The present work describes guggul as a novel carrier for some anti-inflammatory drugs. Guggulusomes containing different concentration of guggul with aceclofenac were prepared by sonication method and characterized for vesicle shape, size, size-distribution, pH, viscosity, spread ability, homogeneity, and accelerated stability in-vitro drug permeation through mouse skin. The vesicles exhibited an entrapment efficiency of 93.2 ± 12%, vesicle size of 0.769 ± 3μm and a zeta potential of - 6.21mV. In vitro drug release was analyzed using Franz’s diffusion cells. The cumulative release of the guggulusomes gel (G2) was 75.8% in 18 hrs, which is greater than that all the gel formulation. The stability profile of prepare

The method of solving volterra integral equation by using numerical solution is a simple operation but to require many memory space to compute and save the operation. The importance of this equation appeares new direction to solve the equation by using new methods to avoid obstacles. One of these methods employ neural network for obtaining the solution.

This paper presents a proposed method by using cascade-forward neural network to simulate volterra integral equations solutions. This method depends on training cascade-forward neural network by inputs which represent the mean of volterra integral equations solutions, the target of cascade-forward neural network is to get the desired output of this network. Cascade-forward neural

This paper derives the EDITRK4 technique, which is an exponentially fitted diagonally implicit RK method for solving ODEs . This approach is intended to integrate exactly initial value problems (IVPs), their solutions consist of linear combinations of the group functions  and  for exponentially fitting  problems, with  being the problem’s major frequency utilized to improve the precision of the method. The modified  method EDITRK4 is a new three-stage fourth-order exponentially-fitted diagonally implicit approach for solving IVPs with functions that are exponential as solutions. Different forms of -order ODEs must be derived using the modified system, and when the same issue is reduced to a  framework of equations that can be sol

Voice denoising is the process of removing undesirable voices from the voice signal. Within the environmental noise and after the application of speech recognition system, the discriminative model finds it difficult to recognize the waveform of the voice signal. This is due to the fact that the environmental noise needs to use a suitable filter that does not affect the shaped waveform of the input microphone. This paper plans to build up a procedure for a discriminative model, using infinite impulse response filter (Butterworth filter) and local polynomial approximation (Savitzky-Golay) smoothing filter that is a polynomial regression on the signal values. Signal to noise ratio (SNR) was calculated after filtering to compare the results

thirty adult NewZealand rabbits used in this study, they were divided in to two groups (control and treaded with Helium — Neon laser). A square skin flap done on the medial aspect of the auricle of both sides, a square piece of cartilage incised, pealed out from each auricle and fixed in the site of the other, then the flaps sutured .The site of the operation in the rabbits of the treated group were irradiated using a Helium —Neon laser with (5mw) power for (10 days) began after the operation directly, (3 rabbits) from each group used for collection of specimens for histopathological examination at the weeks (1,2,3,4, & 6) weeks post the operation .The results revealed Early invasion of the matrix with elastic fibers which continue to t

Visible light communication (VLC) is an upcoming wireless technology for next-generation communication for high-speed data transmission. It has the potential for capacity enhancement due to its characteristic large bandwidth. Concerning signal processing and suitable transceiver design for the VLC application, an amplification-based optical transceiver is proposed in this article. The transmitter consists of a driver and laser diode as the light source, while the receiver contains a photodiode and signal amplifying circuit. The design model is proposed for its simplicity in replacing the trans-impedance and transconductance circuits of the conventional modules by a simple amplification circuit and interface converter. Th

The Indoor Environmental Quality (IEQ) describes an indoor space condition that the wellbeing and comfortability are provided for the users. Many researchers have highlighted the importance of adopting IEQ criteria, although they are not yet well defined in the Kurdistan region. However, environmental quality is not necessary for the contemporary buildings of the Kurdistan Region, and there is no measurement tool in the Region. This research aims to develop an IEQ assessment tool for the Kurdistan region using Mixed method methodology, both qualitative and quantitative. Therefore, a Delphi Technique was used as a method initially developed as systematic, interactive forecasting on a panel of experts. Thirty-five Delphi C

Storage tanks condition and integrity is maintained by joint application of coating and cathodic protection. Iraq southern region rich in oil and petroleum product refineries need and use plenty of aboveground storage tanks. Iraq went through conflicts over the past thirty five years resulting in holding the oil industry infrastructure behind regarding maintenance and modernization. The primary concern in this work is the design and implementation of cathodic protection systems for the aboveground storage tanks farm in the oil industry.

Storage tank external base area and tank internal surface area are to be protected against corrosion using impressed current and sacrificial anode cathodic protection systems. Int

Darifenacin hydrobromide is a selective ?₃ receptor antimuscarinic drug and it is used in the management of urinary frequency, urgency, and incontinence in detrusor instability. It slightly soluble in water, undergoes extensive hepatic first-pass metabolism and has short elimination half-life (3–4 hours). Therefore, It has low bioavailability (15.4 % - 18.6 %). Darifenacin hydrobromide loaded NLCs were formulated by emulsification sonication using different ratios of solid lipid to liquid lipid, different types of surfactants, and different concentration of surfactants. Formula sixteen was considered as an optimized formula based on its particle size, PDI, zeta potential and entrapment efficiency. Formula sixteen subjected t