Primary amide derivatives as histone deacetylase inhibitors (HDACIs) are very rare. This paper describes the synthesis of primary amide derivatives (compounds 6 and 7) that have the requirements to be histone deacetylase inhibitors of the zinc-binding type. Both of them exhibited good cytotoxicity against the tested cancer cell lines with much lower cytotoxicity against normal cell line.

ABSTRACT

The research aims to identify the role of scientific planning of inventory by determining the quantity of economic demand and the number of times of purchase and associated annual total costs to achieve a sufficient and appropriate level of inventory . The research was based on the case study methodology. Materials of increasing demand in the Institute of Technical Management and knowledge of the degree of conformity of the procurement plan with the standard indicators adopted in a scientific method ,its include economic order quantity and number of purchasing times .
one of The main results  of the research was  the existence of a large difference between the quantity of the economic purchase of ea

Incremental Sheet Metal Forming (ISMF) is a modern sheet metal forming technology which offers the possibility of manufacturing 3D complex parts of thin sheet metals using the CNC milling machine. The surface quality is a very important aspect in any manufacturing process. Therefore, this study focuses on the resultant residual stresses by forming parameters, namely; (tool shape, step over, feed rate, and slope angle) using Taguchi method for the products formed by single point incremental forming process (SPIF). For evaluating the surface quality, practical experiments to produce pyramid like shape have been implemented on aluminum sheets (AA1050) for thickness (0.9) mm. Three types of tool shape used in this work, the spherical tool ga

Abstract

The current research aims to identify the typical effect of Flower and Coscroft on expressive performance and the development of lateral thinking among literary fifth-grade students. To achieve the research objective, the researcher chose a sample of (90) female students from the fifth literary grade, with two experimental groups and a control group. The research groups are of six subjects. The research found that the two experimental groups have more expressive performance than the control group. Students of the first experimental group outperformed the students of the second experimental group in expressive performance and lateral thinking tests. In light of the findings of the research, the researcher

Research Summary :

      Praise be to God, Lord of the Worlds, and prayers and peace be upon the Master of the Messengers, his family and all his companions, then after:

     This is a brief research that contained its two rudders the command and its Style in Surat Al-Ma’idah a fundamental rhetorical study, and the study clarified the meaning of imperative in both;  the Arabic  language and in the terminology of the fundamentalists and rhetoricians in a concise manner, and then indicated the imperative of the command , the true meaning, and the meanings interpretated as an  imperative form. I have mentioned some verses of Surat Al-Ma’idah, so what I have quot

The current research aims to know the measurement of the fifth- secondary stage female  students' affliction with the social phobia . The research is confined to General directorate of Education in Baghdad / Al-Karkh/2 / for the academic year 2015-2016 and fifth-secondary stage female students. It has been used descriptive method and  exposed theoretical sides and previous studies concerning with the  social phobia.The procedures of the research include the application of the  social phobia scale on random sample of  fifth- secondary stage female  students ( both  branches scientific and literary). The current study has concluded  that the  fifth- secondary stage female  students have&nbs

استهدف البحث الحالي قياس الذاكرة العاملة لدى التالميذ ذوي صعوبات تعلم القراءة، وتحقيقا ألهداف البحث اعد الباحثان اختبار الذاكرة العاملة للتالميذ ذوي صعوبات القراءة باستعمال مهام بصرية - سمعية وتنفيذية على وفق إنموذج بادلي)Baddely)، ثم استخرج الخصائص السيكومترية لكل منهما المتمثلة بالصدق والثبات. وتحدد البحث الحالي بالتالميذ ذوي صعوبات تعلم القراءة في المدارس االبتدائية التابعة للمدير ية العامة لتربية بابل ف

Has influenced technology contact on social values in the Arab community in general and
the Iraqi community in particular whether this positive change or a negative effect on the level
of the individual and society is reflected this influence through socialization and human
relations as well as the behavior of individuals and dealing with others, where the world was
to soon pass changes slow, and the amounts that can be measured and trends can be calculated
and the effect of points can be identified and controlled, but the technological changes and
openness cognitive features that seemed evident in the last decade of the twentieth century
brought about a change in all scales and distances traditional considerations.<

هدف البحث الحالي إلى عامل البخل المعرفي الذي يعد من العوامل التي تعطل الأفراد سعي الى الادراك المتمثل بالبيئة المادية والمعرفية والعالم المحيط بهم فهو يجعل الأفراد لا يرغبون في بذل المزيد من الجهد والوقت في التفكير والتحليل مما يؤدي الي معوقات في الإدراك، فالبخل المعرفي هو اعتماد الفرد الاختصارات العقلية والاستدلالات العقلية السريعة للحفاظ على الموارد العقلية عند التعامل مع المهام التي تتطلب في المقام الا