The manuscript (Tuhfat al-Ashab wa Nuzhat al-Albab) by the author Ahmed bin Ibrahim al-Hanafi al-Srouji (d. 0ٓٔ AH / ٖٓٔٔ
AD), one of the important manuscripts because it is an encyclopedia characterized by the diversity of its topics
Atorvastatin calcium (ATR) is an antihyperlipidemic agent used for lowering blood cholesterol levels. However, it is very slightly soluble in water with poor oral bioavailability, which interferes with its therapeutic action. It is classified as a class II drug according to Biopharmaceutical Classification System (low solubility and high permeability).