The immune infertility caused by anti-sperm antibodies (ASAs) represented about 10–20% of infertility among the couples. The ASAs interfere with sperm parameters such as sperm motility and sperm ability to penetrate cervical mucus, sperm-oocyte binding, and fertilization and embryo development. Objectives: The present study designed to assess semen analysis, presence of ASAs and DNA fragmentation index as well as correlation within these parameters in normzoospermic Iraqi subjects Patients, Materials, and Methods: A total number of Iraqi subjects (116) with range of age (20-51) years and their mean duration of infertility (4.70 ± 2.77). Seminal fluid for macroscopic and microscopic assessments done according to WHO 2010 criteria. The mixed agglutination reaction (MAR) test was used to assess their ASAs in semen (direct method), seminal plasma, and serum (indirect method) for both IgG and IgA classes of antibodies and their distribution among different parts of spermatozoa as a percentage. Results: The mean of IgG using the direct method was (23.88± 1.75) and for the indirect detection method the mean was (27.41± 2.41) with no significant difference (p > 0.05) between the two methods. While the direct method for IgA detection had a mean of 14.46 ± 1.76 and the indirect method of detection had a mean of 6.86 ± 0.39, there was a significant difference (P<0.05) between the two methods. In addition to that, the distribution of IgG and IgA detected by the direct method on sperm parts showed no significant difference except for the sperm tail, while the indirect method for IgA and IgG showed a significant difference in distribution on the sperm mid-piece. Conclusion: The correlation among sperm parameters and immunoglobulin using direct and indirect methods shows variations in significance also in the correlation between the direct and indirect methods according to distributions on the sperm surface.
Back ground: Viruses may be involved in the pathogenesis of Type 1 Diabetes Mellitus (T1DM), either through direct β-cell infection or as triggers of
autoimmunity.
Objective: To investigate the presence of specific anti- viral IgG antibodies for Coxsackie virus type B (CVB5), Poliovirus, and Adenovirus which proposed to be
involved in the etiology of T1DM.
Subjects & methods: A total of 60 Iraqi T1DM children were included in the presents study. They were new onset of the disease (diagnosis was from one week up
to five months). For the purpose of comparisons, 50 apparently healthy control subjects were selected. Serum IgG against Coxsackie virus type B5, Adenovirus type
3, 4, and 7, and Poliovac
Pregnancy-induced hypertension (PIH) is a major pregnancy complication that causes pregnant women mortality. Here, we had scrutinized the correlation between serum levels of -hCG and biochemical parameters in PIH. Serum samples were collected from eighty Iraqi women (forty women with pregnancy-induced hypertension as patients group, twenty normotensive pregnant women as a positive control, and twenty normotensive non-pregnant women as a negative control) all groups were diagnosed clinically. All -hCG hormone level was measured for all studied groups, also serum uric acid, albumin, and total protein levels were measured as biochemical parameters. Data analysis showed that serum level of -hCG hormone was significant increase (p≤
... Show MoreThis paper provides an attempt for modeling rate of penetration (ROP) for an Iraqi oil field with aid of mud logging data. Data of Umm Radhuma formation was selected for this modeling. These data include weight on bit, rotary speed, flow rate and mud density. A statistical approach was applied on these data for improving rate of penetration modeling. As result, an empirical linear ROP model has been developed with good fitness when compared with actual data. Also, a nonlinear regression analysis of different forms was attempted, and the results showed that the power model has good predicting capability with respect to other forms.
Background: In recent years, bone marrow angiogenesis is indicated to be involved in the pathogenesis and progression of certain hematological malignancies like acute leukemia, lymphomas, and multiple myeloma. Recent studies have suggested that bone marrow angiogenesis plays an important role in the pathogenesis of adult acute lymphoblastic leukemia and also has prognostic value in the disease.
Objectives: at the present study, bone marrow angiogenesis in ALL will be examined using immunohistochemical staining for CD34, and this will be correlated with various pathological, laboratory and clinical parameters.
Patients and methods: A retrospective cross-sectional study was done on 60 patients with acute lymphoblastic leukemia (32 ma
The monocyte chemo-attractant protein-1 (MCP-1) is one of the pro-inflammatory cytokines. It controls the passage and infiltration of monocytes, macrophages, natural killers, and T cells into the sites of inflammation. The aim of this study is to inspect the role of MCP-1 in maternal metabolic, physiological changes and pregnancy complications like gestational diabetes mellitus, dyslipidemia, and hypertension to develop pharmaceutical strategies for these complications. This study included ninety Iraqi women divided into three groups: thirty pregnant women in their first trimester as the P1 group; thirty pregnant women in their third trimester as the P2 group; and thirty healthy non-pregnant women as the control or C group. Se
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Background: Anti-RA33 antibodies and anti-CCP antibodies are highly specific markers for rheumatoid arthritis (RA), but are not detectable in all RA patients.
Anti-RA33 antibodies are directed to the heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2),while anti-CCP antibodies are directed to modified epitope on proteins that undergo conversion of amino acid arginine to citrullin by citrullination.
Objectives: The aim of this study was to show the correlation between anti-RA33 antibodies, anti-CCP antibodies and rheumatoid factor (RF) in terms of sensitivity and specificity for the diagnosis of rheumatoid arthritis in Iraqi patients.
Subjects and methods: This s
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Diabetes Mellitus (DM) is a chronic disease distributed worldwide and dominantly related to different types of diseases especially microbial infections, this study aimed to find the relationship between DM mouth microbiome and some demographic factors. Sixty saliva specimens and bacterial oral swabs were collected from randomly selected DM patients, including 29 females and 31 males enrolled in this study, which was obtained from the Al-Mustansiriya University national diabetes center in Baghdad, and other 40 apparently healthy people specimens and swabs were collected from 25 females and 15 males as a control group for the period starting November / 2021 to February / 2022. The results revealed that the most prevalent bacterial gener
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Background: Anemia is very common in patients with chronic kidney disease, and becoming almost universal in end stage renal disease, where dialysis or renal transplantation becoming the treatment of choice. High levels of hepcidin appear to accompany reduced renal function and serum ferritin may also be elevated.
Objectives: To classify anemia in hemodialysis patients and to display the correlations between the types of anemia and inflammatory parameters like hepcidin and ferritin according to vascular access of hemodialysis.
Patients and methods: This case-control study was conducted at Al-Hayat center for hemodialysis, and included 60 adult patients on hemodialysis. Also 20 healthy individuals were recruited as control group. Mea
Background: Periodontal diseases are bacterial infections of the gingiva, bone and attachment fibers that support the teeth and hold them in the jaw. α-amylase is an enzyme, produced mainly by parotid gland and it seems to play a role in maintaining mucosal immunity. Aims of the study: Determine the salivary levels of α-Amylase and flow rate and their correlations with clinical periodontal parameters(Plaque Index , Gingival Index , Bleeding on Probing , Probing Pocket Depth , and Clinical Attachment Level ) and the correlation between α-Amylase with flow rate of study groups that consist of ( patients had gingivitis and patients had chronic periodontitis with different severities(mild ,moderate ,severe) and control group . Ma
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