The study aimed to evaluate Glucagon-Like Peptide-1 levels in Polycystic ovary syndrome (PCOS) infertile female with Diabetes Mellitus (DM) and compare the results with control group, also, to find the correlation for GLP-1 with Luteinizing hormone (LH), Follicle stimulating hormone (FSH) and LH/FSH ratio that may be used in prediction atherosclerosis in these patients. The study included nineteen women with age ranged (30-40) years and BMI ranged between (30-35) Kg/m 2. Subjects were divided into two groups: group (1) consist of (45) females as a healthy control and group (2) consist of (45) infertile females with PCOS and DM as complication. Fasting serum glucose was determined by using commercial kits (Biolabo SA-France); LH, FSH, prolactin were determined by ELISA, fasting serum insulin was determined by using ELISA kit (DRG-Germany). Insulin-resistance (IR) calculated by (HOMA-IR). FSH, LH, LH/FSH ratio and prolactin levels for all studied groups were measured. A highly significant elevation in prolactin, LH and LH/FSH ratio was found when G1 comparing with G2. While significant reduction seen in FSH levels in G2 comparing to G1. A high significant elevation in Fasting blood glucose,% HbA1C levels in patients group when comparing to healthy control. Results revealed a highly significant elevation in insulin, HOMA-IR and glucagon, while there are a significant reduction in GLP-1levels. There is significant positive correlation was found in GLP-1 levels with (FSH) in G1, while a significant negative correlation was observed in levels of GLP-1 and (FSH) inG2. A significant negative correlation was found in GLP-1 levels
Novel Biomarker in Polycystic Ovary Syndrome (PCOS) Infertile Females With Diabetes Mellitus Prone to Atherosclerosis
GLP-1
insulin resistance
PCOS
Publication Date
Sat Oct 01 2022
Journal Name
Environmental Advances
Stability and performance studies of emulsion liquid membrane on pesticides removal using mixture of Fe3O4Â nanoparticles and span80
The current study investigated the impact of nonionic surfactant span 80 in the existence of Fe3O4 magnetic nanoparticles on the emulsification of mixture of kerosene as petroleum based organic solvents and corn oil as a green diluent in the ratio 1:1
HCl was used as internal phase and the stability of the emulsion was carried out. The proposed Pickering emulsion liquid membrane has been exploited to investigate it is ability in the extraction of Abamectin pesticides from aqueous solution without utilizing carrier agent. Further
the effects of experimental parameters on extraction efficiency and emulsion stability such as
homogenizer speed
emulsification speed
contact time
Fe3O4-Span 80 ratios
HCL concentration
internal to membrane volume ratio (I/O) and pH of the external feed solution were carried out. The results showed that more than 99% of Abamectin could be extracted at 10 min contact time with a minimum breakage percent of 0.52% at the optimal conditions. The kinetic of the extraction were studied and the mass transfer coefficient was found to be for external phase () of 1.2
interfacial reaction rate constant () of 5.83 and the overall mass transfer coefficient () of 3.91 . The results of recyclability of the PELM revealed that the emulsion stability and extraction efficiency was nearly unchanged after three cycles.
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