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Impacts of the alcoholic extract and essential oil of Thymus vulgaris L. Against the causative agent of acne formation (Staphylococcus aureus)

Medicinal plant life have performed an integral role in the development of human lifestyle being used as resources for the manufacturing of contemporary medicines, antibiotics. Microorganisms are responsible for many issues in industry and remedy because of biofilm formation. This study aimed to take a look at the results of Thymus vulgaris alcoholic extract on Staphylococcus aureus the causative marketers of acne in human particularly the women. The extract was acquired mixing 25 g of Thyme powder with 350 ml of 80% ethanol for 6 hours at 40°. Antimicrobial activities of the plant extract and integral oil towards the S. aureus were decided using the agar diffusion technique. The consequences proven that special concentrations of alcoholic extract (5, 10, 15 mg/ml) prompted accelerated diameters of bacterial boom inhibition zones (20, 40, 27.7, and 30 mm respectively) as compared to the control (20mm). Increased diameters of inhibition zones (20.6, 32.33, 22 mm) have been additionally determined in response to remedy with extraordinary concentrations of plants crucial oil (0.5, 1.5, and 2 p.c respectively) in evaluation to the manage (0.0%). The inhibitory consequences of the extracts and vital oil had been directly correlated to their concentration. Two an fascinating end result bought in this study that alcoholic extract showed superior antibacterial exercise against the examined gram-positive bacterium than thyme oil. Two According to the workable of T. Vulgaris extracts to inhibit the tested bacteria, it can be suggested that these extracts can be applied as antimicrobial retailers towards the effects of pathogenic bacteria specifically acne formation.

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Publication Date
Thu Dec 15 2022
Journal Name
Journal Of Baghdad College Of Dentistry
Experimental In vitro Study to Assess the Antibacte-rial Activity of Thymus vulgaris Oil on Streptococ-cus Sanguinis

Background: The Streptococcus genus are the predominant bacteria in the mouth and the Streptococcus sanguinis is one of them which performing a primary function for expansion of dental biofilm. Gingival and periodontal disorders are caused by dental biofilm, today, there is a necessity to discover naturally presenting antibacterial compounds from herbs with less side effects as a substitutive to the commonly handled chlorohexidine. Thus, the purpose of this study was to assess the antibacterial activity of thymus vulgaris oil on Streptococcus sanguinis bacteria In vitro. Materials and Methods: Human supragingival plaque samples were taken from 10 subjects, then morphological and microscopical examination, bioch

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Publication Date
Tue Mar 14 2023
Journal Name
Iraqi Journal Of Science
The Biological Effect of Rosmarinus officinelis L. Essential Oil on Biofilm Formation and Some Fimbrial Genes (fimH-1 and mrkD) of Klebseilla pneumoniae

Klebseilla pneumoniae possesses many virulence factors and survival strategies to persist and overcome host defenses; one of these strategies is biofilm formation. Therefore, the aims of this study was to determine the antibacterial and antibiofilm effect of Rosmarinus officinelis L. essential oil (EO) and its effect on the genes encoding of fimbrial adhesions. The antimicrobial activity was investigated by MIC. The ability to form biofilm as well as inhibition of initial cell attachment and biofilm formation was performed. PCR was carried out to detect fimH-1 and mrkD genes of type 1 and type 3 fimbrial adhesions at different time of incubation. The study revealed that MIC value of EO was 104 μg/ml on 24 (83%) of isolates, 93% of them

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Publication Date
Wed Jan 01 2020
Journal Name
Biochemical And Cellular Archives
EFFECT OF CHALCONE ON THE FORMATION OF BIOFILMS AND EXPRESSION OF VIRULENCE GENES IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS

MRSA is one of the major pathogens in hospitals and the community, which have the ability to produce biofilm as a virulence factor, the impact of chalcone on biofilm formation, the synergism effect of chalcone and antibiotic in both in vitro and in vivo experiments, the gene expression of virulence genes (srtA, fnbA, fnbB) before and after treatment of it on MRSA biofilm cells in vitro, all these were the prime aims of this study. Chalcone at MBIC (20 μg/ml), significantly reduced the biofilm formation to 21.45% and at sub MBIC (15 μg/ml) to 36.58 %. While, Chalcone at MIC(5 μg/ml) reduced MRSA planktonic cells to 49.61%. Susceptibility of MRSA isolates against eight antibiotics showed that all isolates were sensitive to vancomycin and n

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Publication Date
Wed Oct 31 2018
Journal Name
Iraqi Journal Of Science
The Biological Activity of Eucalyptus rostrata Leaves Extraction against E.coli and Staphylococcus aureus isolated from Iraqi Patients

The inhibitory effect of Eucalyptus rostrata leaves extraction was investigated on multiple-antibiotic-resistant pathogenic bacteria (E.coli and S. aureus), isolated from Iraqi patients. The minimum inhibitory concentrations in a final concentration of 10 mg/ml. Tow fold dilutions was done from (12.5- 100) mg/ ml to examine the antibacterial effect of different concentrations of the plant extract on both bacteria. The study results revealed that Eucalyptus rostrata extract has a potential inhibitory effect on both gram negative and gram positive species. The current study supports the traditional approach of using Eucalyptus rostrata leaves extraction in treatment trails against bacterial infections.

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Publication Date
Thu Oct 31 2019
Journal Name
Al-kindy College Medical Journal
Assessment of efficacy and safety of dapsone gel 5% in the treatment of acne vulgaris

ABSTRACTBackground : Acne vulgaris is a
common skin disease, affecting more than 85% of
adolescents and often continuing into adulthood.
People between 11 and 30 years of age and up to
5% of older adults. For most patients acne remains
a nuisance with occasional flares of unsightly
comedones, pustules and nodules. For other less
fortunate persons, the sever inflammatory response
to Propionibacterium acnes (P.acnes) results in
permanent
Methods: Disfiguring scars. (1, 2) Stigmata of sever
acne cane lead to social ostracism, withdrawal
from society and severe psychologic
depression (1-4).
Result Pathogenesis of acne Traditionally, acne
has been thought of as a multifactorial disease of
the fo

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Publication Date
Tue Dec 26 2023
Journal Name
Proceedings Of Researchfora International Conference, Dubai, Uae
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Publication Date
Sun Feb 21 2021
Journal Name
Iraqi Journal Of Science
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Publication Date
Fri Feb 26 2021
Journal Name
Iraqi Journal Of Science
The Antimicrobial Effects of Alcoholic Leaves Extract of Salvia Officinalis Against Multidrug Resistant Pseudomonas Aeruginosa

Two isolates of Pseudomonas aeruginosa were isolated from patients with Urinary Tract Infection (UTI). The aim of this study was to determine the antimicrobial effect of alcoholic leaves extract of Salvia officinalis on Multidrug resistant (MDR) P. aeruginosa. Using the well diffusion test, the alcoholic leaves extract at 100mg/ml and 200 mg /ml was shown to possess antimicrobial activity against the tested microorganism. The inhibition zones of S. officinalis at 200 mg/ml, and 100 mg/ml of the extract showed diameters of 23mm and 20mm, respectively. But the diameters of the inhibition zones caused by treatment with the antibiotics Ciprofloxacin, Ticarcillin + Clavulanic acid, and Cefotaxime w

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Publication Date
Sun Apr 30 2023
Journal Name
Iraqi Journal Of Science
Comparison of the inhibitory effect of the alcoholic extract of pomegranate peel and antibiotics against some intestinal bacterial isolates

This research included isolation of 18 bacterial isolates from children stool with diarrhea and acute bloody water and under the age of five, if possible get a 9 isolates of the bacterium Escherichia coli and 5 isolates of the bacterium Salmonella typhimurium and 4 isolation of the bacterium Shigella flexneri, subjected all of these isolates tests AGRO and microscopic and biochemical and diagnosed using Vitek2 system. Tested the effectiveness of inhibitory extract alcohol to peel pomegranate Punica granatum L. in the growth of isolates bacterial intestinal and using the diffusion method in drilling Well diffusion as well as determine the focus damper Near Minimum inhibitory concentration MIC and focus killer Near Minimal bactericidal con

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Publication Date
Sat Dec 31 2022
Journal Name
Iraqi Journal Of Market Research And Consumer Protection
EFFECT OF Artemisia vulgaris L. AQUEOUS EXTRACT ON SOME GERMINATION PROPERTIES AND SEEDLING GROWTH OF LINSEED : EFFECT OF Artemisia vulgaris L. AQUEOUS EXTRACT ON SOME GERMINATION PROPERTIES AND SEEDLING GROWTH OF LINSEED

ABSTRACT

            A laboratory experiment was carried out during winter season of 2021 in the Seed Technology Laboratory- College of Agricultural Engineering Sciences/ University of Baghdad, to find out the allopathic effects of aerobic and terrestrial aqueous extracts of Artemisia vulgaris L. on the seed germination and seedling growth of linseed. A factorial experiment according to a completely randomized design (CRD)at three replicates was used; the first factor in clouded type of aqueous extract for two plant parts which were aerobic (stems and leaves) and terrestrial (root and rhizomes), while the second factor included five concentrations

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