Background: Cell adhesion molecules are protein entities that are located on the cell surface. The vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) expression is related to type 2 diabetes mellitus (T2DM) with dyslipidemia.
Objectives: To determine the levels of VCAM-1 and ICAM-1 in T2DM patients with dyslipidemia and to explore the relationship between VCAM-1 and ICAM-1 and the development of dyslipidemia in T2DM patients.
Patients and methods: The study included 150 individuals with an age range of (35-55) years. Patients with diabetes for more than 5 years were excluded. Fifty healthy individuals constituted Grou
... Show MoreBackground: The acquired immunodeficiency syndrome (AIDS) is a disorders caused by cellular and humoral immune dysfunction from infection by the human immunodeficiency virus (HIV 1 and HIV 2).
Patients and Methods: The study was carried out in Kirkuk governorate on 5090 secondary school students from different localities of the city, for the period from the beginning of October 2005 to the end of March 2006. A special questionnaire was applied for each student containing age, sex, class, parent’s education, mode of transmission & methods of prevention.
Results: There was no significant difference between male and female regarding the etiology of AIDS.The knowledge of secondary school students was
Background: Rheumatoid Arthritis (RA) is heterogenous syndrome. Because the diversity of disease processes and formation of complex lymphoid microstructures that indicate the multiple T cell activation pathways are involved .affected patients have major abnormalities in the T cell pool with clonally expanded CD4 + T cell that lose expression of the CD28null molecule and lack the ability for profiliration. Adenosine deaminase (ADA) is an indicator of the proliferation and differenation of lymphocyte, in particularly the T cell subcells.
Patients and Methods: Total ADA levels were measured in the sera of RA patients and healthy group according to Giusti (1981).
Results: The mean value of ADA was lo
Background: Many reports demonstrated an increase in low birth weight in the past three decades. This work was carried out to study the prevalence of low birth weight and its determinants among neonates delivered in Baghdad, Iraq.
Materials: A total of 400 singleton newborns delivered at two hospitals in Baghdad city during 15th June to 15th Nov. 2003 were included in the study.
Results: Half of the neonates were born with low birth weight. Out of the low birth weight neonates, there were 83% preterm neonates. Prevalence of low birth weight neonates was significantly associated with maternal age, age at marriage, parity, and anaemia.
Conclusion: This study indicates that the most appropriate approa
سرطان القولون والمستقيم (CRC) هو مرض شديد الخطورة يتسبب في مشاكل طبية سريعة التطور وله معدل وفيات مرتفع. يمكن تصنيف مُسْتَضِدٌّ مُنَاوِعٌ للنَّسيج (TPS) كمؤشر حيوي في سرطان القولون والمستقيم وأنواع أخرى من السرطانات. لوحظ ان لعامل نمو بطانة الأوعية الدموية (VEGF) دور علاجي في تكوين أوعية دموية جديدة. قد تساهم مثيلة الحمض النووي بتقليل انتشار السرطان. كانت هذه الدراسة مصممة لقياس الدور المحتمل لمستويات TPS و VGEF في
... Show MoreBackground: Mitochondria play an important role in the regulation of physiological type of cell death (Apoptosis) this type of cell death can be stimulated by two major pathways: external (Fas-Fas ligand interaction) and internal mitochondrial pathway which require disruption of mitochondrial transmembrane potential (ΔΨm ) which leads to opening of mitochondrial channels that lead to release of cytochrome –C which would execute apoptotic process.
Patients and Methods:The study included 32 normal subjects; 2 ml of venous blood were aspirated from each of them and processed for peripheral blood lymphocytes separation (PBL)
Then lymphocyte apoptosis was studied before and after exposing (PBL) to hypertherm
Background: Free radicals have been implicated in many pathological processes, including ischemia, inflammation, and malignancy. The free radicals may affect tissues damage by lipid
peroxidation which generate malondialdehyde (MDA) as a by byproduct of the reaction. The objective of this study is to examine the dynamics of lipid peroxidation in patients with
thyroid disorders using the measurement of malondialdehyde level as a marker for the degree of thyroid disorder.
Methods: Two hundred and forty five subjects were enrolled in this study. Hundred and ninety five were patients with different thyroid disorders (88 yperthyroidism, 63 hypothyroidism and 44 thyroid carcinoma) the remaining 50 subjects were
This study. was done on three hundred mothers who has a child less than 5 year old in ALNahryn University Teaching Hospital for the period of three months 1-1-2001 to 31-3-2001.
The study showed that 48% were Breast-feeding, 11% Bottlefeeding, & 41% Mixed breast and bottle-feeding. The family plays a major role (97.2%) in deciding the type of feeding
and the doctor role was only 2% in that regard and 21.2% in advice for artificial feeding. The study also showed that there is a decline in breast feeding among -the three generations
studied 100%, 96.4%, 48%; which represent around 52% o decline in breast feeding.
Background: Differentiating cytotrophoblasts transform their adhesion receptor phonotype so as to resemble the endothelial cells they replace a process that is required for normal placentation, and any defect in this adhesion phenotype switch might lead to pregnancy failure.
Patients and Methods: Curate samples of the materno-fetal interface were taken from 20 women with spontaneous first trimester abortion and 6 control women undergone elective termination of pregnancy in the first trimester. Immunohistochemistry analysis of paraffin embedded sections of these curate samples was performed using monoclonal antibodies for cytokeratin, PECAM-1 and VCAM-1.
Results: Cytokeratin showed positive immunostaing
Background: Rheumatiod factor in patients with Rheumatoid arthritis (RA) could be of IgM, IgG, or IgG isotypes.
Aim: To study the occurance of each or all these isotypes in RA patients .
Methods: Enzyme linked Immune Sorbent Assay (ELISA) & Latex agglutination test were used to asses RF in 74 patients with RA.
Results: Using ELISA, 58 (78.4%) patients had positive RF (IgM 48.6%, IgG in 47.3% & IgA in 54.1% ), while only 43 (58.1) patients were positive by AG .
Conclusion All RF isotypes should be assessed in patients with RA.
Back ground: Type 2 Diabetes mellitus (T2D) is a common complication of all liver diseases. However clinical and experimental data suggest a direct role of HCV in the perturbation of glucose metabolism. The aim of this study is to investigate the role of HCV infection as a risk factor to develop type 2 diabetes mellitus, and to study the immunopathogenicity of HCV in diabetes mellitus patients, through the assessment of IFN-γ, TNF- α and IL-10 serum levels.
Objectives: Is to investigate the role of HCV infection as a risk factor to develop type 2 diabetes mellitus, and to study the immunopathogenecity of HCV in diabetes mellitus patients, through the assessment of IFN-γ, TNF- α and IL-10 serum levels.
Background: Although studies regarding the role of religious beliefs in psychological well being are relatively recent, the importance of people’s religiousness and spirituality for their health status has been widely acclaimed based on hundreds of published studies.
Patients and Methods: The Arabic Modified version of WHOQOL-SRPB (World health organization quality of life-spirituality, religiosity and personal belief) questionnaire was self
administered to a systematic random sample of 100 fifth year medical students.
Results: Around a quarter (21-28%) of subjects perceived religiousness as very to extremely important. This percentage raised to 38% for spirituality and further to 61% for personal believes.
Background : It is quite accepted that interleukins (IL) in general play a crucial role in response to injuy , infection and on cogenic trans formation , among there are IL-6 and ILJO.
Aim of this study is to find out the possible role of IL_ and IL, 10 in colo rectaI carcima in Iraqi patients.
Subjects and Methods: forty patients with colorectal cancer (CRC) composed with 30 healthy controls were enrolled in this study. Serum conc. Of IL-6 and IL -lOwere estimated in both groups using ELIZA technique.
Results: Serem levels of IL-6 and IL-10 were significantly increased (P<0.001) in compassion with control group.
Conclusion: these cytokins could be used as a markers for tumor progression .
خلفية الدراسة: تعتبر القيلة السحائية أكثر حالات التشوهات الخلقية للجهاز العصبي شيوعا. وهي أكثر شيوعا في دول العالم الثالث. يكون العلاج عادة جراحي مع إحتمال كبير لحدوث مضاعفات واضحه.
الاهداف: لفحص الاسباب والمخاطر التي قد تؤدي الى مضاعفات في جروح عملية القيلة السحائية .
المرضى وطرق العمل: دراسة مستقبلية أجريت في م. الجراحات التخصصية,
... Show Moreالخلفيه: السمنة تمثل خطر كبير على الصحة العامة للانسان. بينت الدراسات في العراق ارتفاع في معدل انتشار السمنة بعد التحسن الاقتصادي وتغير نمط الحياة لدى الناس.
الهدف: تحديد انتشار السمنة بين النساء في مدينة الصدر- بغداد.
الطرق: دراسة مقطعية مستعرضة شملت 440 أمراءه من مرافقات للمرضى المراجعات للمركز لصحي وذلك بقياس مؤشر كتلة الجسم.
... Show MoreBackground: All medical colleges give students courses in epidemiology and biostatistics to help them in understanding medical data and to prepare them to conduct graduate and professional research. After graduation, understanding and correct application of the principles of epidemiology and biostatistics help the physicians in making better diagnostic and management decision based on best evidence.
Patients and Methods: A cross-sectional questionnaire-based survey was carried out among junior (chronic resident) doctors at several hospitals in Baghdad from the 1st of January till the 31st October 2009. A total of 212 physicians answered the questionnaire which covered demographic characteristics, average score
التمزق التلقائي لأغشية الجنين قبل بدء الولادة الذي يحدث قبل اكتمال 37 أسبوعًا من الحمل ، يشار إليه على أنه تمزق الأغشية المبكر قبل الولادة . يحدث في 2٪ من حالات الحمل. يعتمد التنبؤ بـه على تحديد عوامل الخطر المرتبطة واستخدام مؤشرات حيوية محددة لمنع النتائج الضارة على الام والجنين. ان الهدف من الدراسة لمعرفة العلاقة وفهم الدور بين حامض الفوليت ، فيتامين بي 12 والهميوسستين في تمزق الغشاء الامينوسي المبكر قبل حدو
... Show MoreJervell and Lange-Nielsen syndrome (congenital LQTS and hearing loss) isa rare inherited disorder characterized by deafness present at birth (congenital) occurring in association with abnormalities affecting the electrical system of the heart , Iron-deficient anemia and elevated levels of gastrin are also frequent features of JLNS1. The severity of cardiac symptoms associated with Jervell and Lange-Nielsen syndrome varies from case to case. Some individuals may have no apparent symptoms (asymptomatic); others may develop abnormally increased heartbeats (tachyarrhythmias) resulting in episodes of syncope, cardiac arrest, and potentially sudden death. Physical activity, excitement or stress may trigger the onset of these symptoms. Jervell
... Show Moreخلفية: السمنةآخذت في الازدياد في جميع أنحاء العالم بحيث ما يقدر بنحو ١.٧ مليار شخص يعانون حاليا من السمنة، حصاة المرارة تمثل المرض الثالث الأكثر شيوعا لدى المرضى الذين يعانون من السمنة المفرطة. وعلاوة على ذلك حوالي ٣٠٪ من المرضى المرشحين لجراحة البدانة إما خضعوا لجراحة استئصال المرارة بالسابق أو شخصوا بوجود حصاة المرارة اثناء التقييم قبل عملية جراحة البدانة.
الهد
... Show MoreBackground: Bariatric surgery (BS) is the most effective method for long-term weight loss. Rapid weight reduction after BS may contribute to the formation of gallstones.
Objectives: To assess the rate, and to identify the associated factors, of gallstone formation after laparoscopic sleeve gastrectomy.
Methods: This was a cross-sectional study among 128 patients with morbid obesity, who were treated with laparoscopic sleeve gastrectomy and followed up at two weeks, one month, six months, and one year after surgery between October 2018 and July 2020, at the Gastroenterology and Hepatology Teaching Hospital in Baghdad and the Dowaly Private Hospital. Data was collected using
... Show Moreالخلفية: يعد الإكتئاب من الحالات المزاجية الأكثر شيوعًا بين كبار السن والذي يتم ربطه بعواقب وخيمة مثل صعوبة التركيز واضطرابات المزاج، يليه قلة الإهتمام بالأنشطة الإجتماعية واللامبالاة والتشاؤم وتغيرات في الشهية والنوم.
الهدف من الدراسة: لتحديد مدى انتشار الإكتئاب والعوامل المصاحبة له بين كبار السن ممن أعمارهم 60 عاما فأكثر.
المنهجية: دراسة وصفية تحليلية مستعرض
... Show MoreBackground: The aim was to ascertain the current practice of adjuvant therapy for tonsillectomy and to determine whether it is evidence based.
Methods: A questionnaire answers were obtained from sixty otolaryngologists in Baghdad.
Results: There was no any enthusiasm for routine intra-operative local anaesthesia. Paracetamol (Acetaminophen) is prescribed by nearly all surgeons for postoperative analgesia,
and the current literature supports its efficacy and safety. Further, some practitioners combine paracetamol with NSAIDs, and/or Tramadol-Opioids. Evidence to support the additional use of these agents is, however non existent or limited. For the use of antibiotics, we found some of the otolaryngologist
Background: The purpose of the study is to determine whether the pre-treatment clinical systemic variables and optical coherence tomographic (OCT) findings are associated with the subsequent response to the intravitreal Bevacisumab (IVB) in eyes with diabetic macular edema (DME).
Patients and Methods: 38 patients (45 eyes) with refractory diabetic macular edema. ; 16 females, 22 males and mean age was 57.5 year. All patients had DME not responded to other treatments. Complete eye examination; BCVA* (represented as LOGMAR for adequate statistical analysis), slitlamp exam, intraocular pressure measurement, stereoscopic biomicroscopy of the macula, and morphologic patterns of diabetic macular edema demonstra
الخلفية: الإنتان الجرثومي في الأطفال حديثي الولادة سبب مهم ومتكرر للمراضة والوفيات في الأطفال الحديثي الولادة بالأخص في الدول النامية وحديثي الولادة قليلي الوزن .
الهدف : هدف الدراسة هو لتحديد العلامات السريرية, عوامل الخطر,المصاحبة للإنتان في الحديثي الولادة ولتقييم نسبة الوفيات الناتجة من الإنتان في الحديثي الولادة وعلاقته مع الوزن عند الولادة, عمر الحمل,بداية الإنتان ,نوع
... Show MoreBackground: the first stage ,labour is divided into early (latent phase )when uterine contractions are irregular and cervical effacement and dilatation are gradual, while the active phase of labour commences when cervical dilatation reaches (4) cm .and uterine contractions are more powerful . Our aim from this study is to see the effect of the timing of admission to labour room on mode of delivery and foetal outcome.
Patients and method: 240 nulliparous women at term pregnancy were diagnosed as labour pain and admitted to Baghdad Teaching Hospital from the first of January to the end of December 2006, they were followed during their course of labour to see the effect of admission to the labour room in&nbs
المقدمة : التطبيب الذاتي هو مشكلة عالمية ، لها تأثيرات سلبية خطيرة على الأفراد والمجتمعات
طريقة البحث : أجريت دراسة مقطعية وصفية بين طلاب الطب في جامعات الأنبار والفلوجة خلال الفترة من شباط إلى اذار 2018. وقد طُلب من المشاركين ملء استبيان يتكون من أسئلة حول العمر والجنس والمستوى التعليمي، بالإضافة إلى الأسئلة عن التطبيب الذاتي.
... Show Moreالخلفية: الحمى السوداء هو مرض طفيلي مهم يصيب الأطفال من جميع الفئات العمرية مع نتائج قاتلة إذا تركت دون علاج.
الاهداف: IFAT تمت دراسة الأطفال الذين أدخلوا المستشفى مصابين بالحمى السوداء لتقييم صلاحية اختبار
المرضى والطرق: أجريت دراسة مقطعية على 60 طفلا مصابين بالحمى السوداء الذين ادخلوا في مستشفى حماية الأطفال التعليمي في بغداد،
... Show Moreخلفية الدراسة :
لا يزال خمج السل الرئوي يشكل مشكلة صحية رئيسية على مستوى العالم، حيث تم تحديد مدى انتشاره بين سكان العالم بنسبة 32% مع زيادة 8 مليون من الحالات المشخصة الجديدة كل عام.
هدف الدراسة: تحديد مدى مقاومة الأدوية المضادة للسل الرئوي بين مرضى معالجين سابقا وكذا التركيز على ذريات المتفطرة السلية المعندة على عديد من الأدوية في
... Show Moreخلفية عن الدراسة: هناك عدة عوامل تجعل الورم النقوي المتعدد موضوعا هاما يستحق الدراسه من قبل الباحثين. وتشمل هذه الدراسات تقدما ملحوظا في فهم علم الأحياء الجزيئي لخلايا البلازما الطبيعية و الورمية والتطورات الحديثة في تقنيات الوراثة الجزيئية. بين المعلمات الجزيئية، القامع السرطان الجيني p53 قد درس على نطاق واسع.
الهدف من الدراسة: ربط التعبير البروتين
... Show More