The present investigation aims to determine the effects of aflatoxin B1 (AFB1) on biotransformation and antioxidant genes and the protective effects of curcumin, present in turmeric (Curcuma longa) powder (TMP). Specifically, the study included four groups of albino mice were fed for 30 days on diet Group I: Control, Group II: animals fed on the conventional basal diet supplemented with 0.5% food grade TMP that supplied 74 mg/kg total curcuminoids. Group III contained animals reared on conventional basal diet supplemented with 1.0 ppm AFB1 supplied by ground aflatoxin culture material (760 ppm AFB1). Finally, Group IV comprised of albino mice fed with basal diet supplemented with 1.0 ppm AFB1 and 0.5% TMP that supplied 74 mg/kg of the body weight. After treatment, a number of physical parameters were assessed (gain in body weight, average quantity of feed intake and relative liver weight) and it was found that the subjects fed on diet containing curcumin and aflatoxin B1experienced ameliorative effect on the impact of aflatoxin B1 and performed better on growth and liver weight parameters. RNA extracted from the mice liver successfully was subjected to quantitative real time PCR analysis (Q PCR) and the results revealed no high significant difference in the expression of CAT gene between studied groups with probability value ≥0.005. However, at the other hand a decreased in expression statically of SOD, GPx, GST, EH genes was observed while there was an increased Synchronous and consistent expression of CYP1A1 and CYP2H1 genes display in the studied groups in the current study.
Plants and their extracts preparations have been used as medicines against infectious diseases. In present work, Cassia senna (leaves), Piper nigrum (fruits) were extracted with different organic solvents to investigate their antifungal activities in vitro. However, the effective of plant extracts against some pathologic fungi (Tricophyton rubrum, T. tonsurans, T. violaceum, Microsporum audouinii, M. canis and M. gypseum) were evaluated at concentrations ranged between (0.005–5%) using agar diffusion methods and compared with standard antifungal drug (Clotrimazole). Results showed that methanol extract of C. senna and ethanol extract of P. nigrum displayed excellent inhibition on dermatophytes compared with standard antifungal drug, th
... Show MoreSolubility problem of many of effective pharmaceutical molecules are still one of the major obstacle in theformulation of such molecules. Candesartan cilexetil (CC) is angiotensin II receptor antagonist with very low water solubility and this result in low and variable bioavailability. Self- emulsifying drug delivery system (SEDDS) showed promising result in overcoming solubility problem of many drug molecules. CC was prepared as SEDDS by using novel combination of two surfactants (tween 80 and cremophore EL) and tetraglycol as cosurfactant, in addition to the use of triacetin as oil. Different tests were performed in order to confirm the stability of the final product which includes thermodynamic study, determination of self-emulsificat
... Show MoreFusion can be described as the process of integrating information resulting from the collection of two or more images from different sources to form a single integrated image. This image will be more productive, informative, descriptive and qualitative as compared to original input images or individual images. Fusion technology in medical images is useful for the purpose of diagnosing disease and robot surgery for physicians. This paper describes different techniques for the fusion of medical images and their quality studies based on quantitative statistical analysis by studying the statistical characteristics of the image targets in the region of the edges and studying the differences between the classes in the image and the calculation
... Show MoreThis research is devoted to investigate the behavior and performance of reinforced concrete beams strengthened with externally bonded Carbon Fiber Reinforced Polymer (CFRP) laminates under the effect of torsion. In this study a theoretical analysis has been conducted using finite element code ANSYS. Six previously tested beams are used to investigate reinforced concrete beams behavior
under torsion, two of them are solid and the rest are box-section beams. Also, two beams are without CFRP reinforcement, which are used as control beams for the strengthened one, and the other four beams are strengthened with CFRP laminates with different number of layers and spacing. Numerical investigation is conducted on these beams, and comparisons b
Chromium oxide nanoparticles were synthesized using cauliflower extract by two methods: simple chemical method and the sol-gel method. These technologies are new, environmentally friendly and cheap. Cauliflower contains plant materials and biomolecules (chromium, phenols, alkalis, vitamins, amino acids, quinones, etc. (that convert chromium chloride hexahydrate (CrCl3.6H2O) into chromium nanoparticles. The plant extracts also act as diluents, stabilizers and anti-caking agents. X-ray diffraction (XRD) analysis showed that the size of the crystals decreased from (36.1 to 57.8) nm using the simple chemical method to (13.31 to 20.68) nm of Cr2O3 using sol-gel.
... Show MoreIn this study, nanocomposites have been prepared by adding
multiwall carbon nanotubes (MWCNTs) with weight ratios (0, 2, 3,
4, 5) wt% to epoxy resin. The samples were prepared by hand lay-up
method. Influence of an applied load before and after immersion in
sodium hydroxide (NaOH) of normality (0.3N) for (15 days) at
laboratory temperature on wear rate of Ep/MWCNTs
nanocomposites was studied. The results showed that wear rate
increases with increasing the applied load for the as prepared and
immersed samples and after immersion. It was also found that epoxy
resin reinforced with MWCNTs has wear rate less than neat epoxy.
The sample (Ep + 5wt% of MWCNTs) has lower wear rate. The
immersion effect in base so
A new technique to study the telegraph equation, mostly familiar as damped wave equation is introduced in this study. This phenomenon is mostly rising in electromagnetic influences and production of electric signals. The proposed technique called as He-Fractional Laplace technique with help of Homotopy perturbation is utilized to found the exact and nearly approximated results of differential model and numerical example of telegraph equation or damped wave equation in this article. The most unique term of this technique is that, there is no worry to find the next iteration by integration in recurrence relation. As fractional Laplace integral transformation has some limitations in non-linear terms, to get the result of nonlinear term in
... Show MoreIn most Reinforced Concrete (RC) buildings, the cross-section size of rectangular columns that conventionally used in these structures is larger than the thickness of their partitions. Consequently, a part of the column is protruded out of the wall which has some architectural disadvantages. Reducing the column size by using high strength concrete will result in slender column, thus the stability problem may be occurred. The stability problem is difficult to be overcome with rectangular columns. This paper study the effectiveness of using new types of columns called Specially Shaped Reinforced Concrete (SSRC) columns. Besides, the use of SSRC columns provides many structural advantage
Digital Elevation Model (DEM) is one of the developed techniques for relief representation. The definition of a DEM construction is the modeling technique of earth surface from existing data. DEM plays a role as one of the fundamental information requirement that has been generally utilized in GIS data structures. The main aim of this research is to present a methodology for assessing DEMs generation methods. The DEMs data will be extracted from open source data e.g. Google Earth. The tested data will be compared with data produced from formal institutions such as General Directorate of Surveying. The study area has been chosen in south of Iraq (Al-Gharraf / Dhi Qar governorate. The methods of DEMs creation are kri
... Show MoreWe examine the integrability in terms of Painlevè analysis for several models of higher order nonlinear solitary wave equations which were recently derived by Christou. Our results point out that these equations do not possess Painlevè property and fail the Painlevè test for some special values of the coefficients; and that indicates a non-integrability criteria of the equations by means of the Painlevè integrability.