There are many diseases that affect the arteries, especially those related to their elasticity and stiffness, and they can be guessed by estimating and calculating the modulus of elasticity. Hence, the accurate calculation of the elastic modulus leads to an accurate assessment of these diseases, especially in their early stages, which can contribute to the treatment of these diseases early. Most of the calculations used the one-dimensional (1D) modulus of elasticity. From a mechanical point of view, the stresses to which the artery is subjected are not one-dimensional, but three-dimensional. Therefore, estimating at least a two-dimensional (2D) modulus of elasticity will necessarily be more accurate. To the knowledge of researchers, there is a lack of published research on this subject, as well as a paucity of research that designed and implemented a 2D tensile testing device (2DTTD). However, there is no inspection of arterial flexibility and elasticity using the 2DTTD adequately studied before. Therefore, the aim of this work is to design and implement the 2DTTD to scrutinize if there is a difference between the 1D and 2D tensile examination. Different sized rectangular silicone specimens were manually fabricated; they were tested individually using the fabricated 2DTTD, which mainly comprises four actuators synchronously working with the same velocity and axial load force, two at each axis. As expected using the 2DTTD, the dimensions of the specimen remarkably influence the tensile testing results; the strain and stress rates and the modulus of elasticity were influenced. To validate the acquired 2D tensile testing results, the 1D tensile testing was performed using the same fabricated 2DTTD and compared to results gained using another tensile testing apparatus. During the verification process, the input data for models calibration were sufficiently and accurately provided. The results showed reasonable precision and reliability in calculations of the 2D stress and strain rates during the whole deformation process. Each mechanical device that has been used has the possibility to stretch and squeeze the sample and log the change in the specimen elongation. The authors thought that the present experimental methodology was applied to the linear mechanical device successfully, where the encoder that is attached to tested samples was in the principal direction. The present method is used to measure the deformation in a manner that differs from the traditional digital image correlation method, which required a toolset that is more expensive, where it incorporates high-accuracy optical equipment.