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Genetic Polymorphisms at TNF-Alpha Receptors Associated some Autoimmune Diseases and Response of Anti-TNF Biologics: Review
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Some genetic factors are not only involved in some autoimmune diseases but also interfere with their treatment, Such as Crohn's disease (CD), Rheumatoid Arthritis (RA), ankylosing spondylitis (AS), and psoriasis (PS). Tumor Necrosis Factor (TNF) is a most important pro-inflammatory cytokine, which has been recognized as a main factor that participates in the pathogenesis and development of autoimmune disorders. Therefore, TNF could be a prospective target for treating these disorders, and many anti-TNF were developed to treat these disorders. Although the high efficacy of many anti-TNF biologic medications, the Patients' clinical responses to the autoimmune treatment showed significant heterogeneity. Two types of TNF receptor (TNFR); 1 and 2, it classified into two superfamilies; TNF-superfamily of ligands (TNFSF) (19 ligands) and TNF receptor superfamily (TNFRSF) (29 receptors). This review aims to provide an overview of the impact of genetic polymorphism on TNF alpha receptors on the response to anti-TNF biologics. Several single nucleotide polymorphisms (SNPs) recorded in the TNFRs gene on various immune system cells may affect the lower corresponding TNFRs gene expression. The present review summarized the studies that highlighted the role of heterogeneity in varying the response of patients. Many researchers indicated SNPs' effect on the response of autoimmune patients to treatment with anti-TNF biologic medications, while other studies did not find a correlation. In conclusion, TNF is involved in several diseases such as CD, RA, AS, and PS; there was a link between TNFRs polymorphism and non-responsiveness to anti-TNF-α medications.

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Publication Date
Mon Mar 01 2021
Journal Name
Journal Of Physics: Conference Series
Synthesis and characterization of some new thiazolidinone derivatives containing indole ring
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Many new heterocyclic compounds including 4-thiazolidinones containing indole with triazole units were described. The new Schiff bases [VII] a, b and [VIII] a, b synthesized by condensation acid hydrazides [II],[VI] with different (aromatic) aldehydes in absolute ethanol. The refluxing equimolar amounts of the Schiff bases ([VII] a, b,[VIII] a, b) with thioglycolic acid in benzene led to get thiazolidin-4-ones derivatives ([IX] a, b and [X] ad). Finally, the new derivatives [XI] ac run out via the reacted compound [IX] a with different n-alkyl bromide (methyl bromide, ethyl bromide, and butyl bromide)

Publication Date
Fri Dec 29 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Syntesis and Characterization of Complexes Anthranilic Acid With Some Metal Ions
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The  research includes attempts to prepare anthranil ic acid (C7H7N02) complexes  with some metals: [Pd (II), Fe(ll), and  Fe (Ill))  which have been characterized by using:

Thermal stability (melti ng point, d composition poit), molar conductivity, IR,   UV-visible   spectra,   elemental   analysis   (C-H-N)   and   magnetic properties.  The   general  formula   has   been  given for  the   prepared complexes:-

- M(C2H6N02)2 Where M= [Pd(ll), Fe(TI), Hg(ll)]

 

:.. M(C1H6N02)l Where  M= [Fe(llf)]

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Publication Date
Mon Mar 08 2021
Journal Name
Baghdad Science Journal
Effect of growth regulators on sex expression and some quantitatve properties
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This study was conducted in an orchard pomegranate's Department of Horticulture College of Agriculture, University of Baghdad for two seasons 1999-2000 on cultivars pomegranate Salimi and narrators seedless to study the effect spraying Nizant growth in sex ratio of flowers and recipes flowering and winning was selected 27 trees per class 15 years old planted

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Publication Date
Thu Apr 27 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Isolation and Identification of causative agents from some Iraqi Banknote currency
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   One hundred and twenty eight currency notes samples 250, 500, and 1000 Iraqi Dinars (ID) values were collected from students, markets, banks, and hospitals in Erbil city , Iraq. The results showed that all collected samples were contaminated with one or more bacteria and fungi  species representing 100% contamination and none from the new (control) notes. Seventeen bacterial species and twelve fungal species were isolated, which include Staphylococcus aureus (83.3%), Streptococcus pyogenes (83.3%), Pseudomonas species (83.3%), Aspergillus niger (83.3%), Klebsiella species (75%), Staphylococcus epidermidis (66.6%), and Escherichia coli (66.6%) being the most prevalent. The lower values of currency notes (250 ID and 500 I

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Publication Date
Wed Nov 24 2021
Journal Name
Iraqi Journal Of Science
Prevalence and Identification of Some Ocular Bacterial Infections in Baghdad City
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The study included 176 patients attended to Iben AL-Haithem hospital of ophthalmology in Baghdad city , at age of (14-77) years from the period from September 2016-April 2017, there were 138(78%) patients having a positive culture of ocular bacterial infections. Men were representing 41% while women 59%, the patients with bacterial ocular infection from Baghdad were55% while the internally displaced were 45% , the patients with ocular bacterial infections were representing 20% at mean age of 21.6±0.3y, 26% at 37.5±0.21y , 24% at53.5±0.23 y and 30% at69.5±0.10 y. The results showed 37% of the patients with ocular bacterial infections were having a history of diabetes mellitus and 44% with high blood pressure at mean age of 69.5±0.10

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Publication Date
Fri Oct 20 2023
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
New Metronidazole Derivative and Some of its Complexes with Antibiofilm Study
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Synthesis of a new ligand, namely [bis(2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl) hydrogen borate] (BIB), utilizing the reaction of metronidazole with boric acid in a (2:1) mole ratio The metal complexes were synthesized utilizing the reaction of (NiCl2.6H2O and CuCl2 .2H2O) with (BIB) ligand in a 2:1 (L:M) mole ratio. All synthesized compounds were characterized utilizing spectroscopic techniques such as infrared (FTIR), nuclear magnetic resonance of protons(1H NMR), ultra violet and visible radiation (UV-Vis), thermal analysis (TG), atomic absorption (A.A.S.), micro elemental analysis (C.H.N.S.), melting point (m.p.), magnetic susceptibility, molar conductivity, and chlor

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Publication Date
Wed Mar 16 2022
Journal Name
Journal Of Educational And Psychological Researches
Self-control of kindergarten teachers and its relationship to some variables
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The aim of the current research is to identify the self-control of kindergarten teachers as well as to identify the significance of the differences according to a variable (years of service, academic achievement, specialization). Its final paragraphs consist of (35) paragraphs, and its psychometric properties were verified and the tool was applied to a sample of (400) teachers chosen randomly from kindergarten teachers affiliated to the General Directorates of Education in Baghdad, Rusafa, and Karkh for the academic year 2019-2020

In light of the objectives of the current research, the following results were reached

  1. The current research sample is from kindergarten teachers with self-contro
  2. There are diffe

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Publication Date
Sun Apr 30 2023
Journal Name
Iraqi Journal Of Science
Detection of some heavy metals and bacterial contamination in canned vegetables
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In this paper, thirty six samples of canned vegetables were collected randomly from
different markets in Baghdad city from October 2013 till March 2014. The study
includes identifying the concentration of some heavy metals (lead, nickel, zinc and iron)
by flameless atomic absorption spectrophotometery. It was found that the higher
concentrations of heavy metals in canned vegetables, was lead 1.179 ppm in olive,
nickel 0.9078 ppm in olive, while zinc 10.143 ppm green peas and iron 90.601ppm in
white asparagus; but the lower concentrations represents with lead 0.0021 ppm in green
asparagus, nickel 0.0202 ppm in mushroom, while zinc 0.528 ppm in white asparagus
and iron 4.061 ppm in green peas. Canned food has been r

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Publication Date
Mon Apr 20 2020
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Analytical Study of Some Lightest Nuclei H, He, Li and Be
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     In the present study, the properties of the light elements, namely, H, He, Li, and Be, have been reviewed. Specifically, the nuclear decay of these nuclei has been reviewed. The mystery of the nuclear decay and potential is behind this work. The role of neutron has been investigated. The N/Z ratio has also been investigated in the study to relate the nuclear decay with the ratio. A new formula for nuclear potential has been suggested in the present study. This formula can describe the binding energy potential and the decayed particle energy depending on the N/Z ratio.

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Publication Date
Mon Mar 01 2021
Journal Name
Journal Of Physics: Conference Series
Synthesis and characterization of some new thiazolidinone derivatives containing indole ring
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Abstract<p>Many new heterocyclic compounds including 4-thiazolidinones containing indole with triazole units were described. The new Schiff bases [VII]<sub>a, b</sub> and [VIII]<sub>a,b</sub> synthesized by condensation acid hydrazides [II],[VI] with different (aromatic) aldehydes in absolute ethanol. The refluxing equimolar amounts of the Schiff bases ([VII]<sub>a,b</sub>, [VIII]<sub>a,b</sub>) with thioglycolic acid in benzene led to get thiazolidin-4-ones derivatives ([IX]<sub>a,b</sub> and [X]<sub>a-d</sub>). Finally, the new derivatives [XI]<sub>a-c</sub> run out via the reacted compound [IX]<sub>a</sub> with di</p> ... Show More
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