تم تصميم هذه التجربه لتقييم الدور الوقائي لزيت بذور الرمان (PSO) في حماية الكبد ضد السمية الناجمة عن فلوريد الصوديوم (SF) في الجرذان. قسمت عشرون من اناث الجرذان البالغات إلى أربع مجموعات متساوية وعوملت يوميا لمدة 40 يوما على النحو التالي: مجموعه السيطرة C اعطيت ماء الحنفيه ، المجموعه الثانيه T1 تلقت فلوريد الصوديوم 120 جزء في المليون في مياه الشرب ، المجموعة الثالثه T2 اعطيت كلا من فلو
... Show MoreA total of 16678 records of age at first calving and ages at next calving ,
in addition to 14058 records of calving interval belonged to Holstein cows were
analysed over period from 1992 to 2003 , at the Nasr Dairy Cattle Station,
United Company for Animal Resources Ltd., Al-Soueira ( 50 Km South of
Baghdad ). Data was analaysed using General Linear Model within the SAS
program to study the effects of some fixed factors on the studied traits .
Components of variance for the random effects was estimated by the
Minimum Variance Quadratic Unbised Estimation Procedure ( MIVQUE ) , also
phenotypic trend was estimated for all traits .
The overall means for age at first calving till the age at sixth calving were
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The present study was carried out to investigate the effect of oral administration of hot aqueous extract of beetle cocoon Larinus maculatus Faldermann, in a two doses 50
and100mg/Kg/Bw for 25 and 45days respect- tively on some organs such as liver, lung, kidney, intestine, heart, spleen, and brain in male mice Mus musculus. The results indicated that there were toxicopathological changes in many tissues of experimental animals. Histo -pathological changes was dose and period dependent . It was found that the aqueous extract of beetle cocoon has undesirable effect at the administered doses, since the raw extract of this cocoon is currently being used in Folk medicine as treatment for cough, bronchitis in Iraq. This study revealed that
إن الهدف من تصميم البحث هو لتقييم إمكانية إصلاح عيوب غضروف القصبة الهوائية في الكلاب .استخدمت في هذه الدراسة 18 من الكلاب المحلية ومن كلا الجنسين . قسمت إلى مجموعتين متساويتين. تم استحداث أذى في الجزء العنقي من القصبة الهوائية على شكل نافذة وبقطر حوالي 3سم * 2سم . تم غلق الأذى في المجموعة الأولى باستخدام مادة اسمنت العظم الصناعية مع شبكة البولي بروبايلين والمجموعة الثانية باستخدام شبكة البولي بروب
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This study aimed to assess the hepatoprotective efficacy of quercetin against hepatotoxicity induced by cyclophosphamide in a rat model. A total of 28 male Wister albino rats (Rattus norvegicus), with body weights ranging from 195.5 to 198.2 g and approximately three months of age, were randomized into four different groups: the untreated Control group received no interventions; the CYP group was treated with an intraperitoneal injection of cyclophosphamide at a dose of 200 mg/BW; the Qt group received an oral administration of quercetin at 100 mg/kg BW daily for ten days; and the combined (Qt+CYP) group received quercetin orall |
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Colorectal cancer ranks as the third most commonly diagnosed cancer and the second leading cause of cancer-related deaths globally. Fluoroquinolones, particularly Levofloxacin, have garnered interest for their potential anti-cancer effects, primarily due to their high affinity for metallic ions like copper. This affinity enhances their spectrum of activity and enables greater interaction with DNA in cancer cells, thereby inhibiting proliferation. Building on our prior work, where we synthesized copper-modified Levofloxacin (MOLVX), this study explores its therapeutic potential in treating precancerous colorectal lesions, known as Aberrant Crypt Foci (ACF), in a murine model. Sixty female Balb- |
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Muco-adhesive gel formulations are advantageous in extending the stay at the nasal absorption place, promoting drug absorption. Frovatriptan succinate (FVT) exhibits a 35% oral bioavailability and undergoes hepatic metabolism, making it a viable candidate for nasal delivery. This study aimed to assess novel FVT intranasal formulation for brain targeting in rat animal models. A total of 78 female rats (Rattus norvegicus domestica, Wister albino rats) were randomly divided into three groups: group A (considered a negative control), group B (includes 36 rats given FVT IV solution), and group C (includes 36 rats given FVT binary ethosome in situ gel intranasally). Drug level |
Foot and mouth disease (FMD) virus type 0 was isolated from blood of two dead
... Show MoreThis study was designed to investigate the prophylactic effect of aqueous
extract of black currant concentrate on some biological markers related with
heart disease in male rat treated H2O2. It also aimed at comparing the
prophylactic effect of black currant concentrate to that of vit E.
Forty adult male rats were divided randomly into equal groups (ten
rat/group) & were treated as follows for 42 days. Rats in the first group (G І)
were received normal water with oral intubation of sun flower oil 1ml /rat and
consider as control group. Animals of the second group (G Π) were received
0.5% H2O2 in drinking water, while rats of the third group (G Ш) were received
0.5% H2O2 in drinking water with oral intuba
This study was carried out to at the poultry farm of the college of
veterinary medicine / Baghdad University during 12/5/2004 – 6/7/2004 to
study the effect of substitution of smut wheat instead of intact wheat in
poultry ration at the following levels (0%, 25% , 50% and 100%)
representing the following groups (T0, T1, T2 and T3), respectively. Physical
treatment was obtained for smut wheat by polishing the seed by sand to
remove the superficial fungal growth. Each group was sub divided into two
sub groups, one was physically treated with sand and the other was not
treated to study the hematology traits at 28 and 56 days of the experiment.
Characterristics included in this study were PCV, Hb, RBC, WBC,
dif
The aim of this study to investigation the effect of Anaplasma spp.
infection on some blood parameters by collecting 65 blood samples
from Awassi local breed sheep. The total infection rate 26.15 % which
divided into 25 % in males and 26.31 % in females. The parasitemia
range between 0.5-4 % (mean 1.97 %).
The infected animals showed anemia represented by decrease means
of packed cell volume (P<0.01), red blood cell count (P<0.05) and
haemoglobin concentration, While increase corpuscular volume,
corpuscular haemoglobin and corpuscular haemoglobin concentration
(P<0.05). As well as decrease total white blood cell count and monocytes
while increase lymphocytes, neutrophils , eosinophils, basophils and
The aim of this study was carried out to demonstrate the cross-immunity
between Nocardia asteroids and Salmonella typhimurium antigens in mice.
18 mice, from both sex,were randomally divided into three groups equally.
the first group immunized subcutaneously with 0.0 5 micrometer / animal of
Nocardia asteroids antigen and abooster dose of the same antigen was
injected after week of the first dose. The second group was treated as the
first group with Salmonella typhimurium antigen. .The third group was
served as non-immunized control group. Delayed hypersensitivity and tube
agglutination test were checked at 30 days post-immunization. By using
Nocardin and Sallmonelin antigens.
The results revealed that the a
The study included 300 unsexed broiler chicks (Hubbard) were used to evaluate (Roselle Flower) as a feed additives on the productive performance of broiler. The chicks were divided into five groups with three replicates (20 birds in each) and fed on five diets. Diet 1 (control group) dried Roselle flower powder were supplemented to the diet 2, 3, 4 and 5 as 0.25, 0.5, 0.75 and 1% respectively. The result revealed that a significant (P<0.05) increase in body weight, body weight gain, feed consumption and improvement in feed conversion ratio. Although the differences between groups for edible parts percent were not significant (Heart, Liver and Gizzard). The hematological values PCV%, RBC, WBC and H/L ratio were increased significantly
... Show MoreMagnetic therapy was applied in the present study, which play two roles; as antimicrobial (Escherichia coli, Staphylococcus auras, Streptococcus spp, Klebsialla ,and Pseudomona ) and as stimulator to tissue repair.24 rabbits were used in this study, they divided into two groups; 1st group(treated group) contains 20 rabbits, 2nd group (control group) contains 4 rabbits, the last subdivided into two subgroup (standard control subgroup and sham-control subgroup, the left side of all animals in control group is standard control subgroup, while the left side is sham-control subgroup). After surgery to all, the wounds were exposed to pulsed magnetic field except standard control subgroup, they healed with conventional treatment, 1st group(trea
... Show MorePulsed electric field (PEF) processing involves the application of pulses of voltage for less than one second to fluid products placed between two electrodes. So this study was conducted for the quantitative assessments of mild PEF conditions on acid tolerance, growth, bile tolerance and protease activity of Lactobacillus delbrueckii ssp. bulgaricus LB-12. The control and PEF treated samples were prepared by inoculating 10 ml of freshly thawed culture of Lactobacillus delbrueckii ssp. bulgaricus LB-12 into 990 ml of sterile 0.1% (wt/v) peptone water and treated in a pilot plant PEF system (OSU-4M). The treatments were positive square unipolar pulse width of 3 μs, pulse period of 0.5 second, voltage of 1 kV/cm, delay time of 20 μs and f
... Show MoreThis study was undertaken to prepare Heat Killed Candida albicans Antigen (HK-CA) and to investigate it's effect on elicitation of Delayed-type Hypersensitivity (DTH) and protection from virulent Candida challenged in mice, and described the major effect of Nocardia on the immunogenicity of this Ag.Four groups of 6 males Swiss mice for each group were immunized intraperitonialy(I.p)for 10 days at 5 doses(one day intervals) with 1x108 HK-CA plus Nocardia cell sap as adjuvant(CFA),the second group immunized with HK-CA plus Freund incomplete adjuvant,the third group immunized with HK-CA only and the fourth group treated with normal saline. Another group of 6 animals was immunized intranasally(I.n)with HK-CA only with the same doses as previ
... Show MoreThe laboratory studies of the cultural isolation revealed that two isolates of Lactobacillus acidophilus were isolated from five soft cheese samples that were manufactured locally according to the farmers production procedure .Colonies of E.coli O157:H7 were isolated from raw milk samples by a conventional direct plating on selective enrichment CT-SMAC agar and tested serologically for the presence of O157 and H7 antigens using the commercial available latex agglutination kits .The results revealed that E.coli O157:H7 was resist to the crude bacteriocin that was extracted from L .acidophilus isolate NO.1 due to the nature of their cell wall, while when the outer membrane of E.coli O157:H7 was injured by cooling at 4°C for 6 hours , the
... Show MoreThis study is conducted to establish the profile of some serum biochemicals which included creatinine, urea, glucose, total protein and albumin concentrations in 104 clinically normal donkeys (65 males and 39 females) aged 2-4 years. Animals were classified on the basis of age and sex, in Baghdad city/ Iraq. The Results showed that the, mean values ± standard error (SE) of serum creatinine and urea concentrations were as follows: Creatinine 65.55±2.01 µmol/L and urea 6.79±0.20 mmol/L, while serum concentrations of glucose, total protein and albumin were 54.7±3.09 g/dl, 123±14.3 and 3.4±0.08 mmol/L, respectively. Creatinine values showed a significant difference between 4 years and more than 4 years old sub
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The goal of this study was to assess the antibacterial efficiency of biogenic silver nanoparticles (AgNPs) and gentamicin against Staphylococcus aureus that can form biofilms. The characterization of AgNPs was confirmed by the scanning electron microscope (SEM) which was spherical and homogenous in form, with a diameter between 25 and 45 nm. The X-ray diffraction (XRD) presented the size of AgNPs to be 50 nm. Energy dispersive spectroscopy (EDS) was used to examine the presence of elemental silver. The three-dimensional structure of silver nanoparticles was discovered using an atomic force microscope (AFM), with a diameter of 47.18 nm on average. The minimum inhibitory concentrations (MIC) and mi |
صممت الدراسة للتحري عن التأثير الفيزيائي الحياتي للأشعة الكهرومغناطيسية على الجهاز التناسلي الذكري للفئران البيض وعلاقتها بتغير كثافة القدرة بوحدات مايكروواط / سم2، وأظهرت نتائج الدراسة الحالية حصول انخفاض معنوي (P<0.05) في عدد النطف في البربخ وزيادة معنوية في النسب المئوية للنطف الميتة والمشوهة عند الجرع 100 و150 و200 مايكروواط /سم2 عند التعريض لمدة (30) يوما ولمدّة (6) ساعات يوميا
... Show MoreThis research aimed to evaluate the protective ability of Syzygium aromaticum methanolic extract against Salmonella Typhimurium infection in rabbits. Three groups of eight rabbits were given the following: The first group was subcutaneously given Salmonella
Typhimurium-whole sonicated killed antigen (ST-WSKAg); the second group was orally given S. aromaticum extract as well as KWCSAg-ST subcutaneously; the third group was left as positive control group. The rabbit groups were orally challenged by 9×108 CFU/mL Salmonella Typhimurium then the animals were sacrificed 10 days postchallenge for histopathological study. Intestine, liver, kidney, and spleen were studied for pathological changes. The results showed that the second group ha
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Physiological status and litter size can indeed have a significant impact on ewes' hematological parameters, which are essential indicators of their health. Therefore, this study examined the hematological profiles of ewes during pregnancy with single and twins in the Awassi ewes. The present study involved 232 ewes in good health and at sexual maturity. Among them, 123 ewes had single pregnancies, while 109 ewes had twin pregnancies. The age range of the ewes included in the study was between 3.5 and 4.5 years. Hematological tests were conducted on the sheep's blood samples promptly following collection. The findings demonst |
A synthetic prostaglandin F2 α(PGF2 α) analogue, luprostiol* , was used in treatment of clinically anoestrus Arabian mares that suffered from abnormal persisting luteal function. Thirty two anoestrus mares were selected for this study after careful examination of their breeding history and a thorough genital examination which included rectal palpation of the genital tract and ovaries. The genital examination also included a vaginoscopy of the vagina and cervix. These mares were diagnosed as clinically anoestrus during the spring and summer months breeding season and received a single intramuscular injection of the prostaglandin F2 α. Twenty six mares (81%) responded to the treatment and came to oestrus with
... Show MoreA total of 300 one day old unsexed broiler chicks were divided into three
dietary groups which were: -
T1: Un-treated control.
T2: Poultrygrow 250 treated group.
T3: Cr-Yeast treated group.
Results have shown that the addition of Poultrygrow 250 and Cr-Yeast
have significantly (p < 0.05) improved the performance of broilers express in
weight gain and feed conversion ratio compared with control group. The study
showed an increase in red blood cell and hemoglobin and reduce in hetrophil /
Lymphocyte ratio.It was concluded that the supplementation of poultrygrow 250
and Cr-Yeast in the diet of broiler chickens could improve the performance of
the birds.
This study concerned with prevalence of infection of the goats and their kids with coccidia during the period from 1st March 2004 to 30th February 2005. Three hundred fifty two faecal samples were collected from 32 goats. The rate of infections in goats and kids was 47.6%, 61.1% respectively. The peak of infection was in spring and winter, and then the infection declined in hot and dry summer. The rate of infection in females (33.3%) was higher than in males (14.2%). Four species of coccidia were diagnosed Eimeria ahsata, Eimeria faurei, Eimeria pallida, and Eimeria ovinoidalis.
The present investigation aimed to study the Adenosine Deaminase activity in induction Cytogentic and histopathological c
This study was conducted to investigate the hypolycemic effect of the aqueous
extract and some active ingredients of Nigella Sativa seeds in normal rabbits. Twenty
four male rabbits were divided into six equal groups. The first five groups were received
by gavage needle 160,240,320,400 and 480 mg/kg B.W. of the aqueous extract, while
the sixth group which served as control received normal saline solution. After two hours
of administration, the group which received 320 mg showed the lowest blood sugar level
as compared to control and other treated groups. This dose was considered for the next
studies.
Lectin was isolated from Nigella Sativa seeds by 0.2M phosphate buffer containing
0.15M NaCl at pH 7.0, and the
In order to know the cross –protection between antigene of T.rubrum and
C.albicans,17 mice were used and they were divided into (3) groups,1st group(7
animals) was immunized with T.rubrum antigen,two doses, and injected S/C
with virulent C. albicans,the 2nd group (5 animals) was infected with
C.albicans and considered as positive control,3rd group was served as negative
group which injected 0.5 ml of sterile normal saline s /c The results showed
that the antigen of T.rubrum stimulated a good immune response in
immunized mice against C.albicans.
The present study was carried out to investigate the effects of Ochratoxin A (OTA) on the serum activity of AST, ALT and ALP, Glutathione (GSH) and liver, kidney and spleen histopathology .Twenty male rats divided equally into three treated groups dosed orally and daily with OTA doses (70, 140 and 210 μg/kg) for 20 day representing T1, T2 and T3 groups and the fourth group dosed daily with distilled water considered as control one. Biochemical result showed elevation in AST and ALT activity and decrease in ALP enzyme activity and GSH serum concentration of treated serum groups at 10 and 20 days of exposure to ochratoxin A these changes positively were proportional with increase OTA doses (dose dependent). Histopathological changes were
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