Synthesis and Charactrization of New Schiff Base Derived from
PVA and Erythroascorbic Acid Derivative and Study Its Effect on
the Activity of ACh Enzyme (In Vitro)
Schiff base
PVA
Acetylcholinesterase
Schiff base derived from PVA and Erythroascorbic acid derivative (pentulosono-ɣ-lactone-2, 3-enedianisoate) was synthesized and characterized by Thin Layer Chromatography (TLC) and FTIR spectra, aldehyde was also characterized by (U.V-Vis), 1HNMR, 13CNMR and mass spectra. The inhibitory effect of prepared polymer on the activity of human serum Cholinesrerase has been studied in vitro. The polymer showed a remarkable activity at low concentration (4.5*10-3 – 4.5*10-8 M).
