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The Correlation between Insulin Resistance and Urotensin II in Patients with Gestational Diabetes Mellitus

Gestational diabetes mellitus is glucose intolerance of varying degree with onset or first detection duringpregnancy,it can causelong and short term morbidities in both the mother and the child, such as shoulder dystocia,preeclampsia, and high blood pressure. The most powerful endogenous vasoconstrictor peptide, urotensin II, andits receptor are involved in the etiology of gestational diabetes mellitus.Aim of the study: The study’s goal was to see if there is a link between Urotensin II levels and insulin resistancein pregnant women with gestational diabetes.Patients and method: A case-control study that was conducted in obstetrics and gynecology department atBaghdad Teaching hospital from the first of January 2019 to the end of December 2019. A sample of 80 pregnantwomen participated in the study fulfilling inclusion criteria. 40 of them diagnosed with gestational diabetesmellitus by (2 hours 75 gm. Oral glucose tolerance test) and 40 women as control group.Results: The mean age of the gestational diabetes mellitus group was 29.8±6.9 years and control was 29.7±6.6years with no significant differences. The study showed highly significant increase infasting Insulin, fasting bloodglucose, Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), of the GDM group than that in thegroup without disease. Significant difference was found regarding high-sensitivity C-reactive protein hs-CRP(p=0.004). The level of Urotensin II in subjects with gestational diabetes was (109±33.22) highly increased than thatin healthy subjects (78±22.6). There is a positive correlation between circulating Urotensin II levels with fastinginsulin, and HOMA-IR. While negative correlation found with fasting blood glucose. Conclusion: The level of UII was found to be raised in gestational diabetes pregnant women

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Publication Date
Sun Apr 04 2010
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Status of Some Minerals in Patients with Polycythemia using Colorimetric Method

Background: Polycythemia (or polycythaemia or erythrocytosis) is a condition in which there is a net increase in the total number of blood cells, primarily red blood cells, in the body. The overproduction of red blood cells may be due to a primary process in the bone marrow (a so-called myeloproliferative  syndrome), or it may be a reaction to chronically low oxygen levels or, rarely, a malignancy. Minerals are the building blocks of our bodies. They are required for body structure, fluid balance, protein structures and to produce hormones. They are the key for the health of every body system and function. They act as co-factors, catalysts or inhibitors of all enzymes in the body .
Patients and Methods: B

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Publication Date
Wed Dec 01 2021
Journal Name
Baghdad Science Journal
Study of Certain Biomarkers in Iraqi Female Patients with Breast Cancer

The prospective study has been designed to determine some biomarkers in Iraqi female patients with
breast cancer. The current study contained 30 patients whose tissue samples have been collected from
hospitals in Medical City in Baghdad after consent patients themselves and used immunohistochemical
technique to determine these markers. The results showed a significant correlation between ER and PR tissue
markers (Sig = 0.000) and a significant correlation between cyclin E phenotype and cyclin E intensity (Sig =
0.001).

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Publication Date
Sun Sep 06 2009
Journal Name
Baghdad Science Journal
Cox proportion hazard model for patients with hepatitis disease in Iraq

Cox regression model have been used to estimate proportion hazard model for patients with hepatitis disease recorded in Gastrointestinal and Hepatic diseases Hospital in Iraq for (2002 -2005). Data consists of (age, gender, survival time terminal stat). A Kaplan-Meier method has been applied to estimate survival function and hazerd function.

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Publication Date
Tue Apr 01 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Psychological Problems of Patients with Implantable Cardioverter Defibrillators in Baghdad City.

Background: Patients with an Implantable Cardiovertor Defibrillation (ICD) describe psychological problems such as depression, anxiety, and stress. To achieve the full benefits of the device, patient must maintain their psychological status within good levels.
Objectives: The major objectives of this study were to determine the main psychological problems in adult patients with an ICD and to find out the relationship between Psychological problems in patients with ICD and some demographic characteristics of patients with ICD.
Patients and Methods: A Descriptive analytical study was carried out from January 25, 2011 to March 20, 2012 in order to determine Psychological problems of patients with ICD. The sample was selected by A purp

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Publication Date
Sun Apr 04 2010
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Estimation of Antibodies against Saccharomyces Cerevisiae in Patients with Indeterminate Colitis

Background: Indeterminate colitis (IC) originally referred to those 10–15% of cases of inflammatory bowel disease (IBD) in which there was difficulty distinguishing between ulcerative colitis (UC) and Crohn’s disease (CD) in the colectomy specimen and histopathology examination. However, IC is increasingly used when a definitive diagnosis of UC or CD cannot be made at colonoscopy examination, colonic biopsies or at colectomy. The diagnostic difficulties may explain the variably reported prevalence of IC. Clinically, most patients with IC evolve to a definite diagnosis of UC or CD on follow up.
Patients and methods: PATIENTS GROUP: Consisted of 80 patients with indeterminate colitis (IC), their ag

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Publication Date
Sun Mar 01 2015
Journal Name
Baghdad Science Journal
Assessment of Serum Prolactin Level in Patients Women with Rheumatoid Arthritis

The prolactin hormone played role in the many autoimmune disorders. To determine the importance of high levels of prolactin in triggering rheumatoid arthritis, thirty patient's women with hyperprolactinemia aged (20-45) years old have been investigated and compared with twenty five healthy individuals. All the studied groups were carried out to measure the concentration of citrulinated peptide(CCP) by enzyme linked immunosorbent assay( ELISA), antikeratin antibodies (AKA)and antinuclear antibodies(ANA) by indirect fluorescent assay IFAT. There was a significant elevation of CCP concentration compared with control groups (P< 0.05). The percentage of antikeratin antibodies and antinuclear antibodies was (20%, 10%) respectively, and

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Publication Date
Sun Sep 07 2008
Journal Name
Baghdad Science Journal
A Study of some biochemical parameters in patients with &#61538;- thalassemia

Serum levels of iron,copper,ceruloplasmin and transferrine were estimated in three groups of patients with ?- thalassemia: 24 patients have splenectomy thalassemia major, 29 patients have non splenectomy thalassemia major and 19 patients have thalassemia intermedia , data were compared to normal and pathological controls (anemia and minor). There were significant increase in trace element levels in all studied groups of pateints as compared to normal and pathological controls. Also there were a significant increase in ceruloplasmin levels,While the result revealed that there were a significant decrease in transferrine levels in all groups of patients studied as compared to normal and pathological controls. The result also indicate that the

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Publication Date
Sun Jan 03 2010
Journal Name
Journal Of The Faculty Of Medicine Baghdad
CD-Markers as an immunological aspect in patients with visceral leishmaniasis

Back ground: Visceral leishmaniasis is an endemic protozoan disease in Iraq. Recovery from this disease confers a solid and permanent immunity. Immunological assessment of our patients was carried out and the results showed a significant reduction in the percentage of CD3, CD56 and a significant increase in the percentage of CD19 in the peripheral blood lymphocyte of VL in comparison with control group.
Patients and methods: Indirect immunofluorescence technique analysis was performed to detect the percentage of CD3, CD19and CD56 positive lymphocytes.
Results: Our results in the patients groups showed decrease in the percentage of CD3, CD56 and increase in the percentage of CD19. Follow up of patients after

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Publication Date
Wed Dec 30 2015
Journal Name
Al-kindy College Medical Journal
Evaluation Study of Patients Infected with Chronic Hepatitis C in Iraq

Background: ;Hepatitis C virus (HCV) is a major cause of chronic liver disease. Approximately 85% of patients acutely infected with HCV progress to chronic liver disease with persistence of HCV-RNA for more than 6 months Among patients with chronic HCV infection , 15-20% progress to end-stage liver disease main transmission methods of the virus is by : blood and blood products ; sharing needles and acupuncture .Objective: To evaluate Iraqi patients infected with chronic HCV, including their treatment, and factors that affect their response to treatment .Methods :This study was performed at Gastroenterology and Hepatology hospital in Baghdad from January 2011 to March 2012.The study enrolled 90 patients with HCV Antibody positive (Ab +ve)

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Publication Date
Sun Oct 02 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Carotid Intima-Media Thickness in 100 Iraqi Patients with Hand Osteoarthritis

Background: Hand osteoarthritis (HOA) is a common joint disorder leading to considerable pain and with substantial impact on hand function. Carotid intima-media thickness (CIMT) is a measurable index of the presence of atherosclerosis. Increased CIMT is associated with increased cardiovascular mortality and morbidity, so early diagnosis and management may improve quality of life.
Objective: To assess the relationship between carotid intima-media thickness (CIMT) and hand osteoarthritis (HOA), and to evaluate the predictors of this relationship.
Patients and Methods: One hundred Iraqi HOA patients and 100 healthy controls were included in this study. Full history was taken and complete clinical examination was done for all patients

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