In this article, unless otherwise established, all rings are commutative with identity and all modules are unitary left R-module. We offer this concept of WN-prime as new generalization of weakly prime submodules. Some basic properties of weakly nearly prime submodules are given. Many characterizations, examples of this concept are stablished.

Let R be a commutative ring with unity and let M be a left R-module. We define a proper submodule N of M to be a weakly prime if whenever  r  R,  x  M, 0  r x  N implies  x  N  or  r  (N:M). In fact this concept is a generalization of the concept weakly  prime ideal, where a proper ideal P of R is called a weakly prime, if for all a, b  R, 0  a b  P implies a  P or b  P. Various properties of weakly prime submodules are considered. 

      Let R be a commutative ring with identity and M be an unitary R-module. Let (M) be the set of all submodules of M, and : (M)  (M)  {} be a function. We say that a proper submodule P of M is -prime if for each r  R and x  M, if rx  P, then either x  P + (P) or r M  P + (P) . Some of the properties of this concept will be investigated. Some characterizations of -prime submodules will be given, and we show that under some assumptions prime submodules and -prime submodules are coincide. 

     Let  be a commutative ring with identity, and a fixed ideal of  and  be an unitary -module. In this paper we  introduce and study the concept of -nearly prime submodules as genrealizations of nearly prime and we investigate some properties of this class of submodules. Also, some characterizations of -nearly prime submodules will be given.

    In this paper, the concepts of -sequence prime ideal and -sequence quasi prime ideal are introduced. Some properties of such ideals are investigated. The relations between -sequence prime ideal and each of primary ideal, -prime ideal, quasi prime ideal, strongly irreducible ideal, and closed ideal, are studied. Also, the ideals of a principal ideal domain are classified into quasi prime ideals and -sequence quasi prime ideals.

Background: Pregnancy is a stressful state of increased inflammatory activity, and pregnancy – associated hormone changes can influence periodontal tissues, these inflammatory activity lead to production of inflammatory mediators. Interleukin 1 beta (IL-1β) is a potent pro-inflammatory cytokines that is consistently associated with periodontal diseases. This study was designed to determine the periodontal health status and detect the serum level of IL-1β in the healthy pregnant women at first, second and third trimester and compare it with healthy non pregnant women, and determine its correlation with different clinical periodontal parameters. M