A smart home’s safety is a very urgent question due to several causes. This chapter analyzes current directions of smart house system safety technologies in use nowadays. Current studies are dedicated to the integration of Internet of Things (IoT) into smart home systems; critical situations that may arise; and specifications of sensors in the smart home system. The huge number of connected devices and the capacity embedded within these devices to direct demand resources make deliberate attacks on them and/or inadvertent downfall events such as abrupt bad interactions between connected devices, mechanical failure of devices, and unsuccessful communication may lead to IoT-based systems entering unreliable and threatening physical states. We review current trends in security-enabled safety monitoring frameworks for IoT-based smart homes. We demonstrate the use of various techniques in utilizing system analysis during design to develop a monitoring model that can be executed, providing run-time safety assurance for a system. This is achieved through collecting and analysis of operational data and evidence to assess the safety status of the system. Subsequently, appropriate actions are taken, and the safety status is communicated securely to system users, along with recommended actions to reduce the risk of the system entering an unsafe state.