This study aimed to prepare a program (physical-nutritional) for women with polycystic ovary, as well as to identify the effect of this program on some body measurements and the incidence of polycystic ovarian syndrome in the research sample. A total of 12 women (aged 20-25 years) with Polycystic Ovary Syndrome (PCOS) participated in the randomized controlled trial design. They were divided equally into two groups (experimental and control group). The experimental group received the physical-nutritional program accompanying the treatment program, while the control group received only the instructions of the specialist doctor and the treatment program prepared by them. The two researchers applied their nutritional program over a period of two months and a day. As for the physical program, it was applied by 3 units per week, for a period of two months, which included a set of aerobic exercises. The assessments were done using the ultrasound assessment for radiographic examination and other body measurements such as BMI (Body Mass Index). The statistical analysis was carried out using the Statistical Package for Social Sciences (SPSS) version 25. The results of the current study showed that there were statistically significant differences between pre and post-test results of the experimental and control group for the study variables, in favor of the post-test (p < 0.05). Statistically significant differences were also found between the post-test score averages of the experimental and the control group, in favor of the experimental group (p < 0.05). In conclusion, diet helps to improve the work of vital organizations by targeting insulin resistance to reduce it, as it is one of the indicators that works to increase polycystic ovaries. About sports activities, they contribute to the regulation of the hormonal system and in this way reduce the incidence of PCOS.