Preferred Language
Articles
/
wRYOoogBVTCNdQwCF3lG
Deferasirox in thalassemia: a comparative study between an innovator drug and its copy among a sample of Iraqi patients
...Show More Authors
Background:

The health care industry is witnessing an increasing trend in the use of generic medicines because of their presumed low cost compared with innovator medicines. The aim of this study was to determine and compare the performance of the copy drug Osveral®and its innovator drug deferasirox (Exjade®).

Methods:

A prospective observational study including 223 patients receiving the branded medicine Exjade®and 101 patients receiving the copy Osveral®was carried out. Data were assessed for a 1-year period and included clinical symptoms, serum ferritin (SF), serum creatinine (SC), and alanine aminotransferase (ALT). Data were analyzed with SPSS version 22 software (SPSS, Chicago, IL, USA).

Results:

The median age of the sample was 8 years. There was no significant difference in gender distribution between the two groups ( p = 0.625). Nausea was the most frequently reported adverse effect followed by diarrhea and abdominal pain in both groups. Patients receiving Exjade®had a higher relative reduction of SF at the end of the study compared with the Osveral®group (19.9% versus 9.93%, p = 0.028). SC was found to be significantly higher in the Osveral®group than in the Exjade®group throughout the study period. The mean platelet count was higher in the Exjade®group. ALT was significantly higher among patients receiving Osveral®over the last three months of the study.

Conclusions:

Exjade®showed a better ability to reduce SF, with less liver toxicity, and better hemostasis profile. No congenital anomalies associated with short-term use of both drugs during pregnancy were observed or reported.

Scopus Clarivate Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Thu Nov 01 2018
Journal Name
Iraqi National Journal Of Nursing Specialties
Testing Bromocriptine Dose Necessary For Suppression of Lactation in Rats: Morphological Study
...Show More Authors

Abstract: Objectives: The lowest dose of bromocriptine, necessary for suppression of lactation in rats, was estimated in this investigation. Methodology: Fifty healthy lactating rats were treated with different doses of bromocriptine. Cessation of lactation was assessed clinically and histologically. Results: Revealed that the lowest dose capable of lactation suppression is 4 mg bromocriptine / kg body wt. / day. It is very important to know the exact dose, which can suppress lactation in rats because these laboratory animals are commonly employed in experiments concerning this topic. Key words: Bromoci

... Show More
View Publication Preview PDF
Publication Date
Sun Sep 30 2007
Journal Name
Iraqi Journal Of Chemical And Petroleum Engineering
Study of Catalysts Deactivation in Isomerization Process to Produce High Octane Gasoline
...Show More Authors

In this study  the isomerization of desulfuerized light Iraqi petroleum naphtha (Al-Dura Refinery) with boiling point range of 37 to 124 °C , 80.5 API specific gravity and 68.2 octane number has been investigated. Two types of catalysts were prepared (Pt/HX and Pt/SrX) by impregnation of 0.8 wt% Pt on l 3X-zeolite. The catalyst activity and selectivity toward isomerization, and catalyst deactivation were investigated.

The isomerization unit consisted of a vertical tubular stainless steel reactor of 2 cm internal diameter, 3 cm external diameter and 68 cm height. The operating pressure was atmospheric for all experimental runs.  The liquid flow of light­naphtha was 0.4 Uh, and the catalyst weight was 50 gm, H/

... Show More
View Publication Preview PDF
Publication Date
Fri Apr 01 2016
Journal Name
Journal Of Engineering
Numerical Study of Heat Transfer Enhancement in Heat Exchanger Using AL2O3 Nanofluids
...Show More Authors

In this study, the flow and heat transfer characteristics of Al2O3-water nanofluids for a range of the Reynolds number of 3000, 4500, 6000 and 7500 with a range of volume concentration of 1%, 2%, 3% and 4% are studied numerically. The test rig consists of cold liquid loop, hot liquid loop and the test section which is counter flow double pipe heat exchanger with 1m length. The inner tube is made of smooth copper with diameter of 15mm. The outer tube is made of smooth copper with diameter of 50mm. The hot liquid flows through the outer tube and the cold liquid (or nanofluid) flow through the inner tube. The boundary condition of this study is thermally insulated the outer wall with uniform velocity a

... Show More
View Publication Preview PDF
Publication Date
Fri Feb 23 2018
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Study the Influence of Captopril on Bone Metabolism in Elderly Hypertensive Women
...Show More Authors

Widespread use of antihypertensive agents in clinical practice necessitates the knowledge of their pleiotropic effects. At the present time there are no sufficient evidences of positive effect of these medications on bone coming from randomized controlled trials; knowledge of additional effects of those drugs on the bone metabolism will allow doctors to choose optimal treatment of hypertension, taking into account the state of bone tissue. At the same time it will also allow to prevent osteoporosis in patients having osteoporosis risk factors or initial signs of bone loss.

Ten elderly hypertensive women age > 60 years old (64.2±3.6) treated with captopril for a 5-6 years ago while they attending Al Yarmouk Teaching Hospital i

... Show More
View Publication Preview PDF
Crossref
Publication Date
Thu Oct 20 2022
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
The Histological Study of the Ileum in the Caucasian Squirrel Sciurus anomalus
...Show More Authors

The current study was designed to identify the histological composition of the ileum in the Caucasian squirrel Sciurus anomalus. Ten adult squirrels were used for the present study. Animals were anesthetized, anatomized, fixed the study specimens in 10% formalin solution, and conducted a series of histological staining techniques. The ileum consists of four main tunicae represented by mucosa, submucosa, muscularis, and serosa. The tunica mucosa consists of three secondary layers: the epithelial lining layer, lamina propria, and muscularis mucosa. The epithelial lining comprises simple columnar epithelial tissue composed of columnar cells and goblet cells. The lamina propria contains simple straight tubular glands called the int

... Show More
View Publication Preview PDF
Crossref
Publication Date
Thu Mar 09 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Histological Study of The Cerebellum In Adult Quail Coturnix coturnix (Linnaeus, 1858)
...Show More Authors

 A histological study was conducted to examine the structure of Cerebellum in Coturnix coturnix (Linnaeus). The results showed that the cerebellum is a portion of the Rhombencephalon and Metencephalon lying behind the cerebrum, the surface of the cerebellum contains deep folds and appears spherical in its shape. It represented the dorsal side of metencephalon and surrounded the roof of IV ventricle.          The cerebellum consists of three parts spino cerebellum, cerebro cerebelluum and vestibulo cerebellum; and three lobes anterior lobe, posterior lobe and flocculonodular lobe. The corpus cerebellum (Vermis) consists of nine folds called cerebellar-folia (IX-I) and separated from each other by sulci. &nbsp

... Show More
View Publication Preview PDF
Publication Date
Sat May 01 2021
Journal Name
Journal Of Physics: Conference Series
Anatomical study of Solanum nigrum L. from Solanaceae family growing in Iraq
...Show More Authors
Abstract<p>The most important features that we have reached through this study, are shown the cross-section of root were in the secondary growth stage and the epidermis of leaf were studded by stomata complex, the type of it was anomocytic that’s mean no have subsidiary cells around the guard cells, the mesophyll bifacial also the midrib region of leaf like the pear and the vascular bundle located in the center crescent in shape. The cross-sections of petiole ovate shape with two ears in the lateral side and the vascular bundles crescent in shape. The cross-section of fruits circular component of three-layer the outer layer pericarp, mesocarp, and the endocarp, surrounding the ovary or the see</p> ... Show More
View Publication
Scopus (4)
Scopus Crossref
Publication Date
Sun Jul 09 2023
Journal Name
Journal Of Engineering
Study the Application of Ultrasonic Technology for Phenol Removal in Petroleum Industry
...Show More Authors

In this study, the sonochemical degradation of phenol in water was investigated using two types of ultrasonic wave generators; 20 kHz ultrasonic processor and 40 kHz ultrasonic cleaner bath. Mineralization rates were determined as a function of phenol concentration, contact time, pH, power density, and type of ultrasonic generator. Results revealed that sonochemical degradation of the phenol conversion was enhanced at increased applied power densities and acidic conditions. At 10 mg/L initial concentration of phenol, pH 7, and applied power density of 3000 W/L, the maximum removal efficiency of phenol was 93% using ultrasonic processor at 2h contact time. Whereby, it was 87% using and ultrasonic cleaner bath at 16h contact time and 150 W

... Show More
View Publication Preview PDF
Crossref
Publication Date
Sun Apr 01 2018
Journal Name
Journal Of Educational And Psychological Researches
The Experience of Disabled Female Students at Academic Study in Saudi Universities
...Show More Authors

The current study aims to examine the experience of female students with disabilities who studying in university in kingdom of Saudi Arabia. To this end, the researcher used semi-structured interview as an instrument to collect the study data which regards as one of the descriptive approach tools. The sample comprised (12) disabled-female students from multidiscipline within both college of arts and college of education. To analyze the collected data, the author utilized a thematic analysis method following six steps as stated by (Braun and Clark, 2006). The findings revealed that disabled students have a high self-confidence which push them forward to take part in activities that hold on campus. Besides, significant variation were shown

... Show More
View Publication Preview PDF
Publication Date
Sun Dec 31 2017
Journal Name
College Of Islamic Sciences
The role of the media in promoting tolerant religious values: intellectual study
...Show More Authors

Research summary

Informing means informing and informing, which is conveying information to someone and confirming his narration with it. Accordingly, information is its main content..and it has multiple means, including visual, audio and read, and it has become the dominant role in the process of socialization, and much of what we hear, read, or watch in the media is not devoid of a goal, and expresses that scientifically as “charged with values” ( Value Loaded)..Values that are: the set of beliefs that the individual holds towards things, meanings, and various aspects of activity, which direct his desires and attitudes towards them, and determine for him acceptable and unacceptable behavior, right and wrong, and all of this

... Show More
View Publication Preview PDF