Background: Chronic myeloid leukemia (CML) is a clonal stem disease with distinctive clinical course which is ultimately fatal. It is characterized by the presence of Philadelphia
chromosome (t 9:22).Tyrosine kinase inhibitors like imatinib mesylate as targeted therapy had revolutionized the management of CML with significant prolongation of overall survival and
decreased rate of blastic transformation.
Objective:This study will describe the experience of treating 44 Iraqi patients with chronic myeloid leukemia by imatinib at the National Hematology Centre in Baghdad.
Patients and Methods:This study included 44 Iraqi patients diagnosed in Chronic phase CML at the National Centre of Hematology in Baghdad fr
Background: Otitis media with effusion(OME)is a common cause of deafness in children with subsequent impairment of speech development and scholastic difficulties.Treatment
remains controversial.
Aim: To study the effect of amoxicillin-clavulanate in treatment of OME
Patients and methods: A prospective study of a target sample consisting of sixty children under the age of 12 years presented with chief complaints duration for at least 6 weeks and
on examination there were bilateral red and retracted tympanic membranes without oversized adenoids and no underlying causes require surgical correction e.g cleft palate.The
patients were divided into two groups;group A which received Actifed for 4 weeks and grou
Background: The present study was planned to show the accuracy of clinical examination and tympanometry in diagnosis of middle ear effusion.
Patients and Methods: The study involved 80 patients (160 ears )suspected to have otitis media with effusion (OME) from different age groups ; 56 were males and 24 were females .
Clinical assessment for all patients included otoscopy , pneumatic otoscopy and audiological assessment by using pure tone audiometry and tympanometry then comparing the results to
findings at myringotomy as the gold standard for presence or absence of fluid in the middle ear.
Results : Fluid whether serous or glue was found in 100 ears ( 62.5 %) where as sixty ears were dry, sensitivity , sp
Subject and Method :
study involved sixty five children with kala-azar who were admitted to the maternity and children teaching hospital in Diwaniah during a one year period , 1999. The
clinical and epidemiological criteria of the disease were discussed. The majority of these patients were under the age of 5 years ( 97% ) and were from rural areas ( 86% )
Result :
The symptoms and signs of the disease were fever (100% ), splenomegaly (100% ), anaemia ( 100% ), hepatomegaly ( 92% ), anorexia ( 62% ), bleeding tendency ( 46%
) and jaundice ( 31% ). Our patients had high incidence of bleeding tendency , jaundice , edema and relatively high mortality in comparison with patients elsewhere
Backround:
chlorhexidine mouth wash one of the effective chemical plaque control method that is used to prevent plaque accumalation and subsequent gingivitis.
خلفية البحث: بالرغم ان سرطان الثدي في النساء الشابات هو أقل شيوعا، وغالبا ما يغفل عنه، فإنه لا يزال يعتبر مصدر قلق صحي رئيسي.
اهداف البحث: تقييم الخصائص الديموغرافية والسريرية والتصويرية والنسيجية المرضية لسرطان الثدي لدى عينة من النساء العراقيات اللاتي تقل أعمارهن عن 40 عاما.
المرضى والطرائق: طبقت الدراسة بأثر رجعي على إناث دون سن 40
... Show Moreالخلفية: سرطان الثدي هو اكثر الامراض السرطانية شيوعا في العالم والسبب الرئيسي للوفاة بسبب السرطانن بين النساء عبر العالم.
HER2المقدمة: الهدف من الدراسة لمعرفة امكانية السونار في تحديد نتائج الفحص النسيجي لسررطان الثدي وتكهن حالة ال
المرضى والطرق:أجريت هذه الدراسة عن طريق الاختيار الرجعي ل 102مريض شخصوا باصابتهم بمرض سرطان الثدي خضعوا
... Show Moreخلفية الموضوع: جلد الأنسان هو العضو الأكبر للنظام أذ يتكون من طبقات متعددة من أنسجة البشرة تحتها عضلات وعظام وأعضاء داخلية أخرى. النخالية المبرقشة هو مرض جلدي سببه يعود لفطر المالاسيزيا. نوع Malassezia furfur هو السبب الرئيسي للمرض والذي يسبب تغيرات لونية أعلى وأسفل الجلد.
الهدف: تشخيص الفطر المدروس المصاحب لمرضى النخالية المبرقشة والأشخاص الأصحاء بأستخدا
... Show Moreالنظري: تعتبر الالتهابات وبصورة أكثر تحديدا السيتوكينات الالتهابية مقياسا مهما في تطور مضاعفات السكري كالاصابة بامراض الاوعية الدموية الدقيقة ، بالاضافة لذلك اعتلال الأعصاب ، اعتلال الشبكية و اعتلال الكلية .
الهدف: صممت هذه الدراسة لتقدير العلاقة بين بروتين سي الفعال العالي الحساسية والزلال البولي وأعتبارهما عامل خطورة للاصابة بأمراض القلب بين (30) مريض من
... Show MoreJervell and Lange-Nielsen syndrome (congenital LQTS and hearing loss) isa rare inherited disorder characterized by deafness present at birth (congenital) occurring in association with abnormalities affecting the electrical system of the heart , Iron-deficient anemia and elevated levels of gastrin are also frequent features of JLNS1. The severity of cardiac symptoms associated with Jervell and Lange-Nielsen syndrome varies from case to case. Some individuals may have no apparent symptoms (asymptomatic); others may develop abnormally increased heartbeats (tachyarrhythmias) resulting in episodes of syncope, cardiac arrest, and potentially sudden death. Physical activity, excitement or stress may trigger the onset of these symptoms. Jervell
... Show Moreخلفية البحث :مرض متعددة تكيس المبايض هو المرض الاكثر شيوعا عند النساء في سن الانجاب الذي يرافقه اضطرابات في الوظائف الانجابية,الهرمونيةوالايضية.ويبدو ان الفيزيولوجيا المرضية لمرض متعددة تكيس المبياض هي ذات عوامل متعددة وجيناتية. يبدو انه بالامكان استخدام مستضد البروستات المحدد كعلامة لفرط الاندروجينية في النساء الذين لديهم مرض متعددة تكيس المبايض
الاهداف <
... Show Moreالخلاصة: في السنوات الأخيرة، هجرة بطانة الرحم تؤثر الى ما يصل إلى 10 في المئة في النساء العراقيات بعمر الانجاب. ولا يعرف سوى القليل عن مسببات بطانة الرحم المهاجرة في النساء العراقيات.
الهدف: CoQ10كان الهدف من هذه الدراسة هو التعرف على التغيرات
... Show Moreخلفية الدراسة: المركبات العضوية الاروماتية متعددة الحلقات مجمعوعة من المركبات العضوية التي توجد في الاطعمة الغنية بالبروتينات حيث تتكون خلال بعض عمليات الطبخ والشواء . مركب بنزو (أ) بايرين هو احد مركبات هذه المجموعة والتي تحتوي في صيغتها البنائية الكيميائية على حلقتين اروماتيتين متجاورتين او اكثر متصلة ببعضها بذرتي كاربون او اكثر صيغته الجزيئية هي C20H12 . ما موجو
... Show Moreالخلفية العلمية: اصابة الضرر الدماغي قد تحدث في مجموعة متنوعة من الحالات الصحية، وهذا لا يزال يمثل مشكلة كبيرة. لذلك، يبدو من الممكن أن استعمال المستخلص المائي الجنكه بيلوبا في حماية المخ من الإصابةخلال نقص التروية واعادة ضخه.
الهدف: شملت الدراسة معرفة المكونات الكيميائية في المستخلص المائي لنبات الجنكة بيلوبا وتحديد ما اذا كان يمنع او يقلل الت
... Show Moreالخلفية: اصابات الغضروف المفصلي في مفصل الركبة تشاهد في كثير من الاحيان، علاجها يمثل تحدي لجراحي العظام والكسور وخاصة عند المرضى الشباب، واذا تركت بدون علاج فممكن ان تؤدي الى سوفان متقدم يؤثرعلى الحالة الوظيفية للمرضى. العديد من طرق العلاج وجدت لهذه الاصابات، في هذه الدراسة تم استخدام طريقة الكسور الدقيقة بالناظور مع زرق نخاع العظم الكامل في المفصل كأحد طرق العلاج لهذه الاصابات.
... Show Moreمقدمة : لاورام السرطانية قليلة الحدوث في حالات تضخم الغدة الدرقية الغروي المتعدد مقارنة مع نسبة حدوثها في حالات التضخم الدرقي الناتج عن عقدة درقية احادية.
الخلاصة: نسبة حدوث الاورام الخبيثة في التضخم الدرقي الغروي المتعدد تصل الى 8.7% . تعتبر عملية قص الغدة الدرقية قريب الكامل او الكامل الاختيار الافضل في علاج حالات التضخم الدرقي الغروي المتعدد لانه سيقلل من الحاجة لاعادة عمل
... Show Moreالمقدمة: يعتبر سرطان القولون واحدا من اكثر الاورام الخبيثة شيوعا و انتشارا, و السبب الثاني للوفاة بسبب السرطان في العالم الغربي.
ينتمي مستقبل عامل النمو البشري الى عائلة ( Erb-B ) مستقبلات التايروسين و يلعب دورا مهما في تطور سرطان القولون و المستقيم.
هدف الدراسة:تحديد نسبة و شكل التعبير المناعي لمستقبلات عامل النمو البشري في السر
... Show Moreخلفية البحث:-يعتبر الإستعمال العكسي لمادة الكارديوبليجيا واسع الإنتشار في حماية عضلة القلب لعمليات زرع الشرايين التاجية في القلب و مختلف عمليات القلب المفتوح بالإضافة إلى الطريقة التقدمية (الأمامية) لمادة الكارديوبليجيا.
الهدف من البحث:-لتقييم إستعمال الطريقة العكسية لإعطاء مادة الكارديوبليجيا و فوائده في عمليات زرع الشرايين التاجية للقلب في مستشفى إبن ال
... Show MoreBackground: HROM agar Orientation is a chromogenic medium used for the detection and differentiation of Gram’s negative and Gram’s positive pathogenic microorganisms in urine samples. Evaluation of CHROM agar Orientation for identification of urinary pathogens and susceptibility determinations in comparison to the ordinary media used.
Patients and Methods: A total of 375 midstream urine sample collected from patients with urinary tract infection (UTIs). CHROM agar Orientation, blood agar and macConkey agar media were used for direct inoculation.
Results: CHROM agar Orientation succeeded in detecting all the urine pathogens that were detected by the reference media, and antimicrobial Susceptibility
Background: Cutaneous small vessel vasculitis characterized by necrosis and inflammation of upper dermal blood vessels. It presents with ulcers and systemic manifestations after extensive acute onset. Many patients have a form of cutaneous vasculitis that presents with chronic painful ulcerations & purpuras involving the ankles without systemic manifestations, with some similarity in clinical presentation to livedoid vasculopathy.
Patients and Methods: Thirteen patients were seen in the Department of Dermatology and Venereology, Baghdad Teaching Hospital, for a period extending from January 2004 to March 2005. They were evaluated clinically, histopathologically and other laboratory studies. In additio
Objectives: a study of surgical procedures used in the management of sciatic n injury & acomparism between them including comparism with other universal studies.
Patients and methods: 62 patients collected from the neuro-surgical unit in the specialized surgical hospital from Jan-2004 till October 2007, all patients studied thoroughly regarding age, Gender, type of injury, time of injury & outcome.
Results: 85% of our patients were ♂, 45% were in the age of 21-30 years, most injured by bullet or shells, the delay in surgery was mostly 1-3m, the repair is by direct suture 45%, 29% release of adhesions 16%, excision of neuroma & suturing, 9.6% by nerve graft, the direct suturing carried the 
Background: Mitral stenosis (MS) is the most common valve disease in developing countries and there are many ways to deal with this condition. The aim of this study was to evaluate the immediate results of percutaneous transvenous mitral commissurotomy (PTMC) in patients with severe symptomatic rheumatic mitral stenosis.
Patients and Methods: From May 2006 to August 2007, 58 patients (17 male, 41 female) with age range (16-57) years, underwent PTMC in Ibn AL- Bitar Hospital for Cardiac Surgery. All the patients were symptomatic, their MVA 1.5 cm2 with NYHA class II-IV. Clinical evaluation and echocardiographic examination were carried out before and after PTMC, mitral valve structures were assessed
Background: The acute phase response is a major pathophysiologic phenomena that accompanies inflammation whether acute or chronic. The complements 3 (C3), complement4
(C4) and C-reactive protein (CRP) are positive acute phase proteins (+ve APPs) their production is increased by hepatocyte in osteoarthritis (OA). Chloroquine (CQ) which is a diprotic weak base traditionally used to treat malaria.Todate, the phosphate salt of CQ is used to decrease +ve APPs.
Objective: To evaluate the role of chloroquine phosphate on acute phase proteins C3, C4 and Creactive protein in patients with knee OA.
Subjects and methods :A total of seventy four patients (45 female and 29male) were selected randomly from the outpati
Free – living or limax amoebae are small free-living protozoans which exist in fresh water and soil environment. These amoebae were found infective to man causing a fatal disease affecting the central nervous system. Fowler and Carter were the first to report four fatal human cases of acute pyogenic meningitis caused by free-living amoebae1. The genera Naegleria and Acanthamoeba are incriminated in such infections2. Swimming in contaminated water has been frequently postulated as the way of infection through the intranasal mucosa. Since
that time more than one hundred cases of primary amoebic meningoencephalitis were reported from different parts of the world. On&
Background: Among different lifestyle factors, aging process can adversely affect male semen parameters and hence male fertility in this study, semen parameters and productive hormonal profiles of subfertile young men were compared with subfertile middle and old age men.
Background: The use of the chest x-ray measurements which includes the cardiothoracic ratio(C-T) and frontal area (FA) of the heart by the CXR are useful measures for primary assessment of the cardiac dysfunction.
Patients and Methods: A Prospective study was done from the 1st of January 2005 to the 1st of October in the same year on a 120 consecutive patients who have been admitted for coronary and L.V angiogram at IBN-AL-BITAR hospital. The C-T ratio and the frontal area were measured.
Results: The study comprised 120 subjects who were admitted for coronary and L.V angiogram for diagnostic reasons. 89subjects (74.2%) are male and 31subjects (25.8%) are female .17(14%) subjects have left ventricular d
Background: Unilateral sinonasal disease is commonly encountered during the practice of the otolaryngologists, the etiology include a wide variety of diseases ranging from simple
acute inflammation to highly malignant diseases. The clinical, computed tomography and histopathology differs between inflammatory and neoplastic diseases.
Patients and Methods: A prospective study carried out at the Otolaryngology department, Baghdad Medical City, Hospital of specialized surgeries between Jan.2007 to Nov.2008.The study involved 114 patients with symptoms and signs of unilateral sinonasal disease, a careful history, complete clinical examination and radiological investigations were done to all patients as well
Background: Chronic obstructive pulmonary disease (COPD) is a progressive airflow limitation that is preventable but not curable. It is associated with persistent symptoms that cause a considerable burden on individual productivity at work, and daily activities, and reduced quality of life, also burdening the healthcare system and society.
Objectives: The study aims to measure the burden of COPD on patients in terms of daily activities and work productivity. It also seeks to investigate some inflammatory biomarkers' levels and their correlation with selected outcomes.
Methods: A cross-sectional study on 120 stable COPD patients who were diagnosed and treated according to the GO
الخلفيه : استنشاق الجسم الغريب حاله طارئه وخطره خاصه فى الاطفال وهي ظاهره شائعه في العراق ويواجهها يوميا اطباء جراحة الصدر
الهدف : هو تسجيل حاله نادره لاستنشاق جسم غريب منسي قبل 15 سنه ومقارنة ذلك ببحوث اخرى
الطرق :تفاصيل الحاله السريريه والشعاعيه وطريقة رفع الجسم الغريب تحت التخدر العام
... Show MoreBackground: Cell adhesion molecules are protein entities that are located on the cell surface. The vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) expression is related to type 2 diabetes mellitus (T2DM) with dyslipidemia.
Objectives: To determine the levels of VCAM-1 and ICAM-1 in T2DM patients with dyslipidemia and to explore the relationship between VCAM-1 and ICAM-1 and the development of dyslipidemia in T2DM patients.
Patients and methods: The study included 150 individuals with an age range of (35-55) years. Patients with diabetes for more than 5 years were excluded. Fifty healthy individuals constituted Grou
... Show More