Cerebellum (cb) is the most important and sensitive part of the central nervous system (CNS) after cerebrum. The exposure to any infection during embryogenesis produces abnormalities in the cerebellum function and morphology that effect on behavioral of offspring later. In the present study we used 30 mature female pregnant albino rats divided in to three groups, each group contain 10 females: G1 was considered the control group received D.W only, while G2 group treated orally with (2mg/kg /day) suspension of silver nanoparticles (AgNPs) and G3 group treated orally with (20mg/kg/day) AgNPs. The embryos retrieved in different embryonic days from ED12 to ED21. In this study morphometric analysis was measured in the developing albino rats cerebellum after maternal exposure to two concentrations of AgNPs from preimplantation period until delivery . we measured the morphometric parameters (area, perimeter, anterior-posterior diameter APD and transverse diameter TD) of the selected embryonic days; ED12,ED15,ED18, and ED21 and retrieved the embryos from these days. The morphometric results in the control group(G1) showed that increased significantly (P≤ 0.05) in the area of the developing cerebellum from ED12 until reach the optimal level in the end of gestation at ED21 (14.0815mm2 to 18.969 mm2 respectively), perimeter (9.804 mm2 to 16.267 mm2) and TD (52.6308μm to 431.6 μm),while the APD value was increased significantly (P≤ 0.05) at ED12 and ED15 only (367.0041 μm, 454.011 μm )respectively but the orientation growth of the cerebellum decreased significantly (P≤ 0.05) at the later stage of the development at ED18 and ED21(364.48 μm, 225μm) respectively. In the present research both concentrations of the AgNPs (2mg and 20 mg/kg/ B.Wt) showed changes in the dimensions of the developing cerebellum cortex according to the studied morphometric parameters; in the 2 mg/kg/ B.Wt, the area of the developing cerebellum cortex was increased significantly (P≤0.05) from ED12 (47.437mm 2) and reached to maximum growth at ED18 (130.220 mm2), while it is growth inhibited at ED21( 68.909 mm2) compared to control group, the values of the developing cerebellum cortex perimeter increased significantly (P≤0.05) from ED12 until ED15 (0.964 mm 2, 2.548 mm 2) respectively compared to control group; TD values of the developing cerebellum cortex increased significantly (P≤0.05) from ED12 until ED15 also (259.341 μm,436.203 μm) respectively compared to control group. While the APD of the developing cerebellum cortex was decreased significantly (P≤0.05) during late development of the cortex at ED18 and ED21(330.415 μm, 131.5 μm) respectively as in the control group. In G3 group which treated with 20mg/kg/ B.Wt concentration of AgNPs, the similar results of area were showed as in the lower concentration, area of the developing cortex increased significantly (P≤0.05) from ED12(80.11mm 2) and reached to maximum growth at ED18(140.56 mm2) and lower after that. the values of the developing cerebellum cortex perimeter increased significantly (P≤0.05) from ED12 until ED15 (0.256 mm2, 0.543 mm2) respectively compared to control group; while in the APD and TD values the effect of the higher concentration of the AgNPs was more effect on these dimensions; APD values decreased significantly (P≤0.05) at ED15 (360.48 μm ) and not reach to the complete growth, also in TD values decreased at ED15 (400.5744 μm) and do not reach to maximum growth at end embryonic development compared to the embryonic development timing in the control group.
The last decade has seen a variety of modifications of glass-ionomer cements (GICs), such as inclusion of bioactive glass particles and dispensing systems. Hence, the aim was to systematically evaluate effect of mixing modes and presence of reactive glass additives on the physical properties of several GICs.
The physical properties of eight commercial restorative GICs; Fuji IX GP Extra (C&H), KetacTM Fill Plus Applicap (C&H), Fuji II LC (C&H), Glass Carbomer Ce
Variation orders are an on-going phenomenon in construction and industry projects worldwide, particularly in the province of Sulaimani, where the project's damage from cost and schedule overrun because of variation orders. However, the effect on project costs and time overrun of variation order has yet to be identified. This study evaluates the impact of variation orders on the cost and time off in the Sulaimani governorate. Two hundred twenty-eight projects from various construction sectors built between 2007-2012 were adopted to calculate the contract cost and schedule overruns due to variation orders. Data analysis was applied in the study were descriptive statistics. One-way ANOVA was also applied to determine w
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The fundamental turning point in American policy towards the Iran was the success of the Islamic revolution in Iran 1979 . Since than U S policy has been hostile to Iran . After the events 11 September 2001 , there was an American idea of dialogue with some countries opposed to US policy , including Iran . In 2004 the United States launched the Greater Middle East project , which contain a range of political , economic and cultural proposals for the region , all of which were in the interest of the United States and ( Israel ) , which Iran opposed . The failure of U S projects in region prompted the United States to agree with Iran on the nuclear file . On 8 May 2018 U S President Donald Trump of
... Show MoreThe foreign policy of china is considered an important subject generally, in addition its very significant towards the Middle East specifically. It is the most valued topic, that needs deep academic investigations in order to identify the important factors causes and its consequences, this kind of research provides a proper understanding to the researchers and politicians, it will prove the reasons for China's with the impact to the region, the rivalry with the United States in the coming years
the power of the federal supreme court to stop the implementation of the law
The importance of operational risks increases with the increase in technological development, the development of banking operations, the extent of banking compliance, and the attempt of many banks to achieve quality in banking services. And the extent of the position occupied by Iraqi banks for banking compliance and reducing operational risks. The Basel Committee (2) paid its attention to operational risks and the interest of international banks to follow policies that work to ensure banking compliance and cover operational risks, because of its role in reducing losses due to increased costs and achieving an increase in profits. Realizing and working to confront the best possible and traditional methods, that some risks Operational problem
... Show MoreFeed Forward Back Propagation artificial neural network (ANN) model utilizing the MATLAB Neural Network Toolbox is designed for the prediction of surface roughness of Duplex Stainless Steel during orthogonal turning with uncoated carbide insert tool. Turning experiments were performed at various process conditions (feed rate, cutting speed, and cutting depth). Utilizing the Taguchi experimental design method, an optimum ANN architecture with the Levenberg-Marquardt training algorithm was obtained. Parametric research was performed with the optimized ANN architecture to report the impact of every turning parameter on the roughness of the surface. The results suggested that machining at a cutting speed of 355 rpm with a feed rate of 0.07 m
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