Felodipine is a calcium-channel blocker with low aqueous solubility and bioavailability. Lipid dosage forms are attractive delivery systems for such hydrophobic drug molecules. Nanoemulsion (NE) is one of the popular methods that has been used to solve the dispersibility problems of many drugs. Felodipine was formulated as a NE utilizing oleic acid as an oil phase, tween 80 and tween 60 as surfactants and ethanol as a co-surfactant. Eight formulas were prepared, and different tests were performed to ensure the stability of the NEs, such as particle size, polydispersity index, zeta potential, dilution test, drug content, viscosity and in-vitro drug release. Result

The objective of the study was to develop microneedle (MN) patch, with suitable properties to ensure the delivery of a therapeutic level of lornoxicam (LXM) in a period suitable to replace parenteral administration in patients, especially those who fear needles. The used polymers were cold water-soluble polyvinyl alcohol (PVA) and polyvinylpyrrolidone (PVP) of low molecular weight with PEG 400 as plasticizer and Tween 80 (to enhance the release) using micro molding technique. Patches were studied for needle morphology, drug content, axial fracture force measurement and drug release while the optimized formulas were further subjected to pH measurement, folding endurance, ex vivo permeation study, histopathology study, stability study and

The main object of the current work was to determine the antifungal efficiency of secondary metabolites product called synephrine that extracted from Citrus sinesis peels and the ability of synephrine to biosynthesis gold nanoparticles from HAucl4 which consider environmentally favourable method, then determine their activity against pathogenic human dermatophyte. The identification of synephrine done by Thin layer chromatography (TLC), High Performance Liquid Chromatography (HPLC) and The Fourier Transform Infrared (FTIR). The characterization of gold nanoparticles by using Ultra Violet-Visible Spectroscopy (UV-Vis), Field – Emission Scanning Electron Microscopy (FESEM) and Fourier Transform Infrared (FTIR), confirmed the biosynt

A sensitive and accurate colorimetric method was developed for the determination of the Sitagliptin phosphate monohydrate, here and after will be named Sitagliptin, in its pure and pharmaceutical form. The suggested approach is based on boosting the sensitivity of the traditional spectrometric methods by derivatizing Sitagliptin into a colored product that absorbs the visible spectrum at 573 nm. The proposed method has effectively improved the sensitivity and the limit of detection for the analysis of Sitagliptin. A linear calibration curve was obtained over the concentration range of 0.1-10 μg/ml with a correlation coefficient of 0.9983. The calculated recovery was within the range of 98.98–100.11%. While the limit of detection LOD and

The present study evaluates the insecticidal activity of (Acetone, 80% Methanol and water) crude leaf extract of AdhatodavasicaagainstBemisiatabaci. The extracts of (Acetone, Methanol 80%) showed 100, 86.6% mortality of nymphsBemisiatabaci at 5% concentration. Then the extracts of (Acetone, Methanol 80%) showed 100, 90% mortality of pupaBemisiatabaci at 5% concentration. Phytochemical screening revealed the presence of (Flavones, Volatiles oils, Tannins, Saponines, Glycosides, Alkaloids,Resins and Terpenoids)in methanol80% crude extract. It can be concluded that the acetone and methanol crude leaf extract of A. vasicaNees can cause mortality in (nymphs, pupa) Bemisiatabaci, so it can be used asinsecticides.

A study was carried out in the vineyard at Al- sowayra in the Waset Province to study the effect of boron spray on cluster and fruits traits characteristics of grape cultivar . Borax used  was as a source of boron at the concentrations (0.0 , 0.1, 0.2, 0.3, 0.4 and 0.5 ) g / l . Water plus Wetting agent   (0.05 g/l detergent) was sprayed to induce faom and reduce water surface tension. The spray was implemented twice, first was one week before blooming and the second was after fruit set. Results showed that spray treatment by boron increased. weight and volume of berries and increased cluster's weight bunch length and diameter besides the increased number of Fruits in bunch also Total Soluble Solids (Tss%) was increased wh

The research problem has crystallized and in light of these capabilities, the level of performance depends on the application of modern training methods based on actual experimentation, and those methods aim to develop the components of achievement in this competition, including the quantities of exerting the distinctive strength with speed for the arms and feet, which reflects on good skillful performance because the skill of shooting by jumping forward and high forms A major role in achieving goals during the competition that qualifies the team to win, and through the follow-up of the researcher in the field and academic field, I noticed that there is a weakness in some physical abilities, which affects performance and skill level

Asthma is a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role. The treatment guidelines recommend theuse of a second controller drug in addition to medium doses of inhaled corticosteroids (ICSs) rather than the use of high doses ICS alone in the treatment of moderate-severe persistent asthma. This study was conducted to compare the clinical efficacy and safety of three treatment regimens in Iraqi patients with moderate-severe persistent asthma.The study included three groups; each group included 15 patients. Patients were administered beclomethasone inhaler alone 1500-2000 μg/day, beclomethasone inhaler 750-1000 μg/day plus oral controlled release aminophylline tablets 450 mg/day or

In the last few years, fiber-coupled diode lasers have shown massive applications in many fields of communication and scientific research. Particularly, the pumping of solid-state lasers is a key application for more powerful diode lasers enabling good solutions in various laser micro methods like metal cutting, sintering, structuring as well as drilling. In this work, a simple beam shaping method is demonstrated for coupling a high-power semiconductor laser diode into multi-mode fiber optic using optical lenses. The optical lenses as beam transformation components are utilized to reshape the asymmetrical irradiation of the diode laser bar and to circularize the laser beam. Using this simple method, compact, high-output-power, and high-b