Synthesis and Identification of Some New Derivatives of Schiff bases Compounds and study their Biological activity

Ibtisam K Jassim; Nisreen H. Karam; Kaleda A. Aomran

Details

Publication Date

Tue Jul 01 2008

Journal Name

D

Choose Citation Style

Statistics

View publication

11

Statistics

Synthesis and Identification of Some New Derivatives of Schiff bases Compounds and study their Biological activity

Ibtisam K Jassim

Nisreen H. Karam

Kaleda A. Aomran

...Show More Authors

A new series of Schiff bases compounds , containing an azomethine linkage was synthesized and expected to be biologically active .The structures of these compounds were identified by IR , Uv/vis spectra , melting points and followed by T.L.C.The biological activity of these compounds was studied

Publication Date

Sun Jan 01 2017

Journal Name

Al-mustansiriyah

Synthesis, Spectroscopic and Biological Studies of a New Some Complexes with N-Pyridin-2-Ylmethyl-Benzene-1, 2Diamine

Shaimaa

...Show More Authors

Publication Date

Sun Dec 01 2024

Journal Name

Russian Journal Of General Chemistry

Synthesis, Characterization, and Biological Evaluation for New Derivatives Based on 2Сhloro-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]acetamide

N. M.

K. A.

H. A.

J. H.

H. S.

R. K.

...Show More Authors

View Publication

Publication Date

Sun Dec 01 2024

Journal Name

Russian Journal Of General Chemistry

Synthesis, Characterization, and Biological Evaluation for New Derivatives Based on 2Сhloro-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]acetamide

N. M.

K. A.

H. A.

J. H.

H. S.

R. K.

...Show More Authors

View Publication

Publication Date

Tue May 29 2018

Journal Name

Journal Of Pharmaceutical And Scientific Research

Synthesis and characterization of substituted 1, 2,4-triazole and their derivatives on poly ethylene

1

2

4-triazole

1

2

4-triazole-3-one

1

2

4-triazole-3-thione

Rana

Zainab

Entesar

...Show More Authors

Abstract New derivatives of 1,2,4- triazole , 1,2,4-triazole -3-one and 1,2,4-triazole-3-thione were obtained through this research. Acid hydrazide derivative was present from reaction of poly acryloyl chloride with hydrazine hydrate in presence of DMF as a solvent then reacted with benzonitrile and its derivatives to give 1,2,4-triazole derivatives. After that reaction of poly acryloyl chloride with semicarbazide and semithiocarbazide to form semicarbazone and semithiocarbazone derivatives respectively. Finally, closing of semicarbazone and semithiocarbazone derivatives with 2% NaOH gave 1,2,4-triazole -3-one and 1,2,4-triazole-4-thione derivatives respectively. These new synthesized products have been characterized by infrared, 1 H-n

Publication Date

Fri Dec 01 2023

Journal Name

Russian Journal Of General Chemistry

Preparation, Characterization, and Biological Activity of Mixed Schiff Base Ligand Complexes with Amino Acid L-Proline

Taghreed

...Show More Authors

View Publication

(10)

Publication Date

Fri Dec 01 2023

Journal Name

Russian Journal Of General Chemistry

Preparation, Characterization, and Biological Activity of Mixed Schiff Base Ligand Complexes with Amino Acid L-Proline

N. M.

S. M. H.

Mazin Hasan

Taghreed H.

Salam R.

Aly

...Show More Authors

(10)

Publication Date

Fri Dec 01 2023

Journal Name

Russian Journal Of General Chemistry

Preparation, Characterization, and Biological Activity of Mixed Schiff Base Ligand Complexes with Amino Acid L-Proline

N. M.

S. M. H.

M. H.

Taghreed H.

S. R.

A.

...Show More Authors

(10)

Publication Date

Sun Oct 06 1996

Journal Name

Iraqi Journal Of Chemistry

Synthesis of new Schiff bases derived from [3-amino-3-C-cyano-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

Y. Ali

M. J.

Khalid Waleed S

...Show More Authors

Aromatic Schiff-bases are known to have antibacterial activity, but most of these compounds are sparingly soluble in water. The present work describes the synthesis of new Schiff-bases derived from branched aminosugars. Treatment of 3-Amino-3-Cyano-3-Deoxy-1,2:5,6-Di-O-Isopropylene-α-D-Allofuranose (1) with the aldehydes (2) under reflux in methanol afforded the Schiff-bases (3) in good yields. The new Schiff-bases were in accord with their NMR, IR spectral data and elemental analysis.

Preview PDF

Publication Date

Fri Jul 05 2013

Journal Name

Pharmacie Globale International Journal Of Comprehensive Pharmacy

SYNTHESIS OF NEW PROPRANOLOL DERIVATIVES AS POSSIBLE PRODRUGS

propranolol

prodrugs

bioavailability

first- pass metabolism

Mohammed H

May Mohammed Jawad

Amera Abbas

...Show More Authors

Propranolol is a nonselective-adrenergic blocker used in the treatment of hypertension, cardiac arrhythmias, and angina pectoris. A significant problem in propranolol therapy is that it undergoes extensive presystemic metabolism after oral administration leading to reduced bioavailability. In this study, two new propranolol derivatives have been designed, synthesized and characterized. These compounds were formed by acylation of propranolol followed by nucleophilic substitution reaction of acylated propranolol, these derivatives were analyzed for IR, CHN, melting points, and evaluated for their lipophilic properties compared with propranolol. The lower partition coefficient of these two derivatives revealed that the prodrug approach may be

Publication Date

Mon Mar 11 2019

Journal Name

Baghdad Science Journal

Synthesis and Antimicrobial Schreening of New 4,5,6,7-Tatra Hydro Benzo Thiophene Derivatives

Antimicrobial Activity

2-Azetidinone

3-Oxazepane4-Thiazolidinone

Schiffbases

Tetrazole

Tetra hydrobenzo thiophene.

Zainab

...Show More Authors

A group of derivatives for compounds 2-Amino-3-carboxy-4,5,6,7-tetra hydrobenz -othiophene bearing different heterocyclic moieties such as Schiff bases. B-Lactum, 4-thiazolidinone.1,3-oxazepan. The newly synthesized derivatives have been supported by spectral data FT-IR, H¹-NMR. All the synthesized compounds were screened for their antimicrobial activities against gram-positive and gram-negative bacteria as reference.

View Publication Preview PDF

(3)

1 2 ... 32 33 34 35 ... 2677 2678