Preferred Language
Articles
/
wRYOoogBVTCNdQwCF3lG
Deferasirox in thalassemia: a comparative study between an innovator drug and its copy among a sample of Iraqi patients
...Show More Authors
Background:

The health care industry is witnessing an increasing trend in the use of generic medicines because of their presumed low cost compared with innovator medicines. The aim of this study was to determine and compare the performance of the copy drug Osveral®and its innovator drug deferasirox (Exjade®).

Methods:

A prospective observational study including 223 patients receiving the branded medicine Exjade®and 101 patients receiving the copy Osveral®was carried out. Data were assessed for a 1-year period and included clinical symptoms, serum ferritin (SF), serum creatinine (SC), and alanine aminotransferase (ALT). Data were analyzed with SPSS version 22 software (SPSS, Chicago, IL, USA).

Results:

The median age of the sample was 8 years. There was no significant difference in gender distribution between the two groups ( p = 0.625). Nausea was the most frequently reported adverse effect followed by diarrhea and abdominal pain in both groups. Patients receiving Exjade®had a higher relative reduction of SF at the end of the study compared with the Osveral®group (19.9% versus 9.93%, p = 0.028). SC was found to be significantly higher in the Osveral®group than in the Exjade®group throughout the study period. The mean platelet count was higher in the Exjade®group. ALT was significantly higher among patients receiving Osveral®over the last three months of the study.

Conclusions:

Exjade®showed a better ability to reduce SF, with less liver toxicity, and better hemostasis profile. No congenital anomalies associated with short-term use of both drugs during pregnancy were observed or reported.

Scopus Clarivate Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Sun Aug 01 2021
Journal Name
International Journal Of Mechanical Engineering And Robotics Research
Adaptive Approximation-Based Feedback Linearization Control for a Nonlinear Smart Thin Plate
...Show More Authors

This paper proposes feedback linearization control (FBLC) based on function approximation technique (FAT) to regulate the vibrational motion of a smart thin plate considering the effect of axial stretching. The FBLC includes designing a nonlinear control law for the stabilization of the target dynamic system while the closedloop dynamics are linear with ensured stability. The objective of the FAT is to estimate the cubic nonlinear restoring force vector using the linear parameterization of weighting and orthogonal basis function matrices. Orthogonal Chebyshev polynomials are used as strong approximators for adaptive schemes. The proposed control architecture is applied to a thin plate with a large deflection that stimulates the axial loadin

... Show More
View Publication Preview PDF
Crossref (3)
Crossref
Publication Date
Fri May 18 2018
Journal Name
Thesis
The Arabian killifish (Aphanius dispar) as a novel model for mycophysiological studies.
...Show More Authors

Abstract Candida albicans is a commensal fungal pathogen that grows in yeast and hyphal forms in the human gut. C. albicans causes mucosal and cutaneous diseases that can result in significant mortality following systematic infections and it also exhibits drug resistance. Zebrafish have been an excellent model to investigate C. albicans infections because of their transparency and the availability of many transgenic lines. However, there is a limitation in using zebrafish as a model because the fish embryos cannot survive at 37°C therefore it is not suitable for studying Candida infections at physiological relevant human body temperature. In this thesis, the normal embryonic development of Arabian killifish (A. dispar) is investigated, rev

... Show More
Publication Date
Sat Jun 29 2013
Journal Name
Wireless Personal Communications
A Low Cost Route Optimization Scheme for Cluster-Based Proxy MIPv6 Protocol
...Show More Authors

View Publication
Scopus (3)
Crossref (3)
Scopus Clarivate Crossref
Publication Date
Tue Jan 01 2019
Journal Name
Iop
Water cut comparison for a really similar gridding system (line drive pattern)
...Show More Authors

Scopus
Publication Date
Thu Jun 01 2017
Journal Name
Chaos, Solitons & Fractals
A semi-analytical iterative method for solving nonlinear thin film flow problems
...Show More Authors

View Publication
Crossref (17)
Crossref
Publication Date
Mon Apr 02 2018
Journal Name
Al-nahrain Journal For Engineering Sciences (njes)
Output Feedback Adaptive Sliding Mode Control Design for a Plate Heat Exchanger
...Show More Authors

The heat exchanger is a device used to transfer heat energy between two fluids, hot and cold. In this work, an output feedback adaptive sliding mode controller is designed to control the temperature of the outlet cold water for plate heat exchanger. The measurement of the outlet cold temperature is the only information required. Hence, a sliding mode differentiator was designed to estimate the time derivative of outlet hot water temperature, which it is needed for constructing a sliding variable. The discontinuous gain value of the sliding mode controller is adapted according to a certain adaptation law. Two constraints which imposed on the volumetric flow rate of outlet cold (control input) were considered within the rules of the proposed

... Show More
Preview PDF
Publication Date
Fri Feb 05 2010
Journal Name
Etri Journal
MC-MIPOG: A Parallel t-Way Test Generation Strategy for Multicore Systems
...Show More Authors

View Publication
Scopus (43)
Crossref (27)
Scopus Clarivate Crossref
Publication Date
Sun Dec 31 2023
Journal Name
Sumer Journal For Pure Science
COVID-19Disease Diagnosis using Artificial Intelligence based on Gene Expression: A Review
...Show More Authors

Publication Date
Wed Jan 30 2019
Journal Name
Journal Of The College Of Education For Women
Attitude The King Ghazi a Problem the Border with Kuwait 1933-1939
...Show More Authors

King Ghazi (1933-1939) was of the Arabic characters that characterized national and
patriotic spirit and that faced the British policy in all its aspects.
King Ghazi distinguished as of Arab nationalist tendencies and called for the
liberalization of Arab lands which were under the rule of the Ottoman Empire. He called for
reunification under the one Arab country, Hence came the King invitations to liberate Kuwait
from the British protectorate and consolidated with Iraq.
King Ghazi established a private radio station in the royal palace (AL zzaahoor) palace
and provided special programs to return of Kuwait to Iraq, this radio station was The
prominent role in the revitalization of the Kuwaiti National Movement, an

... Show More
View Publication Preview PDF
Publication Date
Fri May 30 2014
Journal Name
Applied Surface Science
Liquid Phase - Pulsed Laser Ablation: A route to fabricate different carbon nanostructures
...Show More Authors

Scopus (54)
Scopus