Flexible molecular docking is a computational method of structure-based drug design to evaluate binding interactions between receptor and ligand and identify the ligand conformation within the receptor pocket. Currently, various molecular docking programs are extensively applied; therefore, realizing accuracy and performance of the various docking programs could have a significant value. In this comparative study, the performance and accuracy of three widely used non-commercial docking software (AutoDock Vina, 1-Click Docking, and UCSF DOCK) was evaluated through investigations of the predicted binding affinity and binding conformation of the same set of small molecules (HIV-1 protease inhibitors) and a protein target HIV-1 protease enzy

Neural cryptography deals with the problem of “key exchange” between two neural networks by using the mutual learning concept. The two networks exchange their outputs (in bits) and the key between two communicating parties ar eventually represented in the final learned weights, when the two networks are said to be synchronized. Security of neural synchronization is put at risk if an attacker is capable of synchronizing with any of the two parties during the training process.

Home Computer and Information Science 2009 Chapter The Stochastic Network Calculus Methodology Deah J. Kadhim, Saba Q. Jobbar, Wei Liu & Wenqing Cheng Chapter 568 Accesses 1 Citations Part of the Studies in Computational Intelligence book series (SCI,volume 208) Abstract The stochastic network calculus is an evolving new methodology for backlog and delay analysis of networks that can account for statistical multiplexing gain. This paper advances the stochastic network calculus by deriving a network service curve, which expresses the service given to a flow by the network as a whole in terms of a probabilistic bound. The presented network service curve permits the calculation of statistical end-to-end delay and backlog bounds for broad

In this paper, we introduce a method to identify the text printed in Arabic, since the recognition of the printed text is very important in the applications of information technology, the Arabic language is among a group of languages with related characters such as the language of Urdu , Kurdish language , Persian language also the old Turkish language " Ottoman ", it is difficult to identify the related letter because it is in several cases, such as the beginning of the word has a shape and center of the word has a shape and the last word also has a form, either texts in languages where the characters are not connected, then the image of the letter one in any location in the word has been Adoption of programs ready for him A long time.&

Zerumbone (ZER), a natural compound has been extracted from Zingiber zerumbet with known pharmacological activities. The aim was to determine the anti-human Burkitt’s lymphoma (Raji) cell effect of ZER. The 3-(4,5-dimethylthiazol-2-yl)-2,5,-diphenyltetrazolium bromide (MTT) assay was used to determine cytotoxic effect while the Annexin-V-fluorescein isothiocyanate/propidium iodide-PI flow cytometric assays was used to determine apoptotic effect of ZER on the human Burkitt’s lymphoma (Raji) cell (ATCC CCL-86) cell line. The expressions of Bax, Bcl-2, and c-Myc genes were determined via real-time PCR. ZER suppressed the proliferation of Raji cells with a 48 h IC50 value of 5.1 μg/mL. Treated Raji cells also underwen

  Manufacturing systems of the future foresee the use of intelligent vehicles, optimizing and navigating. The navigational problem is an important and challenging problem in the field of robotics. The robots often find themselves in a situation where they must find a trajectory to another position in their environment, subject to constraints posed by obstacles and the capabilities of the robot itself. On-line navigation is a set of algorithms that plans and executes a trajectory at the same time.         The system adopted in this research searches for a robot collision-free trajectory in a dynamic environment in which obstacles can move while the robot was moving toward the target. So, the ro

teen sites Baghdad are made. The sites are divided into two groups, one in Karkh and the other in Rusafa. Assessing the underground conditions can be occurred by drilling vertical holes called exploratory boring into the ground, obtaining soil (disturbed and undisturbed) samples, and testing these samples in a laboratory (civil engineering laboratory /University of Baghdad). From disturbed, the tests involved the grain size analysis and then classified the soil, Atterberg limit, chemical test (organic content, sulphate content, gypsum content and chloride content). From undisturbed samples, the test involved the consolidation test (from this test, the following parameters can be obtained: initial void ratio eo, compression index cc, swel