are recognized clinically should be treated as malignant. They are uncommon between the ages of 7&40(l).Rcna! cell carcinoma is the most common tumor of the kidney in adult. It arises from renal tubular cells.. It is rare in children &is more frequent in men than women. It is an adenocarcinoma &is the most common neoplasm(75%) of kidney. The tumor may invade loca!Iy& metastasize by way of blood stream &the lymphatics. Regional lymph nodes are involved in approximately 30% of patients, unfortunately sign &symptoms are usually meager until the disease is advanced. Gross haematuria is the most fr
... Show MoreBackground:
Background:
Background:
Background: Interleukin-31 has been linked with developing and maintaining pruritus in various dermatological and non-dermatological diseases.
Objectives: To evaluate interleukin-31 serum levels in hemodialysis patients with and without uremic pruritus as a potential contributor.
Methods: This cross-sectional study involved ninety adult chronic kidney disease patients on hemodialysis. All of the enrolled patients were on a three-times/week hemodialysis regimen. Patients were divided into two groups of 45 patients each. Group 1 involved those with pruritus and Group 2 involved those free of pruritus; based on the itching severity scale (ISS). Serum levels of interleukin-31,
... Show MoreBackground: Catalase is an antioxidant enzyme found in all living organisms that is responsible for the degradation of hydrogen peroxide, a type of harmful compound known as reactive oxygen species (ROS), into harmless oxygen and water. It is necessary for cell protection from ROS-induced oxidative damage in type 2 diabetes mellitus (T2DM) individuals. T2DM is rapidly rising in prevalence worldwide, emerging as a significant public health challenge. It can disrupt iron regulation in the bloodstream, leading to the production of ROS, which can damage the cells.
Objective: To explore the correlation between iron status and catalase activity in T2DM patients, and the possibility of using it as a pred
... Show MoreBackground: Oxidative stress plays a major role in the pathogenesis of diabetes mellitus by damaging cellular organelles and enzymes in blood such as arginase1, insulin and glutathione s-transferase; increasing lipid peroxidation such as malondialdehyde and increasing insulin resistance which can lead to diabetic complications such as diabetic retinopathy.
Objectives: To explore the relationship of oxidative stress to the development of diabetic retinopathy by measuring the levels of Arginase1, the activity of glutathione s-transferase enzyme, and the levels of malondialdehyde as a secondary product of lipid peroxidation (biomarker for oxidative stress).
Patients and Methods
... Show MoreAbstract
Back ground: Renal cell carcinoma is an uncommon condition that develops during pregnancy. Due to a lack of conventional norms and a dearth of literature, its management is a serious issue.
Case presentation: We will discuss a case study of a twenty-year-old female girl who is pregnant G1 P1 A0, has had five missing periods (20 weeks gestation), and has frank hematuria due to a massive, incidentally detected renal cell carcinoma. We also go through the current guidelines for treating kidney malignancies during pregnancy, as well as the imaging studies that are now available.
Conclusion: Although the best time for surgery is debatable, a mult
... Show Moreلخلفية:الجوافة، هو نبات استوائي غني بالعديد من المكونات الكيميائية النباتية وله العديد من الاستطبابات التقليدية التي حددتها الدراسات السابقة. ينتمي نبات الجوافة إلى الفصيلة الآسية، أفادت العديد من الدراسات السابقة عن نشاط دوائي خاص ضد العديد من خطوط الخلايا السرطانية. الأهداف : تركز هذه الدراسة على عزل المركبات الفينولية من أوراق الجوافة المزروعة حديثاً في العراق وتقييم النشاط السام للخلايا لمستخل
... Show MoreBackground: Adenoid hypertrophy is one of the most common causes of nasal obstruction, and physicians use different methods to investigate it to reach a definite diagnosis.
Objectives: This study aims to determine whether there are clinical differences between grade II and IV adenoid hypertrophy and whether there is a positive correlation between adenoid-nasopharyngeal ratio and endoscopic examination findings.
Methods: This study was carried out on 120 patients; they were confirmed with five clinical tests (graded mirror, water-retention, lip-seal, deep-breath, and functional tests) and lateral cephalometric radiographs to measure the adenoid-na
... Show MoreBackground: Oral anticoagulation medication, warfarin and non-vitamin k antagonist oral anticoagulants (NOAC) may require long term use which may affect patients’ satisfaction with their treatment and their quality of life (QOL).
Objective: To compare the quality of life and treatment satisfaction among groups of patients using different anticoagulant therapies (warfarin and NOAC).
Patients and methods: A cross-sectional study was performed at Ibn Al-Bitar Hospital for cardiac surgery in Baghdad in the period between December 2022 to May 2023. The study population included a convenient sample of patients receiving either warfarin or non-vitamin k antagonist oral anticoa
Background: Oral anticoagulation medication, warfarin, and non-vitamin K antagonist oral anticoagulants (NOAC) may require long-term use which may affect patients’ satisfaction with their treatment and their quality of life (QOL).
Objective: To compare the quality of life and treatment satisfaction among groups of patients using different anticoagulant therapies (warfarin and NOAC).
Methods: A cross-sectional study was performed at Ibn Al-Bitar Hospital for cardiac surgery in Baghdad in the period from December 2022 to May 2023. The study population included a convenient sample of patients receiving either warfarin or non-vitamin k antagonist oral anticoagulants treatm
... Show MoreBackground: Birth trauma is defined as injury to neonates resulting from mechanical forces (such as compression or traction) during the process of birth. Birth injury is used to denote avoidable and unavoidable mechanical and hypoxic- ischemic injury incurred by neonates during labor and delivery. Maternal, labor and infant factors can predispose to birth traumas. Many types of birth traumas can be found including intra and extra cranial, spinal, peripheral nerves, fractures and visceral.
Patients and methods: A cross sectional study was done on 200 babies (100 babies for the study group and 100 babies for the control group), admitted to special care baby unit of Baghdad Teaching Hospital, during the peri
Background: Transitional cell carcinomas (TCC) of the bladder are a major health problem. Recently, some studies link high risk Human papilloma viruses' type 16 and type 18 with bladder carcinoma.
Materials and methods: Fifty formalin fixed, paraffin embedded tissues with TCC of the bladder from Specialized Surgical Hospital in Baghdad were included in this study. In addition, ten
apparently normal bladder autopsies were collected from the Forensic Medicine Institute Archives and used as control group. Tissue blocks were sectioned and sticked on charged slides and used for the detection of HPV-16 and HPV-18.
Results: The expression of HPV-16 and HPV-18 DNA signals in TCC of the bladder tissues in the&nbs
Background: In breast carcinoma, amplification &/or over-expression of HER-2/neu has been associated with a group of unfavorable prognostic factors. The Food & Drug Administration Agency approved Trastuzumab (Herceptin) for the therapy of metastatic breast cancer but only in patients with amplification &/or over-expression of this gene. Because of these advances, evaluation of HER-2/neu status in breast cancer specimens is of vital importance.
Patients and methods: thirty eight females with breast carcinoma were included in this study. All histologic sections were stained routinely with the hematoxylin and eosin stains and
immunohistochemically for HER2/neu. All cancers were graded and subcatego
Background: Many etiological factors have been implicated in the pathogenesis of Asthma like; viruses, bacteria and Chlamydia pneumoniae. This study focuses on the role of Chlamydia
pneumoniae in asthma pathogenesis.
Patients and Methods: The detection of Anti-Chlamydia pneumoniae antibodies IgA, IgM and IgG in patients by ELISA, for 35 patients, 18 asthmatic patients, 12 patients with chest infection with no history of asthma, and 5 apparently healthy as control subjects.
Results: The results showed that 80% and 70% of the patients were negative for anti- Chlamydia pneumonia antibodies IgA and IgM respectively, while significantly (p<0.05) high number (73%) of patients were positive for IgG, of which