Objectives: To study the spectrum and classification of ATP7B variants in Iraqi children with Wilson disease by direct gene sequencing with clinical correlation. Methods: Fifty-five unrelated children with a clinical diagnosis of Wilson disease (WD) were recruited. Deoxyribonucleic acid was extracted from peripheral blood samples, and variants in the ATP7B gene were identified using next-generation sequencing. Results: Seventy-six deleterious variants were detected in 97 out of 110 alleles of the ATP7B gene. Thirty (54.5%) patients had 2 disease-causing variants (15 homozygous and 15 compound heterozygous). Twelve (21.8%) patients had one disease-causing variant and one variant of uncertain significance (VUS) with potential pathogenicity. T

          Seeks this research is to clarify the role played by TQM represented Bmngaradtha (commitment and support of senior management of the philosophy of TQM, strategic planning for the overall quality, focus on the customer, continuous improvement, post workers, training and rehabilitation of workers) to achieve sustainable competitive advantage represented by dimensions (estimated intrinsic , creative culture, information technology, strategic flexibility), research has relied on the views of a sample of managers working in the Iraqi public insurance company. So identified research problem in answering the following questions: "What is the size of visualization owned by managers in the co

The poet dependent formation of a caupillary to stimuli ,sensory based on the areas of cognition in cluding raises every sense in the mind of therecipient , taking advantage of the senses which help him to perception and imagination and photography .i wanted in my Research that showed silent in the poetry of muslim Ibn al walid by the method of use the senses and then method of imaging divided the research to the axes according to topics hair began to praise ,I have found through mating poetic image with silent about the poet in the purpose of praise that he wanted . the caliphate of yazidI bnmazidknignt courageous , and thisis found in the clear signals in the poems silent poet what he wanting saying . The purpose that I choose to look out

The research revolves around the methodology of the historian Ibn Wasil
(d.697 AH) in dealing with the Mongolian invasion through his book
“Mafrej al-Karroub fi Akhbar Bani Ayyub

Abstract

Due to increased interest on organizations and the human element, organizational and environmental aspects of the organization Has been analyzed, and behavioral aspects of the members and what is the impact of each on the other, To give the recipe interaction between the organization and its environment, in order to bring about change in behavior appeared the concept of organizational health as a concept in a modern organizations, Either the organization to be stimulating good, healthy, and then called healthy organization Or that the situation be frustrating it is not good and unhealthy, so the cause of tension and anxiety, unhealthy organization is here The research aim to determine the existence of organizatio

Chapter One – introduction

Nations managed today to achieve progress in the field of modern technology. Science has changed many beliefs and trendiness that people have held for long time, skills and scientific thinking developed, and made scientific observation  and experiment replace narration and taking from others. That is attributed to examining  the educational systems searching for the locations of defect, and shortage.

In the light of educational modernizations, many models of teaching incliuding a model for social tracing attributed to Herbart Thelen, which is a model to develop skills of social participation in the democratic process (Al-Khawalda,1993,335).