The current study included the collection of 175 samples (blood-urea) of patients suffering from rheumatism, collected from Baghdad Teaching Hospital (Educational Laboratory), Al-Kindy Teaching Hospital, Al-Imamian Al-Kadhimya in Medical City in Baghdad at different duration between 2016/10/1-2017/2/1. The bacterial growth results showed that 80% of urea samples positive for bacterial culture, while the rate of samples did not show any bacterial grow this 20%. The isolation subjugates to morphological, microscopically and biochemical tests, as also diagnosis by Api system. The most frequent bacterial pathogenic is E. coli which appeared highly rate (41.97)% followed by E. cloacae (21.25)%, P. aeruginosa (12.5)%, Salmonella (10)% and the proportion of K. pneumonia (7.5)%, while S. marcescens showed (6.25)%. When the measurement of the concentration of liver enzymes Glutamic Oxalate Transaminase (GOT), Glutamic Pyruvate Transaminase (GPT), Alkaline phosphates’(ALP), the results showed a significant degreaseP≤ 0.05 in the level of enzyme GPT in patients serum which reachto16. 94±0.84 mg/ml, while its level in the healthy serum was 0.68±6.78 mg/ml. ALP enzyme results showed non-significant high atP≤ 0.05 in the level of patients serum with rheumatoid arthritis, as it reached the level in the serum 2.46±134.42 mg/ml, while the level in the healthy serum was 0.50±4.11 mg/ml. The enzyme GOT showed on-significant high at P≤ 0.05 in the level of patients serum as it reached the level in the serum 0.88±21.51 mg/ml, while the level in the healthy serum was 0.50±4.11 mg/ml.