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Formulation and In Vitro Evaluation of Mucoadhesive Antimicrobial Vaginal Tablets of Ciprofloxacin Hydrochloride
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Ciprofloxacin is a broad spectrum fluoroquinolone, effective in the treatment of a wide range of infections, including genitourinary tract infections.In this study, bioadhesive vaginal tablets of ciprofloxacin hydrochloride were prepared by direct compression method using a combination of bioadhesivepolymers carbopol 934P(Cp), carboxymethylcellulose (CMC) and sodium alginate (SA) in different ratios.The prepared tablet formulations were characterized by measuring their swelling capacity, surface pH, bioadhesive properties, and in-vitro drug dissolution. It was found that the bioadhesive force was directly proportional to carbopol 934P content in different formulae and was further enhanced by the inclusion of carboxymethylcellulose. Swelling studies indicated that formulae containing a combination of carbopol 934P and sodium alginate or carboxymethylcellulose had greater swelling index than those containing carbopol 934P alone. Formulations containing Carbopol 934P and carboxymethylcellulose were found to swell to a greater extent than those composed of similar ratios of carbopol and sodium alginate. In vitro drug release study showed that the release of ciprofloxacin hydrochloride from formulae containing carboxymethylcellulose was faster than from those containing sodium alginate.Formula F5 composed of CP/CMC in a ratio of 2:1 showed moderate swelling, suitable bioadhesion and retardation of drug release. Thus, it may be considered a good candidate as a base for bioadhesive vaginal tablet

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Publication Date
Tue Feb 11 2025
Journal Name
Al–bahith Al–a'alami
News in Brief and Their Role in Public Understanding of News Content in Iraqi Satellite TV
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News feeds are at the forefront of news forms that are close to the public's attention for their rapid news content in two directions:

  1. its speed in summarizing events in one or two sentences easy to be understood and realized.
  2. highlight the most important contents of screenings or news broadcast.

The researchers felt that the importance of these brief news compared to news broadcast, breaking news and news subtitle are still ambiguous, as well as their contents.

The researchers selected the city of Baghdad as a community to research and prepare a questionnaire form containing (11) questions.

The questionnaires were distributed to a non-relative stratified

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Publication Date
Wed Dec 30 2015
Journal Name
College Of Islamic Sciences
Constants of blood money in the Koran   And its variables in the custom prevailing in Iraq
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Praise be to Allah, the Lord of the Worlds.
          Because it has a prominent role in the life of the Muslim person in particular, and in the stability, security, and safety of society in general, I found it appropriate to participate even a little in solving some of the problems that arise in the nation, and that Adello Badawi in this important issue that concerns everyone without exception And that I show that there are constants in the Koran, from which the scholars of the Ummah derived their evidence on this subject, and that there have been variables have occurred in some Islamic societies, in the issue of blood money that deserves the victim and his family, has allocated talk

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Publication Date
Tue Feb 27 2024
Journal Name
Pharmacia
Association of the rs1801133 and rs1801131 polymorphisms in the MTHFR gene and the adverse drug reaction of methotrexate treatment in a sample of Iraqi rheumatoid arthritis patients
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Background: Methotrexate is one of the mainstays for treating rheumatoid arthritis (RA) with a wide range of adverse drug reactions, however, it’s the relationship between adverse drug reactions and genetic polymorphism remains to be highlighted, and there is a lack of studies concerning Arabic Iraqi population regarding this aspect.

Objective: Evaluate the association between genetic mutations in the MTHFR gene in SNPs (rs1801133G>A and rs1801131T>G) on the adverse drug reaction for RA Iraqi patients.

Methods: An observational study, that involved 95 Iraqi RA patients with established RA. Patien

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Publication Date
Sat Dec 01 2007
Journal Name
Journal Of Economics And Administrative Sciences
The analysis of time series considers one of the mathematical and statistical methods in explanation of the nature phenomena and its manner in a specific time period.
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The analysis of time series considers one of the mathematical and statistical methods in explanation of the nature phenomena and its manner in a specific time period.

Because the studying of time series can get by building, analysis the models and then forecasting gives the priority for the practicing in different fields, therefore the identification and selection of the model is of great importance in spite of its difficulties.

The selection of a standard methods has the ability for estimation the errors in the estimated the parameters for the model, and there will be a balance between the suitability and the simplicity of the model.

In the analysis of d

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Publication Date
Fri Mar 01 2019
Journal Name
Al-khwarizmi Engineering Journal
Experimental Study of Drug Delivery system for Prednisolone Loaded and Released by Mesoporous Silica MCM-41
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In the present study, nanoporous material type MCM-41 was prepared by the sol-gel technique and was used as a carrier for prednisolone (PRD) drug delivery. The structural properties of mesoporous were fully characterized by X-ray diffraction (XRD), N2 adsorption /desorption and Fourier-transform infrared (FTIR). The mass transfer in term of adsorption process (loading) and desorption process (releasing) properties were investigated. The maximum drug loading efficiency was equal to 38% and 47.5% at different concentrations. The PRD released was prudently studied in water media of pH 6.8 simulated body fluid (SBF) in according to "United State Pharmacopeia (USP38)". The results proved that the release of prednisolone from MCM-41

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Publication Date
Sun Apr 29 2018
Journal Name
Iraqi Journal Of Science
FIA– Spectrophotometric methods for the determination of Naringenin in supplements and urine samples using diazotization coupling reactions
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Direct FIA methods for estimation of Naringenin (NG) in different samples were proposed. These methods are based on diazotization coupling reactions of two reagents: method (A) p-chloroaniline (PCA) and method (B) procaine hydrochloride (PRH) with NG in basic medium. Yellow dyes with maximum absorption at 416 and 415 nm were formed respectively. Calibration curves were constructed over different NG concentrations, linearity was from 1- 70 and 1- 40 µgmL-1 with detection limits of 0.55 and 0.24 µgmL-1 for (A) and (B) respectively. All analytical variables involved in the FIA procedure were evaluated and optimized. The established methods were successfully applied for the determination of NG in its supplements and u

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Publication Date
Wed Feb 01 2017
Journal Name
Journal Of Economics And Administrative Sciences
The role of accounting responsibility in the success of the reform of financial and administrative / applied research in high School
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The reform process is a dynamic process going on, especially the administrative and financial reform, which contributes to the work and directing operations towards success and continuous development, which requires determining the validity and the responsibility and the rights and duties of all officials in the school settings (within the formations educational institutions) for the purpose of reducing the administrative and financial corruption, and then ensure management efficient and effective way by taking advantage of the physical, financial and human resources available to achieve the greatest benefit at the lowest cost to the fact that the follow-up performance on an ongoing basis in accordance with the specific of powers

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Publication Date
Sat Sep 23 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Effect of Interaction Betw·een Phosphorus and Zink in Some Morphological Features of Two Varieties of Wheat Grown in Gypsum Soil
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A  biological   experirne.rit   was  CQhducted ·ll1  the   (Ibn-  Al­

Haitham).  University        of   Baghdad  for   growing   seasens   on   of

2004/2005 (by using gypsum soil taken from Al- Doar area I Salah Al­ Dean provinc)  to stucl·- the effect three levels of phosphorus (0, 400,

SOO)rng ! pot and four  levels of zinc (0, 10,.. J 5, 2.0) tngf I pot on some

features of two  varieties -Qf    wheat, (triticum aestivurn var. rateh)and

(Triticum aestiv1lm Var. Ipa 99)..

R't

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Publication Date
Sun Sep 15 2019
Journal Name
Al-academy
Use of Multimedia in the Design of Educational Websites and their Role in Enhancing the Cognitive Aspect of the Learner
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Multimedia is one of the most important elements of modern educational media and must be used in educational websites in order to disseminate knowledge on a large scale and should be used to provide scientific information to all, as the current research tried to explore the possibilities of employing them in the design of educational websites and highlight their role in promoting the scientific aspects of the user. This study included four axes, the first of which was devoted to the introduction which includes the problem of research, its importance, objectives and its objective, temporal and spatial limitations, which were limited to the study of the main pages of Arabic educational websites published in 2019. The second axis contained th

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Publication Date
Sat Jun 03 2023
Journal Name
Iraqi Journal Of Science
Measuring the concentration of Suspended Particulate Matter and some heavy metals in air of two areas of Rusafa in Baghdad
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This study aimed to detect the present levels and distribution of air pollutants such as SPM, Pb, Cr, Cd , and Ni , in two urban sites within Al- Rusafa side in Baghdad city (Al-Waziriya as industrial site and Al-Andalus square as commercial site). Measurements were carried out from November 2013 until June 2014. SPM, Pb, Cr, Cd , and Ni were measured using Air intake device(Sniffer) . The average minimum concentrations of SPM, Pb, Cr, Cd , and Ni were 588 μg/m3, 2.8 μg/m3, 15.6 μg/m3, 0.1 μg/m3, and 6.3 μg/m3. While the average maximum concentrations were 723 μg/m3 , 3.4 μg/m3 , 21.7 μg/m3 , 0.125 μg/m3 , and 6.8 μg/m3 , respectively. The results indicate that commercial site was more polluted with SPM , Pb , and Ni compared t

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