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The effect of a psychological scare on the dynamics of the tumor-immune interaction with optimal control strategy

Contracting cancer typically induces a state of terror among the individuals who are affected. Exploring how chemotherapy and anxiety work together to affect the speed at which cancer cells multiply and the immune system’s response model is necessary to come up with ways to stop the spread of cancer. This paper proposes a mathematical model to investigate the impact of psychological scare and chemotherapy on the interaction of cancer and immunity. The proposed model is accurately described. The focus of the model’s dynamic analysis is to identify the potential equilibrium locations. According to the analysis, it is possible to establish three equilibrium positions. The stability analysis reveals that all equilibrium points consistently exhibit stability under the defined conditions. The bifurcations occurring at the equilibrium sites are derived. Specifically, we obtained transcritical, pitchfork, and saddle-node bifurcation. Numerical simulations are employed to validate the theoretical study and ascertain the minimum therapy dosage necessary for eradicating cancer in the presence of psychological distress, thereby mitigating harm to patients. Fear could be a significant contributor to the spread of tumors and weakness of immune functionality.

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Publication Date
Sat Jan 01 2022
Journal Name
Communications In Mathematical Biology And Neuroscience
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Publication Date
Tue Jan 01 2013
Journal Name
العلوم التربوية والنفسية
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Publication Date
Mon Jul 20 2020
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
The Continuous Classical Optimal Control Problems for Triple Nonlinear Elliptic Boundary Value Problem

     In this research, our aim is to study the optimal control problem (OCP) for triple nonlinear elliptic boundary value problem (TNLEBVP). The Mint-Browder theorem is used to prove the existence and uniqueness theorem of the solution of the state vector for fixed control vector. The existence theorem for the triple continuous classical optimal control vector (TCCOCV) related to the TNLEBVP is also proved. After studying the existence of a unique solution for the triple adjoint equations (TAEqs) related to the triple of the state equations, we derive The Fréchet derivative (FD) of the cost function using Hamiltonian function. Then the theorems of necessity conditions and the sufficient condition for optimality of

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Publication Date
Mon Jan 20 2020
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
The Continuous Classical Optimal Control governing by Triple Linear Parabolic Boundary Value Problem

This paper deals with the continuous classical optimal control problem for triple partial differential equations of parabolic type with initial and boundary conditions; the Galerkin method is used to prove the existence and uniqueness theorem of the state vector solution for given continuous classical control vector. The proof of the existence theorem of a continuous classical optimal control vector associated with the triple linear partial differential equations of parabolic type is given. The derivation of the Fréchet derivative for the cost function is obtained. At the end, the theorem of the necessary conditions for optimality of this problem is stated and is proved.

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Publication Date
Sat Dec 30 2023
Journal Name
Iraqi Journal Of Science
On The Dynamics of Discrete-Time Prey-Predator System with Ratio-Dependent Functional Response

In this paper, a discrete- time ratio-dependent prey- predator model is proposed and analyzed. All possible fixed points have been obtained. The local stability conditions for these fixed points have been established. The global stability of the proposed system is investigated numerically. Bifurcation diagrams as a function of growth rate of the prey species are drawn. It is observed that the proposed system has rich dynamics including chaos.

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Publication Date
Sat Feb 27 2021
Journal Name
Iraqi Journal Of Science
The Dynamics of a Food Web System: Role of a Prey Refuge Depending on Both Species

This paper aims to study the role of a prey refuge that depends on both prey and predator species on the dynamics of a food web model. It is assumed that the food transfer among the web levels occurs according to Lotka-Volterra functional response. The solution properties, such as existence, uniqueness, and uniform boundedness, are discussed. The local, as well as the global, stabilities of the solution of the system are investigated. The persistence of the system is studied with the assistance of average Lyapunov function. The local bifurcation conditions that may occur near the equilibrium points are established. Finally, numerical simulation is used to confirm our obtained results. It is observed that the system has only one type of a

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Publication Date
Sat Jul 31 2021
Journal Name
Iraqi Journal Of Science
Studying the Chaotic Dynamics Using Rossler-Chua Systems Combined with A Semiconductor Laser

     In this paper, two different chaotic dynamic systems are coupled using a semiconductor laser to produce a new chaotic system. These two chaotic systems are Rossler and Chua systems. X-dynamic of Rossler system was coupled optically using optical fiber as a carrier of signal with x, y, and z-dynamics of Chua system. The results were analyzed and the behavior of Chua system was found to be changing in time series which, in turn, changed the attractor. The Chua attractor was converted from double scroll to single scroll. The results obtained from connecting two different systems in chaotic behavior showed a remarkable increase in the bandwidth of Chua system. This increase in bandwidth opens up a wide field for many

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Publication Date
Mon Aug 20 2018
Journal Name
Physical Review E
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Publication Date
Tue Jan 02 2018
Journal Name
Journal Of Educational And Psychological Researches
The effect of 5555 strategy on reading comprehension among 4th preparatory students

The effect of 5555 strategy on reading comprehension among 4th preparatory students Assist. Prof. Dr. Hassan Khilbas Hammadi College of Education Ibn Rushd – The University of Baghdad Assistant Lecturer. Waleed Khaled Talib Directorate – General For Education Province Of AL - Anbar The purpose of study is to identify the effect of 5555 strategy on reading comprehension among 4th preparatory students. To do this, null hypothesis was postulated. The author hypothesize that there is no a statistically significant difference at (0.05) level between experimental group's scores who study reading comprehension subject following the 5555 strategy and control group's scores who study the same subject following the traditional method in readin

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Publication Date
Sun Jul 02 2006
Journal Name
Journal Of The Faculty Of Medicine Baghdad
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